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ALLMedicine™ Peptic Ulcer Disease Center

Research & Reviews  1,479 results

Evidence-based clinical practice guidelines for peptic ulcer disease 2020.
https://doi.org/10.1007/s00535-021-01769-0 10.1007/s00535-014-1016-1 10.1111/den.12183 10.1111/den.13184 10.1136/gutjnl-2015-311304 10.1111/apt.13876 10.1136/gutjnl-2017-314010 10.1136/gutjnl-2017-314852 10.7326/0003-4819-152-1-201001050-00179 10.1186/s13017-019-0223-8 10.1055/s-0034-1365235 10.1046/j.1365-2036.2000.00822.x 10.1111/j.1365-2036.2005.02546.x 10.5152/tjg.2018.17143 10.1111/bcp.12866 10.1155/2009/191706 10.1056/NEJMoa1007964 10.3892/etm.2016.3693 10.1093/eurheartj/ehx419 10.1053/j.gastro.2016.08.054 10.1111/hel.12597 10.1111/j.1523-5378.2007.00508.x 10.3389/fphar.2018.01560 10.1136/gutjnl-2016-312288 10.3390/jcm9020543 10.3748/wjg.v21.i2.661 10.1038/ajg.2017.195 10.1038/ajg.2015.439 10.1159/000454762 10.3748/wjg.v23.i4.668 10.2169/internalmedicine.56.7833 10.1007/s00535-012-0731-8 10.1111/jgh.12442 10.1111/hel.12286 10.1007/BF02088227 10.1186/1471-230X-2-17 10.1016/S0149-2918(97)80098-7 10.1007/s40262-015-0326-7 10.1093/rheumatology/32.6.474 10.1001/archinte.160.10.1455 10.1056/NEJM199803123381105 10.1016/S0140-6736(02)07272-0 10.1111/j.1365-2036.2005.02444.x 10.1111/j.1523-5378.2012.00942.x 10.1056/NEJM199605303342204 10.1016/S2468-1253(18)30037-2 10.1016/S1590-8658(00)80402-8 10.1007/s00535-012-0541-z 10.1111/j.1365-2036.2012.05133.x 10.1016/S0140-6736(07)60749-1 10.1053/j.gastro.2014.06.007 10.1186/ar2207 10.1016/S0140-6736(99)02332-6 10.1016/S0016-5085(99)70334-3 10.1093/rheumatology/keg359 10.1111/apt.12174 10.1046/j.1365-2036.2003.01650.x 10.3748/wjg.14.4535 10.1111/apt.13642 10.1038/ajg.2012.87 10.3748/wjg.v21.i17.5382 10.1371/journal.pone.0131558 10.1053/j.gastro.2016.09.006 10.1053/j.gastro.2009.09.063 10.1038/ajg.2011.385 10.1016/j.cgh.2011.05.020 10.1253/circj.CJ-12-0511 10.1016/j.ahj.2011.08.007 10.1056/NEJM200103293441304 10.1056/NEJMoa012877 10.1007/s00535-011-0397-7 10.1007/s00535-012-0588-x 10.1111/apt.12907 10.1136/gutjnl-2013-304722 10.1016/S0140-6736(09)61246-0 10.1111/jgh.12768 10.1136/hrt.2010.217547 10.1053/j.gastro.2004.05.001 10.1016/S0140-6736(07)61909-6 10.1111/j.1365-2036.2006.02912.x 10.1016/j.cgh.2007.06.009 10.1016/S0140-6736(17)30981-9 10.1056/NEJMoa1611593 10.1001/jama.296.13.jrv60011 10.1016/j.clinthera.2004.10.002 10.1111/j.1365-2036.2010.04378.x 10.1136/gut.34.6.762 10.1111/den.12635 10.1053/j.gastro.2009.05.006 10.1136/gutjnl-2019-318715 10.1111/j.1572-0241.1998.00279.x 10.1007/s00268-005-7797-x 10.1097/00000658-200002000-00001 10.1046/j.0007-1323.2001.01831.x 10.1111/j.1523-5378.2011.00928.x 10.1016/j.ijsu.2008.12.001 10.1007/BF01308523 10.1016/S0027-9684(15)31248-7
Journal of Gastroenterology; Kamada T, Satoh K et. al.

