About 1,373 results

ALLMedicine™ Nicotine Addiction Center

Research & Reviews  447 results

Nicotine-mediated OTUD3 downregulation inhibits VEGF-C mRNA decay to promote lymphatic ...
Nature Communications; Wang M, Li Y et. al.

Dec 3rd, 2021 - Nicotine addiction and the occurrence of lymph node spread are two major significant factors associated with esophageal cancer's poor prognosis; however, nicotine's role in inducing lymphatic metastasis of esophageal cancer remains unclear. Here w...

The 1988 U.S. Surgeon General's report 'Nicotine Addiction': How well has it stood up t...
Addiction (Abingdon, England); West R, Cox S

Nov 25th, 2021 - The 1988 U.S. Surgeon General's Report titled 'Nicotine Addiction' was a comprehensive treatise setting out the evidence that tobacco is addictive and showing that nicotine lies at the heart of this addiction. It likened tobacco to drugs such as c...

Genes identified in rodent studies of alcohol intake are enriched for heritability of h...
Alcoholism, Clinical and Experimental Research; Huggett SB, Johnson EC et. al.

Nov 10th, 2021 - Rodent paradigms and human genome-wide association studies (GWAS) on drug use have the potential to provide biological insight into the pathophysiology of addiction. Using GeneWeaver, we created rodent alcohol and nicotine gene-sets derived from 1...

Clonidine Toxicity

Oct 21st, 2021 - Practice Essentials Clonidine is a central alpha-agonist that is used as an antihypertensive agent. Other reported clinical uses include treatment of opiate and alcohol withdrawal [1] and control of atrial fibrillation with a rapid ventricular rat...

Decreased mitochondrial DNA copy number in nerve cells and the hippocampus during nicot...
Ecotoxicology and Environmental Safety; Wang H, Chen H et. al.

Oct 1st, 2021 - Cigarette smoke is a harmful air pollutant and nicotine dependence is the essential cause of the tobacco epidemic. Since mitochondrial abnormalities are associated with substance addiction, in this work we used mitochondrial DNA (mtDNA) copy numbe...

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Clinicaltrials.gov  21 results

Cytisine Compared to Combination NRT in Relapsed Smokers

Sep 28th, 2021 - Cigarette smoking is a causative factor in the development of coronary heart disease (CHD), and is the most dangerous form of tobacco use. Effective treatments for smoking cessation exist but relapse to cigarette smoking is common, principally due...

Memantine Hydrochloride in Helping Cancer Survivors Stop Smoking

Sep 28th, 2021 - OBJECTIVES: Primary Estimate participation, accrual, adherence, and retention of cancer survivors who smoke and are randomized to receive memantine (memantine hydrochloride) (10 mg twice daily) or a matching placebo for 12 weeks. Estimate the self...

Circuitry-Guided Smoking Cessation in Schizophrenia

Aug 5th, 2021 - Neuroimaging studies suggest that high rate of smoking in patients with schizophrenia may be due to an overlap of nicotine addiction related circuitries and schizophrenia related circuitries, such that schizophrenia impact some of the same circuit...

E-cigarette Nicotine Study

Jun 16th, 2021 - Background Use of Electronic Nicotine Delivery Systems (ENDS) has increased substantially in the past decade, and nearly 70% of ENDS users also smoke cigarettes (i.e., dual users). There is evidence that ENDS can be used as an effective smoking ce...

Vaping THC From Electronic Cigarettes

Apr 30th, 2021 - Electronic cigarettes (e-cigarettes) have proliferated at a rapid rate since their introduction into the US market in 2007, and their use as a form of nicotine delivery far outpaced the science base. Although the design of these devices continues ...

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News  78 results

Does TikTok Push Vaping?

Jul 26th, 2021 - Videos posted on TikTok depicting e-cigarettes mostly make vaping look cool and fun, researchers found. An analysis of 808 videos, selected using hashtags on vaping, indicated that 63% portrayed e-cigarettes in a positive light, whereas only 13% w...

Thumbs Up for Vax Mixing; New Lockdowns Over Delta; Juul Settles for $40M

Jun 29th, 2021 - Note that some links may require registration or subscription. Preliminary research found that mixing doses of Pfizer and AstraZeneca's COVID-19 vaccines produced high levels of antibodies and immune cells. (New York Times) In a Gallup poll, 29% o...

FDA Must Do More to Stop Youth Vaping, House Members Say

Jun 23rd, 2021 - WASHINGTON -- The FDA should be doing more to stop kids from getting addicted to e-cigarettes, House members told FDA Acting Commissioner Janet Woodcock, MD, at a hearing on youth vaping on Wednesday. "I just want to make sure America understands,...

COVID Vax Platform Expands; A Devil of a Cancer Link; Talking About the C(ure)-Word

Jun 2nd, 2021 - The same molecular platform that led to effective vaccines against the novel coronavirus -- messenger RNA -- has begun expanding into other therapeutic areas, including cancer. (CNN) Men with a family history of prostate cancer should begin screen...

Cigarette smoking is associated with prefrontal function in patients with schizophrenia
Jake Remaly

Feb 21st, 2020 - Patients with schizophrenia have decreased chronnectomic density in the dorsolateral prefrontal cortex, compared with healthy controls, and cigarette smoking in patients with schizophrenia may be associated with a degree of preserved function in t.

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Patient Education  3 results see all →