×
About 9,444 results

ALLMedicine™ Leukemias Center

Research & Reviews  4,469 results

EBF1 and PAX5 control pro-B cell expansion via opposing regulation of the Myc gene.
https://doi.org/10.1182/blood.2020009564
Blood Somasundaram R, Jensen CT et. al.

Feb 23rd, 2021 - Genes encoding B lineage restricted transcription factors are frequently mutated in B-lymphoid leukemias, suggesting a close link between normal and malignant B-cell development. One of these transcription factors is Early B cell Factor 1 (EBF1), ...

Gene expression profiling identifies FLT3 mutation-like cases in wild-type FLT3 acute m...
https://doi.org/10.1371/journal.pone.0247093
PloS One; Mosquera Orgueira A, Peleteiro Raíndo A et. al.

Feb 16th, 2021 - FLT3 mutation is present in 25-30% of all acute myeloid leukemias (AML), and it is associated with adverse outcome. FLT3 inhibitors have shown improved survival results in AML both as upfront treatment and in relapsed/refractory disease. Curiously...

Neonatal Leukemia.
https://doi.org/10.1016/j.clp.2020.11.002
Clinics in Perinatology; Brown PA

Feb 15th, 2021 - Neonates are at risk for 3 major forms of leukemia in the first year of life: acute leukemia, juvenile myelomonocytic leukemia, and transient abnormal myelopoiesis associated with Down syndrome. These disorders are rare but generate interest due t...

Acute Leukemia in Infants.
https://doi.org/10.1007/s11912-021-01021-1 10.1182/blood.V96.1.24 10.1038/sj.leu.2402468 10.1182/blood-2005-07-3011 10.1200/jco.1999.17.2.445 10.1046/j.1365-2141.2002.03442.x 10.1002/pbc.25322 10.1038/leu.2011.267 10.1182/blood.v98.6.1714 10.1038/sj.leu.2401725 10.1038/363358a0 10.1158/1078-0432.Ccr-05-2861 10.1002/pbc.24132 10.1002/pbc.25311 10.1182/blood.V94.4.1209 10.1038/leu.2009.17 10.1038/leu.2013.280 10.3324/haematol.2014.122119 10.1111/j.1365-2141.2011.08851.x 10.3389/fped.2015.00037 10.1182/blood-2017-01-762336 10.1172/jci116978 10.1182/blood-2011-04-350017 10.1097/00043426-200201000-00002 10.1111/bjh.12041 10.1097/mop.0000000000000437 10.1016/j.tig.2005.10.002 10.1146/annurev-pathol-011811-132434 10.1038/nrc2253 10.1182/blood-2016-10-691428 10.1182/blood-2015-05-646398 10.3324/haematol.2012.067983 10.1182/blood-2003-02-0418 10.1038/ng765 10.3324/haematol.2014.106526 10.1038/leu.2012.223 10.1182/blood-2016-01-695551 10.1038/leu.2017.279 10.1016/s1470-2045(10)70090-5 10.1200/jco.2014.55.3628 10.1182/blood-2013-03-491621 10.1038/bmt.2014.246 10.1182/blood-2012-02-409813 10.1200/jco.2008.17.6065 10.1182/blood.2019004741 10.1038/leu.2014.172 10.1016/j.bbmt.2017.04.017 10.5863/1551-6776-19.4.262 10.1097/MPH.0b013e3181a6dec0 10.1038/sj.leu.2401818 10.1016/j.leukres.2018.11.015 10.1182/bloodadvances.2018016121 10.1016/j.celrep.2015.12.003 10.4155/fmc.13.214 10.1172/jci129126 10.1200/jco.2016.67.3301 10.1038/s41408-018-0117-0 10.1002/pbc.25953 10.1038/nm.4441 10.1182/blood.2019003293
Current Oncology Reports; Ibrahimova A, Pommert L et. al.

Feb 13th, 2021 - Infant leukemia is a rare, distinct subgroup of pediatric acute leukemias diagnosed in children under 1 year of age and characterized by unique, aggressive biology. Here, we review its clinical presentation, underlying molecular biology, current t...