Feb 23rd, 2021 - The Japanese Society of Gastroenterology (JSGE) revised the third edition of evidence-based clinical practice guidelines for peptic ulcer disease in 2020 and created an English version. The revised guidelines consist of nine items: epidemiology, h...

Aspirin Is Safe for Venous Thromboembolism Prophylaxis for Patients With a History of G...
https://doi.org/10.1016/j.arth.2021.01.069
The Journal of Arthroplasty; Grosso MJ, Kozaily E et. al.

Feb 21st, 2021 - The safety of acetylsalicylic acid (ASA, aspirin) in patients with prior history of gastroesophageal reflux or peptic ulcer disease remains unclear. The purpose of this study was to determine the safety of ASA for venous thromboembolism (VTE) prop...

GWAS of peptic ulcer disease implicates Helicobacter pylori infection, other gastrointe...
https://doi.org/10.1038/s41467-021-21280-7 10.1053/j.gastro.2018.08.063 10.1136/gut.2006.117598 10.1053/gast.2002.32392 10.1111/j.1572-0241.2006.00630.x 10.1016/S0140-6736(16)32404-7 10.1111/apt.12465 10.1111/nmo.13017 10.1136/gutjnl-2012-304269 10.1056/NEJMra1207068 10.1038/nrgastro.2015.34 10.1016/S0140-6736(17)32448-0 10.1001/archinte.160.1.105 10.1136/gut.52.8.1085 10.1016/j.gtc.2010.12.011 10.1093/hmg/ddu174 10.1002/cti2.1001 10.1038/ng.1109 10.1038/s41467-019-11968-2 10.1136/gutjnl-2014-307997 10.1038/ajg.2014.56 10.1053/j.gastro.2018.03.064 10.1126/scitranslmed.aap8914 10.1038/nrn3071 10.1038/nrgastro.2012.32 10.1136/gut.47.6.861 10.1097/MD.0000000000002333 10.3748/wjg.v21.i14.4302 10.1007/s00406-014-0502-z 10.1136/gut.2003.019844 10.1016/j.ajhg.2010.11.011 10.1038/ng.2213 10.1534/genetics.115.178616 10.1038/s41467-017-02317-2 10.1038/s41467-017-01261-5 10.1093/nar/gkw1133 10.1038/ng.3211 10.1093/bioinformatics/btw613 10.1038/s41588-018-0269-7 10.1038/s41588-018-0059-2 10.1038/mp.2015.197 10.1038/mp.2017.77 10.1038/s41588-019-0397-8 10.1038/s41588-019-0344-8 10.1038/s41588-018-0090-3 10.1038/s41398-018-0150-6 10.1016/S1474-4422(19)30320-5 10.1038/ng.3552 10.1038/ng.3888 10.1038/ng.3749 10.1038/nature14177 10.1038/nature14132 10.1038/ng.3396 10.1038/ng.2383 10.1038/nature17671 10.1038/s41588-018-0081-4 10.1126/science.1262110 10.1038/ng.3173 10.1038/s41588-018-0147-3 10.1038/s41588-018-0307-5 10.1038/ng.3538 10.1038/s41598-018-35871-w 10.1038/nature14248 10.1371/journal.pcbi.1004219 10.1038/s41588-020-0594-5 10.1038/s41588-018-0255-0 10.18632/oncotarget.23278 10.1093/aje/kwq299 10.1371/journal.pgen.1000072 10.1038/srep25575 10.12688/wellcomeopenres.14636.2 10.1053/j.gastro.2007.07.003 10.3748/wjg.v21.i31.9430 10.4172/2161-069X.1000123 10.1158/0008-5472.CAN-15-2272 10.1016/j.jns.2016.03.005 10.1517/14728214.2015.1049996 10.1038/ng.2796 10.1073/pnas.1911429116 10.1172/JCI76307 10.1136/gut.51.6.885 10.1016/j.amjsurg.2013.02.012 10.1038/s41598-018-29629-7 10.1038/s41467-019-09572-5 10.1046/j.1442-2050.2002.00261.x 10.1159/000485190 10.1056/NEJMoa1915784 10.1111/j.1365-2036.2008.03596.x 10.1017/S0033291717000745 10.1093/ije/dyx206 10.1038/s41586-018-0579-z 10.1093/hmg/ddy271 10.1186/s13742-015-0047-8 10.1136/gut.2010.224154 10.1038/nrd.2016.230 10.1093/bioinformatics/btq559 10.3389/fgene.2012.00118 10.1111/j.1469-1809.1965.tb00500.x 10.1111/j.1469-1809.1972.tb00767.x 10.1038/s41588-018-0144-6 10.1534/genetics.117.300360 10.1093/bioinformatics/btq419 10.1186/s12864-015-2347-x 10.1038/ng.3406 10.1038/ng.3404 10.1101/gr.229102 10.1038/nature10530 10.1038/nature11247 10.1038/s41467-018-04558-1 10.1073/pnas.0506580102 10.1016/j.cels.2015.12.004 10.1002/gepi.21758 10.1093/ije/dyv080 10.1002/gepi.21965 10.1038/s41588-018-0099-7 10.1186/1471-2105-12-77
Nature Communications; Wu Y, Murray GK et. al.

