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About 23,710 results

ALLMedicine™ Constipation Center

Research & Reviews  5,169 results

Opportunities for novel diagnostic and cell-based therapies for Hirschsprung disease.
https://doi.org/10.1016/j.jpedsurg.2021.10.049
Journal of Pediatric Surgery; Pan W, Goldstein AM et. al.

Dec 3rd, 2021 - Despite significant progress in our understanding of the etiology and pathophysiology of Hirschsprung disease (HSCR), early and accurate diagnosis and operative management can be challenging. Moreover, long-term morbidity following surgery, includ...

Effect of fecal microbiota transplantation in patients with slow transit constipation a...
https://doi.org/10.1186/s12967-021-03152-2 10.1016/0002-9343(92)90133-V 10.1089/jmf.2017.4117
Journal of Translational Medicine; Xie L, Xu C et. al.

Dec 3rd, 2021 - Fecal microbiota transplantation (FMT) is considered an effective treatment for slow transit constipation (STC); nevertheless, the mechanism remains unclear. In this study, eight patients with STC were selected according to the inclusion and exclu...

Conservative management of the colonic gallstone.
https://doi.org/10.1136/bcr-2021-243040
BMJ Case Reports; Hurst KV, Peiris GB et. al.

Dec 2nd, 2021 - A 74-year-old woman presents with a 7-day history of increasing lower abdominal pains and reduced bowel movements; resulting in absolute constipation.Twenty-four hours prior to admission she also had symptoms of nauseous and significant abdominal ...

Ovarian Cancer
http://emedicine.medscape.com/article/255771-overview

Dec 1st, 2021 - Practice Essentials Ovarian cancer is the most common cause of cancer death from gynecologic tumors in the United States. Malignant ovarian lesions include primary lesions arising from normal structures within the ovary and secondary lesions from ...

Fecaloma - A Common Problem, Uncommon Dimensions.
https://www.ncbi.nlm.nih.gov/pubmed/34846372
Rhode Island Medical Journal (2013); Nahar R, Fernandes D et. al.

Dec 1st, 2021 - Chronic constipation and fecal impaction are common in older individuals but can also be found in younger patients with cognitive and psychiatric illnesses. The diagnosis of fecal impaction and, the assessment of severity are best performed clinic...

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Guidelines  16 results

My Treatment Approach to Multiple System Atrophy.
https://doi.org/10.1016/j.mayocp.2020.10.005
Mayo Clinic Proceedings; Coon EA, Ahlskog JE

Mar 7th, 2021 - Multiple system atrophy (MSA) is a neurodegenerative disorder primarily characterized by autonomic failure plus parkinsonism or cerebellar ataxia. The diagnosis may be challenging and is usually made at a tertiary care center. The long-term manage...

European society of neurogastroenterology and motility guidelines on functional constip...
https://doi.org/10.1111/nmo.13762
Neurogastroenterology and Motility : the Official Journal... Serra J, Pohl D et. al.

Nov 23rd, 2019 - Chronic constipation is a common disorder with a reported prevalence ranging from 3% to 27% in the general population. Several management strategies, including diagnostic tests, empiric treatments, and specific treatments, have been developed. Our...

Medical Management of Opioid-Induced Constipation.
https://doi.org/10.1001/jama.2019.15852
JAMA Rao VL, Micic D et. al.

Nov 5th, 2019 - Medical Management of Opioid-Induced Constipation.|2019|Rao VL,Micic D,Davis AM,|adverse effects,therapeutic use,therapeutic use,therapeutic use,analogs & derivatives,therapeutic use,therapeutic use,drug therapy,therapeutic use,

MASCC recommendations on the management of constipation in patients with advanced cancer.
https://doi.org/10.1007/s00520-019-05016-4
Supportive Care in Cancer : Official Journal of the Multi... Davies A, Leach C et. al.

Aug 10th, 2019 - The Palliative Care Study Group of the Multinational Association for Supportive Care in Cancer formed a subgroup to develop evidence-based recommendations on the management of constipation in patients with advanced cancer. These recommendations we...

Opioid-Induced Constipation (OIC) Guideline.
https://doi.org/10.1053/j.gastro.2018.10.044
Gastroenterology Crockett S, Greer KB et. al.

Nov 6th, 2018 - Opioid-Induced Constipation (OIC) Guideline.|2018|Crockett S,Greer KB,Sultan S,|adverse effects,chemically induced,diagnosis,drug therapy,physiopathology,drug effects,standards,adverse effects,therapeutic use,adverse effects,therapeutic use,advers...