Antileukemic efficacy of a potent artemisinin combined with sorafenib and venetoclax.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876886
Blood Advances; Moses BS, McCullough S et. al.

Feb 9th, 2021 - Artemisinins are active against human leukemia cell lines and have low clinical toxicity in worldwide use as antimalarials. Because multiagent combination regimens are necessary to cure fully evolved leukemias, we sought to leverage our previous f...

see more →

Guidelines  19 results

Acute Myeloid Leukemia - AML | ARUPConsult Lab Test Selection
https://arupconsult.com/content/acute-myeloid-leukemia

Jun 30th, 2019 - Acute myeloid leukemias (AMLs) are a heterogeneous group of disorders characterized by the clonal expansion of myeloid blasts (eg, undifferentiated myeloid precursors) in the peripheral blood, bone marrow, and/or other tissues, which results in im...

Acute Myeloid Leukemia, Version 3.2019, NCCN Clinical Practice Guidelines in Oncology
https://jnccn.org/view/journals/jnccn/17/6/article-p721.xml
Journal of the National Comprehensive Cancer Network;

Jun 14th, 2019 - Acute myeloid leukemia (AML) is the most common form of acute leukemia among adults and accounts for the largest number of annual deaths due to leukemias in the United States. Recent advances have resulted in an expansion of treatment options for ...

23rd Annual International Congress on Hematologic Malignancies®: Focus on Leukemias, Lymphomas, and Myeloma
https://www.gotoper.com/conferences/hem/meetings/23rd-international-congress-on-hematologic-malignancies-focus-on-leukemias-lymphomas-and-myeloma

Feb 27th, 2019 - Now in its 23rd year, the annual International Congress on Hematologic Malignancies®: Focus on Leukemias, Lymphomas, and Myeloma provides practitioners who manage hematologic malignancies the practical tools to translate emerging data into the bes...

Hematology Quality Metrics
http://www.hematology.org/Clinicians/Guidelines-Quality/503.aspx
Allen, S.

Feb 20th, 2018 - These clinical performance measures are designed for individual quality improvement. Some of the measures may also be appropriate for accountability if appropriate sample sizes and implementation rules are achieved.

see more →

Drugs  39 results see all →

Clinicaltrials.gov  4,671 results

EBF1 and PAX5 control pro-B cell expansion via opposing regulation of the Myc gene.
https://doi.org/10.1182/blood.2020009564
Blood Somasundaram R, Jensen CT et. al.

Feb 23rd, 2021 - Genes encoding B lineage restricted transcription factors are frequently mutated in B-lymphoid leukemias, suggesting a close link between normal and malignant B-cell development. One of these transcription factors is Early B cell Factor 1 (EBF1), ...

Gene expression profiling identifies FLT3 mutation-like cases in wild-type FLT3 acute m...
https://doi.org/10.1371/journal.pone.0247093
PloS One; Mosquera Orgueira A, Peleteiro Raíndo A et. al.

Feb 16th, 2021 - FLT3 mutation is present in 25-30% of all acute myeloid leukemias (AML), and it is associated with adverse outcome. FLT3 inhibitors have shown improved survival results in AML both as upfront treatment and in relapsed/refractory disease. Curiously...

Neonatal Leukemia.
https://doi.org/10.1016/j.clp.2020.11.002
Clinics in Perinatology; Brown PA

Feb 15th, 2021 - Neonates are at risk for 3 major forms of leukemia in the first year of life: acute leukemia, juvenile myelomonocytic leukemia, and transient abnormal myelopoiesis associated with Down syndrome. These disorders are rare but generate interest due t...