Feb 20th, 2021 - Genetic factors are recognized to contribute to peptic ulcer disease (PUD) and other gastrointestinal diseases, such as gastro-oesophageal reflux disease (GORD), irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD). Here, genome-wid...

Systematic Review and Meta-Analysis of Prophylactic Transarterial Embolization for High...
https://doi.org/10.1016/j.jvir.2020.12.005
Journal of Vascular and Interventional Radiology : JVIR; Chang JHE, Lye TJY et. al.

Feb 2nd, 2021 - The present systematic review determined the role of transarterial embolization (TAE) as a prophylactic treatment in bleeding peptic ulcers after initial successful endoscopic hemostasis. PubMed and Ovid Medline databases were searched from incept...

Cryo-EM structure of Helicobacter pylori urease with an inhibitor in the active site at...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801526
Nature Communications; Cunha ES, Chen X et. al.

Jan 12th, 2021 - Infection of the human stomach by Helicobacter pylori remains a worldwide problem and greatly contributes to peptic ulcer disease and gastric cancer. Without active intervention approximately 50% of the world population will continue to be infecte...

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Guidelines  11 results

ACG Clinical Guideline: Treatment of Helicobacter pylori Infection.
https://doi.org/10.1038/ajg.2016.563
The American Journal of Gastroenterology; Chey WD, Leontiadis GI et. al.

Jan 10th, 2017 - Helicobacter pylori (H. pylori) infection is a common worldwide infection that is an important cause of peptic ulcer disease and gastric cancer. H. pylori may also have a role in uninvestigated and functional dyspepsia, ulcer risk in patients taki...

Treatment of Helicobacter pylori Infection: ACG Guidelines
http://gi.org/guideline/treatment-of-helicobacter-pylori-infection/
Chey WC

Jan 9th, 2017 - Helicobacter pylori (H. pylori) infection is a common worldwide infection that is an important cause of peptic ulcer disease and gastric cancer.

Evidence-based clinical practice guidelines for peptic ulcer disease 2015.
https://doi.org/10.1007/s00535-016-1166-4
Journal of Gastroenterology; Satoh K, Yoshino J et. al.

Feb 17th, 2016 - The Japanese Society of Gastroenterology (JSGE) revised the evidence-based clinical practice guidelines for peptic ulcer disease in 2014 and has created an English version. The revised guidelines consist of seven items: bleeding gastric and duoden...

Quality indicators for EGD
https://www.asge.org/docs/default-source/education/practice_guidelines/doc-b68366e5-03fd-429d-8150-77193bec8873.pdf?sfvrsn=6
Walter G. Park

Nov 30th, 2014 - EGD is used widely for the diagnosis and treatment of esophageal, gastric, and small-bowel disorders. When properly performed, it is generally safe and well-tolerated for the examination of the upper GI tract.

Management of Patients with Ulcer Bleeding
http://gi.org/guideline/management-of-patients-with-ulcer-bleeding/
Laine, L.,et al

Feb 6th, 2012 - This guideline presents recommendations for the step-wise management of patients with overt upper gastrointestinal bleeding. Hemodynamic status is first assessed, and resuscitation initiated as needed.

