About 793 results

ALLMedicine™ Lipid Disorders Center

Research & Reviews  254 results

PHIP gene variants with protein modeling, interactions, and clinical phenotypes.
American Journal of Medical Genetics. Part A; Dietrich J, Lovell S et. al.

Nov 14th, 2021 - Variants in the pleckstrin homology domain-interacting protein (PHIP) gene are implicated in the clinical phenotype of Chung-Jansen syndrome, which includes dysmorphic features, cognitive dysfunction, aberrant behavior, and childhood onset obesity...

COVID-19 and lipids. The role of lipid disorders and statin use in the prognosis of pat...
Lipids in Health and Disease; Surma S, Banach M et. al.

Oct 26th, 2021 - The global coronavirus disease 2019 (COVID-19) pandemic caused by the SARS-CoV-2 coronavirus started in March 2020. The conclusions from numerous studies indicate that people with comorbidities, such as arterial hypertension, diabetes, obesity, un...

A modern approach to dyslipidemia.
Endocrine Reviews; Berberich AJ, Hegele RA

Oct 23rd, 2021 - Lipid disorders involving derangements in serum cholesterol, triglycerides or both are commonly encountered in clinical practice and often have implications for cardiovascular risk and overall health. Recent advances in knowledge, recommendations ...

Is treating severe He FH so easy? A combined treatment between lipoprotein apheresis an...
Transfusion and Apheresis Science : Official Journal of T... Dal Pino B, Sbrana F et. al.

Oct 23rd, 2021 - Despite advance in pharmacotherapy of lipid disorders, many heterozygous Familial Hypercholesterolemia patients do not achieve a desirable lipid target to significantly reduce the risk of atherosclerotic cardiovascular disease. The aim of the pres...

Treatment of Mixed Dyslipidemia With Alirocumab in a Kidney Transplant Recipient: A Cas...
Transplantation Proceedings; Papasotiriou M, Ntrinias T et. al.

Oct 5th, 2021 - Dyslipidemia is common in kidney transplant recipients owing to the disturbance of lipid metabolism caused by chronic kidney disease and the effect of immunosuppression on lipid metabolism. Patients receiving treatment with mammalian target of rap...

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Guidelines  2 results

Screening for Lipid Disorders in Children and Adolescents: Recommendation Statement.
American Family Physician;

Jan 12th, 2017 - Screening for Lipid Disorders in Children and Adolescents: Recommendation Statement.|2017||therapeutic use,diagnosis,therapy,diagnosis,drug therapy,

Statin Use for the Primary Prevention of Cardiovascular Disease in Adults: US Preventiv...
JAMA , Bibbins-Domingo K et. al.

Nov 14th, 2016 - Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in the United States, accounting for 1 of every 3 deaths among adults. To update the 2008 US Preventive Services Task Force (USPSTF) recommendation on screening for lipid...

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Drugs  1 results see all →

Clinicaltrials.gov  4 results

Genes Involved in Lipid Disorders

Sep 17th, 2021 - The primary purpose of this discovery protocol is to identify new lipid genes from subjects with rare genetic lipids disorders. We will take advantage of the new technology of whole exome sequencing to find the cause of dyslipidemia that we haven ...

Calorimetry, Insulin Resistance and Energy Metabolism Study to Understand the Risk of Obesity in Kidney Transplanted Patients

Jul 8th, 2014 - Weight gain is a common complication after transplantation. It has adverse effects such as hypertension, dyslipidemia, and insulin resistance. Weight gain is implicated in the increased cardiovascular risk and the long-term loss of graft function....

The Effects of a Mediterranean Diet in Pediatric Hyperlipidemia

Jan 27th, 2014 - Children with high cholesterol levels are especially vulnerable and are at high risk for early onset coronary heart disease (CHD). Endothelial dysfunction, the earliest phase of CHD, is present in children with elevated cholesterol levels as early...

Safety and Efficacy in LPL-Deficient Subjects of AMT-011, an Adeno-Associated Viral Vector Expressing Human Lipoprotein Lipase [S447X]

Sep 30th, 2011 - The CT-AMT-011-01 study is an open-label, dose-escalating study evaluating the safety and efficacy of a single intramuscular administration of AMT-011 (at multiple sites). The study will be performed in the Community Genomic medicineCenter (CGMC) ...

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News  56 results

Cognitive Function in Diabetes: How to Protect Our Patients

Feb 10th, 2021 - People with diabetes pose a particular challenge when trying to assess cognitive function longitudinally. Population data suggest that the risk of developing dementia, both vascular and neurodegenerative, among people with diabetes followed for 20...

AACE Issues 'Cookbook' Algorithm to Manage Dyslipidemia

Oct 29th, 2020 - Dr Yehuda Handelsman A new algorithm on lipid management and prevention of cardiovascular disease from the American Association of Clinical Endocrinologists* (AACE) and the American College of Endocrinology (ACE) is "a nice cookbook" that many cli...

'Biosimilar' Insulin Glargine, Semglee, Approved for Diabetes in US

Jun 13th, 2020 - Semglee, a long-acting human insulin analogue, has been approved for glycemic control in adults and children with type 1 diabetes and adults with type 2 diabetes, the Food and Drug Administration announced June 11. "Long-acting insulin products li...

A Cardiologist's Diet Built for Improving Cholesterol

Oct 29th, 2019 - As a cardiologist, patients often ask me for ways to lower their cholesterol without taking statins. They wonder how effective and viable alternatives can be and what strategies they can use to lower their cholesterol in other ways. I often tell m...

200 cardiovascular drugs now in development
Richard Franki, MDedge News

Mar 2nd, 2018 - Heart failure, with 42 medicines currently in development, is the leading area for new treatments of cardiovascular disease, according to Pharmaceutical Research and Manufacturers of America. One of those 42 treatments is “a nonviral gene therapy.

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