Acute Leukemia in Infants.
https://doi.org/10.1007/s11912-021-01021-1 10.1182/blood.V96.1.24 10.1038/sj.leu.2402468 10.1182/blood-2005-07-3011 10.1200/jco.1999.17.2.445 10.1046/j.1365-2141.2002.03442.x 10.1002/pbc.25322 10.1038/leu.2011.267 10.1182/blood.v98.6.1714 10.1038/sj.leu.2401725 10.1038/363358a0 10.1158/1078-0432.Ccr-05-2861 10.1002/pbc.24132 10.1002/pbc.25311 10.1182/blood.V94.4.1209 10.1038/leu.2009.17 10.1038/leu.2013.280 10.3324/haematol.2014.122119 10.1111/j.1365-2141.2011.08851.x 10.3389/fped.2015.00037 10.1182/blood-2017-01-762336 10.1172/jci116978 10.1182/blood-2011-04-350017 10.1097/00043426-200201000-00002 10.1111/bjh.12041 10.1097/mop.0000000000000437 10.1016/j.tig.2005.10.002 10.1146/annurev-pathol-011811-132434 10.1038/nrc2253 10.1182/blood-2016-10-691428 10.1182/blood-2015-05-646398 10.3324/haematol.2012.067983 10.1182/blood-2003-02-0418 10.1038/ng765 10.3324/haematol.2014.106526 10.1038/leu.2012.223 10.1182/blood-2016-01-695551 10.1038/leu.2017.279 10.1016/s1470-2045(10)70090-5 10.1200/jco.2014.55.3628 10.1182/blood-2013-03-491621 10.1038/bmt.2014.246 10.1182/blood-2012-02-409813 10.1200/jco.2008.17.6065 10.1182/blood.2019004741 10.1038/leu.2014.172 10.1016/j.bbmt.2017.04.017 10.5863/1551-6776-19.4.262 10.1097/MPH.0b013e3181a6dec0 10.1038/sj.leu.2401818 10.1016/j.leukres.2018.11.015 10.1182/bloodadvances.2018016121 10.1016/j.celrep.2015.12.003 10.4155/fmc.13.214 10.1172/jci129126 10.1200/jco.2016.67.3301 10.1038/s41408-018-0117-0 10.1002/pbc.25953 10.1038/nm.4441 10.1182/blood.2019003293
Current Oncology Reports; Ibrahimova A, Pommert L et. al.

Feb 13th, 2021 - Infant leukemia is a rare, distinct subgroup of pediatric acute leukemias diagnosed in children under 1 year of age and characterized by unique, aggressive biology. Here, we review its clinical presentation, underlying molecular biology, current t...

Antileukemic efficacy of a potent artemisinin combined with sorafenib and venetoclax.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876886
Blood Advances; Moses BS, McCullough S et. al.

Feb 9th, 2021 - Artemisinins are active against human leukemia cell lines and have low clinical toxicity in worldwide use as antimalarials. Because multiagent combination regimens are necessary to cure fully evolved leukemias, we sought to leverage our previous f...

see more →

News  245 results

The Next 'Big Thing' for Blood Cancers Featured at ASH 2019
https://www.staging.medscape.com/viewarticle/921942

Dec 6th, 2019 - The prospect of an "off-the-shelf" product, rather than one that needs to be grown individually for each patient, is a "very exciting" proposition, say experts discussing new data that will be presented at the forthcoming American Society of Hemat...

The Next 'Big Thing' for Blood Cancers Featured at ASH 2019
https://www.medscape.com/viewarticle/921942

Dec 6th, 2019 - The prospect of an "off-the-shelf" product, rather than one that needs to be grown individually for each patient, is a "very exciting" proposition, say experts discussing new data that will be presented at the forthcoming American Society of Hemat...

Federal Health Care Cancer Data Trends 2019
https://www.mdedge.com/fedprac/article/209596/federal-health-care-cancer-data-trends-2019?channel=167

Oct 7th, 2019 - Click here to access Federal Health Care Cancer Data Trends 2019 Table of Contents Introduction Cancer in the VA: The Big Picture Hepatocellular Carcinoma Prostate Cancer Multiple Myeloma Lung Cancer in the VA at a National Level Lung Cancer – Reg.

Leukemia Federal Health Care Data Trends
https://www.mdedge.com/fedprac/avaho/article/208837/oncology/leukemia-federal-health-care-data-trends?channel=263
Joao L. Ascensao, MD, PhD, FACP

Sep 25th, 2019 - (function(n){var r="_ion_ionizer",t=n. getElementsByTagName("script"),i;t=t[t.

see more →

Patient Education  1 results see all →