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Drugs  4 results see all →

Clinicaltrials.gov  1,567 results

Evidence-based clinical practice guidelines for peptic ulcer disease 2020.
https://doi.org/10.1007/s00535-021-01769-0 10.1007/s00535-014-1016-1 10.1111/den.12183 10.1111/den.13184 10.1136/gutjnl-2015-311304 10.1111/apt.13876 10.1136/gutjnl-2017-314010 10.1136/gutjnl-2017-314852 10.7326/0003-4819-152-1-201001050-00179 10.1186/s13017-019-0223-8 10.1055/s-0034-1365235 10.1046/j.1365-2036.2000.00822.x 10.1111/j.1365-2036.2005.02546.x 10.5152/tjg.2018.17143 10.1111/bcp.12866 10.1155/2009/191706 10.1056/NEJMoa1007964 10.3892/etm.2016.3693 10.1093/eurheartj/ehx419 10.1053/j.gastro.2016.08.054 10.1111/hel.12597 10.1111/j.1523-5378.2007.00508.x 10.3389/fphar.2018.01560 10.1136/gutjnl-2016-312288 10.3390/jcm9020543 10.3748/wjg.v21.i2.661 10.1038/ajg.2017.195 10.1038/ajg.2015.439 10.1159/000454762 10.3748/wjg.v23.i4.668 10.2169/internalmedicine.56.7833 10.1007/s00535-012-0731-8 10.1111/jgh.12442 10.1111/hel.12286 10.1007/BF02088227 10.1186/1471-230X-2-17 10.1016/S0149-2918(97)80098-7 10.1007/s40262-015-0326-7 10.1093/rheumatology/32.6.474 10.1001/archinte.160.10.1455 10.1056/NEJM199803123381105 10.1016/S0140-6736(02)07272-0 10.1111/j.1365-2036.2005.02444.x 10.1111/j.1523-5378.2012.00942.x 10.1056/NEJM199605303342204 10.1016/S2468-1253(18)30037-2 10.1016/S1590-8658(00)80402-8 10.1007/s00535-012-0541-z 10.1111/j.1365-2036.2012.05133.x 10.1016/S0140-6736(07)60749-1 10.1053/j.gastro.2014.06.007 10.1186/ar2207 10.1016/S0140-6736(99)02332-6 10.1016/S0016-5085(99)70334-3 10.1093/rheumatology/keg359 10.1111/apt.12174 10.1046/j.1365-2036.2003.01650.x 10.3748/wjg.14.4535 10.1111/apt.13642 10.1038/ajg.2012.87 10.3748/wjg.v21.i17.5382 10.1371/journal.pone.0131558 10.1053/j.gastro.2016.09.006 10.1053/j.gastro.2009.09.063 10.1038/ajg.2011.385 10.1016/j.cgh.2011.05.020 10.1253/circj.CJ-12-0511 10.1016/j.ahj.2011.08.007 10.1056/NEJM200103293441304 10.1056/NEJMoa012877 10.1007/s00535-011-0397-7 10.1007/s00535-012-0588-x 10.1111/apt.12907 10.1136/gutjnl-2013-304722 10.1016/S0140-6736(09)61246-0 10.1111/jgh.12768 10.1136/hrt.2010.217547 10.1053/j.gastro.2004.05.001 10.1016/S0140-6736(07)61909-6 10.1111/j.1365-2036.2006.02912.x 10.1016/j.cgh.2007.06.009 10.1016/S0140-6736(17)30981-9 10.1056/NEJMoa1611593 10.1001/jama.296.13.jrv60011 10.1016/j.clinthera.2004.10.002 10.1111/j.1365-2036.2010.04378.x 10.1136/gut.34.6.762 10.1111/den.12635 10.1053/j.gastro.2009.05.006 10.1136/gutjnl-2019-318715 10.1111/j.1572-0241.1998.00279.x 10.1007/s00268-005-7797-x 10.1097/00000658-200002000-00001 10.1046/j.0007-1323.2001.01831.x 10.1111/j.1523-5378.2011.00928.x 10.1016/j.ijsu.2008.12.001 10.1007/BF01308523 10.1016/S0027-9684(15)31248-7
Journal of Gastroenterology; Kamada T, Satoh K et. al.