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Drugs  2,446 results see all →

Clinicaltrials.gov  432 results

Effect of Transcutaneous Electroacupuncture on Functional Abdominal Bloating/Distension
https://clinicaltrials.gov/ct2/show/NCT04916106

Nov 25th, 2021 - Functional abdominal bloating/distension (FAB/D) is a common functional bowel disorder that lacks effective treatment options. Rome IV was introduced in 2016. Studies have shown that bloating may affect about 30% general population and 96% of pati...

FMT for Patients With IBS With Fecal and Mucosal Microbiota Assessment
https://clinicaltrials.gov/ct2/show/NCT03125564

Nov 25th, 2021 - Irritable bowel syndrome (IBS) is a common functional bowel disorder of the gastrointestinal tract affecting up to 20 percent of the adolescent and adult populations. It is characterised by abdominal pain, irregular bowel habits, altered stool con...

Endpoint Determination Study Protocol
https://clinicaltrials.gov/ct2/show/NCT03459482

Nov 24th, 2021 - The objective of this Endpoint Determination Study is to address key elements regarding a proposed larger clinical study design: Comparing different potential primary outcome measures Demonstrating that an exclusionary diet as determined by elevat...

Lactobacillus Rhamnosus in Prevention of Chemotherapy-related Diarrhoea
https://clinicaltrials.gov/ct2/show/NCT00197873

Nov 24th, 2021 - This is a prospective, multicenter, randomized, cross-over, double-blind, placebo-controlled study. Patients diagnosed with advanced colorectal cancer with overt distant metastases and who will receive chemotherapy consisting of capecitabine, oxal...

Linaclotide Safety and Efficacy in Pediatric Participants, 6 to 17 Years of Age, With Irritable Bowel Syndrome With Constipation (IBS-C) or Functional Constipation (FC)
https://clinicaltrials.gov/ct2/show/NCT04026113

Nov 19th, 2021 - The objective of LIN-MD-64 is to evaluate the safety and efficacy of 12 weeks of linaclotide therapy (72 μg daily) in comparison with placebo in pediatric participants, 6 to 17 years of age, who fulfill modified Rome III Criteria for Child/Adolesc...

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News  1,254 results

Sintilimab Combo Reduces Risk of Progression by 54% in EGFR-Mutated Nonsquamous NSCLC
https://www.onclive.com/view/sintilimab-combo-reduces-risk-of-progression-by-54-in-egfr-mutated-nonsquamous-nsclc

Nov 22nd, 2021 - The addition of sintilimab (Tyvyt) to a bevacizumab biosimilar (Byvasda) and pemetrexed/cisplatin resulted in a statistically significant and clinically meaningful improvement in progression-free survival (PFS) vs chemotherapy alone in patients wi...

Weight Loss Win for Weekly Injections of Novel Amylin Agent in Early Trial
https://www.medpagetoday.com/endocrinology/obesity/95757

Nov 18th, 2021 - The investigational long-acting amylin analogue cagrilintide (AM833) helped people with overweight or obesity, but no diabetes, shed pounds in a phase II trial. In the randomized trial, all doses of the novel once-weekly injectable treatment yield...

SL-172154 Shows Favorable Tolerability in Platinum-Resistant Ovarian Cancer
https://www.onclive.com/view/sl-172154-shows-favorable-tolerability-in-platinum-resistant-ovarian-cancer

Nov 17th, 2021 - The investigative agent SL-172154 (SIRPα-Fc-CD40L) was found to be well tolerated, with no dose-limiting toxicities (DLTs) observed, in patients with platinum-resistant ovarian cancer, according to findings from a phase 1 dose-escalation trial pre...

How to meet the challenges of managing patients with IBS
https://www.mdedge.com/familymedicine/article/248601/gastroenterology/how-meet-challenges-managing-patients-ibs
MDedge Family Medicine; Jose M. Villalon-Gomez, MD, MPH

Nov 12th, 2021 - Irritable bowel syndrome (IBS) continues to pose a diagnostic and therapeutic challenge to clinicians and patients—a challenge that arises from the varying manifestations of the condition, its complex pathophysiology, lack of effective treatment,.

FDA Grants Priority Review to Toripalimab for Nasopharyngeal Carcinoma
https://www.onclive.com/view/fda-grants-priority-review-to-toripalimab-for-nasopharyngeal-carcinoma

Nov 1st, 2021 - The FDA has accepted for review a biologics license application (BLA) for the use of toripalimab in combination with gemcitabine and cisplatin in the frontline treatment of patients with advanced recurrent or metastatic nasopharyngeal carcinoma, a...

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Patient Education  167 results see all →