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About 58,285 results

ALLMedicine™ Tuberculosis Center

Research & Reviews  21,388 results

Sociodemographic Characteristics, Comorbidities, and Mortality Among Persons Diagnosed ...
https://doi.org/10.1001/jamanetworkopen.2021.36853
JAMA Network Open; Nabity SA, Han E et. al.

Dec 4th, 2021 - Tuberculosis (TB) and COVID-19 are respiratory diseases that disproportionately occur among medically underserved populations; little is known about their epidemiologic intersection. To characterize persons diagnosed with TB and COVID-19 in Califo...

BCG vaccination strategies against tuberculosis: updates and perspectives.
https://doi.org/10.1080/21645515.2021.2007711
Human Vaccines & Immunotherapeutics; Qu M, Zhou X et. al.

Dec 4th, 2021 - Bacillus Calmette-Guérin (BCG) is the only licensed vaccine against tuberculosis (TB). However, BCG has variable efficacy and cannot completely prevent TB infection and transmission. Therefore, the worldwide prevalence of TB calls for urgent devel...

Has the Time Come for Systematic Therapeutic Drug Monitoring of First-line and WHO Grou...
https://doi.org/10.1097/FTD.0000000000000948
Therapeutic Drug Monitoring; Lemaitre F

Dec 4th, 2021 - Tuberculosis (TB) is a major global health issue, with approximately 10 million people being infected each year, and is the leading cause of mortality from infectious disease, with 1.5 million deaths a year. Optimal TB treatment requires a combina...

PREVAIL VIIIa: Evaluation of Latent Tuberculosis Infection Screening Methods in People Living With Retroviral Infection in Liberia
https://clinicaltrials.gov/ct2/show/NCT04926922

Dec 3rd, 2021 - Despite the high burden of disease attributable to tuberculosis (TB) in Liberia and concerns about its effect on HIV disease, screening for latent TB infection (LTBI) among people living with HIV is not routinely performed in the country. This is ...

Antiretroviral therapy timing impacts latent tuberculosis infection reactivation in a t...
https://doi.org/10.1172/JCI153090
The Journal of Clinical Investigation; Sharan R, Ganatra SR et. al.

Dec 3rd, 2021 - Studies using the nonhuman primate model of M. tuberculosis /Simian Immunodeficiency Virus co-infection have revealed protective CD4+ T cell-independent immune responses that suppress LTBI reactivation. In particular, chronic immune activation rat...

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Guidelines  24 results

Multisystem inflammatory syndrome in an adult with SARS-CoV-2 infection.
https://doi.org/10.1016/j.arbres.2020.03.021
European Heart Journal. Cardiovascular Imaging; Chowdhary A, Joy E et. al.

Sep 6th, 2020 - New evidence and knowledge about the clinical management of drug-resistant tuberculosis (TB) in the last 3 years, makes it necessary to update the recent guideline published by SEPAR in 2017, mainly in relation to new diagnostic methods, drug clas...

2019 update of the European AIDS Clinical Society Guidelines for treatment of people li...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754379
HIV Medicine; Ryom L, Cotter A et. al.

Sep 5th, 2020 - The European AIDS Clinical Society (EACS) Guidelines cover key aspects of HIV management with major updates every two years. The 2019 Guidelines were extended with a new section focusing on drug-drug interactions and other prescribing issues in pe...

Collaborative Ocular Tuberculosis Study Consensus Guidelines on the Management of Tuber...
https://doi.org/10.1016/j.ophtha.2020.06.052
Ophthalmology Agrawal R, Testi I et. al.

Jul 1st, 2020 - The Collaborative Ocular Tuberculosis Study (COTS), supported by the International Ocular Inflammation Society, International Uveitis Study Group, and Foster Ocular Immunological Society, set up an international, expert-led consensus project to de...

Collaborative Ocular Tuberculosis Study Consensus Guidelines on the Management of Tuber...
https://doi.org/10.1016/j.ophtha.2020.01.008
Ophthalmology Agrawal R, Testi I et. al.

Mar 3rd, 2020 - An international, expert-led consensus initiative organized by the Collaborative Ocular Tuberculosis Study (COTS), along with the International Ocular Inflammation Society and the International Uveitis Study Group, systematically developed evidenc...

Improving Quality of Patient Data for Treatment of Multidrug- or Rifampin-Resistant Tub...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7045826
Emerging Infectious Diseases; Campbell JR, Falzon D et. al.