Feb 23rd, 2021 - The Japanese Society of Gastroenterology (JSGE) revised the third edition of evidence-based clinical practice guidelines for peptic ulcer disease in 2020 and created an English version. The revised guidelines consist of nine items: epidemiology, h...

Aspirin Is Safe for Venous Thromboembolism Prophylaxis for Patients With a History of G...
https://doi.org/10.1016/j.arth.2021.01.069
The Journal of Arthroplasty; Grosso MJ, Kozaily E et. al.

Feb 21st, 2021 - The safety of acetylsalicylic acid (ASA, aspirin) in patients with prior history of gastroesophageal reflux or peptic ulcer disease remains unclear. The purpose of this study was to determine the safety of ASA for venous thromboembolism (VTE) prop...

GWAS of peptic ulcer disease implicates Helicobacter pylori infection, other gastrointe...
https://doi.org/10.1038/s41467-021-21280-7 10.1053/j.gastro.2018.08.063 10.1136/gut.2006.117598 10.1053/gast.2002.32392 10.1111/j.1572-0241.2006.00630.x 10.1016/S0140-6736(16)32404-7 10.1111/apt.12465 10.1111/nmo.13017 10.1136/gutjnl-2012-304269 10.1056/NEJMra1207068 10.1038/nrgastro.2015.34 10.1016/S0140-6736(17)32448-0 10.1001/archinte.160.1.105 10.1136/gut.52.8.1085 10.1016/j.gtc.2010.12.011 10.1093/hmg/ddu174 10.1002/cti2.1001 10.1038/ng.1109 10.1038/s41467-019-11968-2 10.1136/gutjnl-2014-307997 10.1038/ajg.2014.56 10.1053/j.gastro.2018.03.064 10.1126/scitranslmed.aap8914 10.1038/nrn3071 10.1038/nrgastro.2012.32 10.1136/gut.47.6.861 10.1097/MD.0000000000002333 10.3748/wjg.v21.i14.4302 10.1007/s00406-014-0502-z 10.1136/gut.2003.019844 10.1016/j.ajhg.2010.11.011 10.1038/ng.2213 10.1534/genetics.115.178616 10.1038/s41467-017-02317-2 10.1038/s41467-017-01261-5 10.1093/nar/gkw1133 10.1038/ng.3211 10.1093/bioinformatics/btw613 10.1038/s41588-018-0269-7 10.1038/s41588-018-0059-2 10.1038/mp.2015.197 10.1038/mp.2017.77 10.1038/s41588-019-0397-8 10.1038/s41588-019-0344-8 10.1038/s41588-018-0090-3 10.1038/s41398-018-0150-6 10.1016/S1474-4422(19)30320-5 10.1038/ng.3552 10.1038/ng.3888 10.1038/ng.3749 10.1038/nature14177 10.1038/nature14132 10.1038/ng.3396 10.1038/ng.2383 10.1038/nature17671 10.1038/s41588-018-0081-4 10.1126/science.1262110 10.1038/ng.3173 10.1038/s41588-018-0147-3 10.1038/s41588-018-0307-5 10.1038/ng.3538 10.1038/s41598-018-35871-w 10.1038/nature14248 10.1371/journal.pcbi.1004219 10.1038/s41588-020-0594-5 10.1038/s41588-018-0255-0 10.18632/oncotarget.23278 10.1093/aje/kwq299 10.1371/journal.pgen.1000072 10.1038/srep25575 10.12688/wellcomeopenres.14636.2 10.1053/j.gastro.2007.07.003 10.3748/wjg.v21.i31.9430 10.4172/2161-069X.1000123 10.1158/0008-5472.CAN-15-2272 10.1016/j.jns.2016.03.005 10.1517/14728214.2015.1049996 10.1038/ng.2796 10.1073/pnas.1911429116 10.1172/JCI76307 10.1136/gut.51.6.885 10.1016/j.amjsurg.2013.02.012 10.1038/s41598-018-29629-7 10.1038/s41467-019-09572-5 10.1046/j.1442-2050.2002.00261.x 10.1159/000485190 10.1056/NEJMoa1915784 10.1111/j.1365-2036.2008.03596.x 10.1017/S0033291717000745 10.1093/ije/dyx206 10.1038/s41586-018-0579-z 10.1093/hmg/ddy271 10.1186/s13742-015-0047-8 10.1136/gut.2010.224154 10.1038/nrd.2016.230 10.1093/bioinformatics/btq559 10.3389/fgene.2012.00118 10.1111/j.1469-1809.1965.tb00500.x 10.1111/j.1469-1809.1972.tb00767.x 10.1038/s41588-018-0144-6 10.1534/genetics.117.300360 10.1093/bioinformatics/btq419 10.1186/s12864-015-2347-x 10.1038/ng.3406 10.1038/ng.3404 10.1101/gr.229102 10.1038/nature10530 10.1038/nature11247 10.1038/s41467-018-04558-1 10.1073/pnas.0506580102 10.1016/j.cels.2015.12.004 10.1002/gepi.21758 10.1093/ije/dyv080 10.1002/gepi.21965 10.1038/s41588-018-0099-7 10.1186/1471-2105-12-77
Nature Communications; Wu Y, Murray GK et. al.

Feb 20th, 2021 - Genetic factors are recognized to contribute to peptic ulcer disease (PUD) and other gastrointestinal diseases, such as gastro-oesophageal reflux disease (GORD), irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD). Here, genome-wid...

Systematic Review and Meta-Analysis of Prophylactic Transarterial Embolization for High...
https://doi.org/10.1016/j.jvir.2020.12.005
Journal of Vascular and Interventional Radiology : JVIR; Chang JHE, Lye TJY et. al.

Feb 2nd, 2021 - The present systematic review determined the role of transarterial embolization (TAE) as a prophylactic treatment in bleeding peptic ulcers after initial successful endoscopic hemostasis. PubMed and Ovid Medline databases were searched from incept...

Cryo-EM structure of Helicobacter pylori urease with an inhibitor in the active site at...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801526
Nature Communications; Cunha ES, Chen X et. al.

Jan 12th, 2021 - Infection of the human stomach by Helicobacter pylori remains a worldwide problem and greatly contributes to peptic ulcer disease and gastric cancer. Without active intervention approximately 50% of the world population will continue to be infecte...

see more →

News  111 results

Large prospective trial offers reassurance for long-term PPI use
https://www.mdedge.com/gihepnews/article/205801/upper-gi-tract/large-prospective-trial-offers-reassurance-long-term-ppi-use/page/0/1?channel=347

Aug 2nd, 2019 - Most patients in the trial (78%) were male, and 23% were current smokers. Smaller proportions of the population were taking an NSAID (5%) and/or had a history of peptic ulcer disease (2.

July 2019 - Question 2
https://www.mdedge.com/gihepnews/article/203785/july-2019-question-2?channel=29259

Jun 28th, 2019 - Q2. Correct answer: C Rationale Oral iron, and not infusions, are associated with peptic ulcer disease.

Can acid suppression prevent recurrent idiopathic gastroduodenal ulcer bleeding?
https://www.mdedge.com/jcomjournal/article/202014/gastroenterology/can-acid-suppression-prevent-recurrent-idiopathic?channel=213
Doug Brunk

May 31st, 2019 - SAN DIEGO – Lansoprazole and famotidine are comparable for the prevention of recurrent ulcer bleeding in patients with a history of Helicobacter pylori–negative idiopathic bleeding ulcers, results from a double-blind, randomized trial showed. Howe.

DDSEP® 8 Quick Quiz Question 2
https://www.mdedge.com/gihepnews/article/197788/ddsepr-8-quick-quiz-question-2

Mar 29th, 2019 - Critique: Factors raising suspicion for Zollinger-Ellison syndrome include recurrent peptic ulcer disease, multiple ulcers, post-bulbar ulcer, non-H. pylori/non-NSAID-related duodenal ulcer, diarrhea, erosive esophagitis, and family or personal hi.

April 2019 - Question 2
https://www.mdedge.com/gihepnews/article/197788/april-2019-question-2?channel=29259

Mar 29th, 2019 - Critique: Factors raising suspicion for Zollinger-Ellison syndrome include recurrent peptic ulcer disease, multiple ulcers, post-bulbar ulcer, non-H. pylori/non-NSAID-related duodenal ulcer, diarrhea, erosive esophagitis, and family or personal hi.

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Patient Education  3 results see all →