Jan 11th, 2020 - International policy for treatment of multidrug- and rifampin-resistant tuberculosis (MDR/RR TB) relies largely on individual patient data (IPD) from observational studies of patients treated under routine conditions. We prepared guidance on which...

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Drugs  327 results see all →

Clinicaltrials.gov  465 results

PREVAIL VIIIa: Evaluation of Latent Tuberculosis Infection Screening Methods in People Living With Retroviral Infection in Liberia
https://clinicaltrials.gov/ct2/show/NCT04926922

Dec 3rd, 2021 - Despite the high burden of disease attributable to tuberculosis (TB) in Liberia and concerns about its effect on HIV disease, screening for latent TB infection (LTBI) among people living with HIV is not routinely performed in the country. This is ...

A Study of Guselkumab in Participants With Active Lupus Nephritis
https://clinicaltrials.gov/ct2/show/NCT04376827

Dec 3rd, 2021 - Guselkumab is a monoclonal antibody (mAb) that binds to human interleukin (IL)-23 with high affinity and blocks binding of extracellular IL-23 to cell surface IL-23 receptor, inhibiting IL 23 specific intracellular signaling and subsequent activat...

Characterization of Tissue-Specific Immune Responses to Bronchoscopic Instillation of Mycobacterial Antigens Into the Human Lung
https://clinicaltrials.gov/ct2/show/NCT05027958

Dec 3rd, 2021 - We propose a pilot study in which we employ directed bronchoscopic instillation of Mycobacterium tuberculosis (Mtb)-derived Purified Protein Derivative (PPD) to evaluate local airway immune response in adults with or without latent tuberculosis in...

Pharmacokinetic Properties of Antiretroviral and Anti-Tuberculosis Drugs During Pregnancy and Postpartum
https://clinicaltrials.gov/ct2/show/NCT04518228

Nov 24th, 2021 - This study will evaluate the pharmacokinetic (PK) properties of antiretroviral (ARV) and anti-tuberculosis (TB) drugs administered during pregnancy and postpartum. This study is comprised of five components which in turn are comprised of arms spec...

Influence of Filarial Infections on Tuberculosis Disease and Tuberculosis Vaccination in Cameroon
https://clinicaltrials.gov/ct2/show/NCT04547738

Nov 23rd, 2021 - Filarial nematodes modulate the host immune response to promote regulatory and T helper type 2 immune responses, which were shown to influence concomitant infections. Indeed, several studies showed that increased susceptibility and worsened diseas...

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News  1,089 results

From Cows to COVID: The Spooky Origins of Vaccines
https://www.medscape.com/viewarticle/962851

Nov 12th, 2021 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. Back in the 18th century, it was a wonder how anyone ever survived a trip to the doctor. Many didn't. England's drug stores were stocked with bull...

Navigating OpenNotes: Advice From an Oncologist Who Survived Cancer
https://www.medscape.com/viewarticle/961646

Nov 3rd, 2021 - This transcript has been edited for clarity. Hello. This is Dr Mark Lewis for Medscape. I'd like talk to you about a hot topic: exactly how and when patients with cancer receive their test results. There are essentially two groups: those who lobby...

CDC: Mood Disorders Increase Risk for Severe COVID-19
https://www.medscape.com/viewarticle/961805

Oct 28th, 2021 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. The CDC says people with certain mental health conditions could have a higher risk of more severe COVID-19, which could lead to a need for hospita...

Limited or No Access to Essential Diagnostic Tools for Many in Middle- and Low-Income Countries
https://www.medscape.com/viewarticle/960748

Oct 13th, 2021 - (Reuters Health) - Two new reports highlight the lack of essential diagnostic tools in middle- and low- income countries and suggest that closing the diagnostics gap could save millions of lives annually. In one study, a panel of experts forming T...

Cavitary Lung Lesion in a Tuberculosis-Negative Patient
https://www.mdedge.com/fedprac/article/247212/pulmonology/cavitary-lung-lesion-tuberculosis-negative-patient
LT Michael C. Harding, MD, USPHS, Capt Steven J. Gibson, MD, USAF et. al.

Oct 8th, 2021 - A patient with worsening chronic cough, shortness of breath, and hemoptysis tested negative for tuberculosis; but a chest computed tomography scan showed an upper left lobe cavitary lesion. A 71-year-old, currently homeless male veteran with a 29.

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Patient Education  21 results see all →