About 9,530 results

ALLMedicine™ Gout Center

Research & Reviews  2,622 results

Serum Urate as a Proposed Surrogate Outcome Measure in Gout Trials: From the OMERACT Wo...
Seminars in Arthritis and Rheumatism; Morillon MB, Christensen R et. al.

Nov 30th, 2021 - Serum urate (SU) is the most common primary efficacy outcome in trials of urate-lowering therapies for gout. Despite this, it is not formally considered a validated surrogate outcome. In this paper we will outline the definitions of biomarkers and...

Characteristics of monosodium urate crystal deposition in the foot in the different sta...
International Journal of Rheumatic Diseases; Zhang Y, Di A et. al.

Nov 27th, 2021 - To compare the characteristics of monosodium urate (MSU) crystal deposition at specific anatomical sites of the foot detected by dual-energy computed tomography in patients with different stages of gout. This study included 101 patients with gout,...

Gout during the SARS-CoV-2 pandemic: increased flares, urate levels and functional impr...
Clinical Rheumatology; García-Maturano JS, Torres-Ordaz DE et. al.

Nov 26th, 2021 - Gout is the most common inflammatory arthritis, but was not considered in most COVID-19 and rheumatic diseases reports. Our aim was to describe changes in clinical data, treatment, function and quality of life for gout patients during COVID-19 pan...

Randomised controlled trial targeting habit formation to improve medication adherence t...
BMJ Open; Fontanet CP, Choudhry NK et. al.

Nov 26th, 2021 - Medication adherence for patients with chronic conditions such as gout, a debilitating form of arthritis that requires daily medication to prevent flares, is a costly problem. Existing interventions to improve medication adherence have only been m...

Role of diet in hyperuricemia and gout.
Best Practice & Research. Clinical Rheumatology; Danve A, Sehra ST et. al.

Nov 23rd, 2021 - Gout is the most common form of inflammatory arthritis, affecting 41 million adults worldwide. The global burden of gout has been increasing over the last three decades, yet its management remains suboptimal. The primary aim of this manuscript is ...

see more →

Guidelines  7 results

2020 American College of Rheumatology Guideline for the Management of Gout.
Arthritis & Rheumatology (Hoboken, N.J.); FitzGerald JD, Dalbeth N et. al.

May 12th, 2020 - To provide guidance for the management of gout, including indications for and optimal use of urate-lowering therapy (ULT), treatment of gout flares, and lifestyle and other medication recommendations. Fifty-seven population, intervention, comparat...

2018 updated European League Against Rheumatism evidence-based recommendations for the ...
Annals of the Rheumatic Diseases; Richette P, Doherty M et. al.

Jun 7th, 2019 - Although gout is the most common inflammatory arthritis, it is still frequently misdiagnosed. New data on imaging and clinical diagnosis have become available since the first EULAR recommendations for the diagnosis of gout in 2006. This prompted a...

The British Society for Rheumatology Guideline for the Management of Gout.
Rheumatology (Oxford, England); Hui M, Carr A et. al.

May 27th, 2017 - The British Society for Rheumatology Guideline for the Management of Gout.|2017|Hui M,Carr A,Cameron S,Davenport G,Doherty M,|diet therapy,drug therapy,therapy,therapeutic use,

ACR Appropriateness Criteria® Chronic Extremity Joint Pain-Suspected Inflammatory Arthr...
Journal of the American College of Radiology : JACR; , Jacobson JA et. al.

May 6th, 2017 - Evaluation for suspected inflammatory arthritis as a cause for chronic extremity joint pain often relies on imaging. This review first discusses the characteristic osseous and soft tissue abnormalities seen with inflammatory arthritis and how they...

Diagnosis of Acute Gout: A Clinical Practice Guideline From the American College of Phy...
Annals of Internal Medicine; Qaseem A, McLean RM et. al.

Nov 2nd, 2016 - The American College of Physicians (ACP) developed this guideline to present the evidence and provide clinical recommendations on the diagnosis of gout. This guideline is based on a systematic review of published studies on gout diagnosis, identif...

see more →

Drugs  404 results see all →

Clinicaltrials.gov  118 results

Evaluation of Efficacy and Safety of AR882 in Gout Patients

Nov 15th, 2021 - This study will assess the serum uric acid lowering effect and safety of AR882 in gout patients at two doses compared to placebo over 12 weeks.

Study of Verinurad in Heart Failure With Preserved Ejection Fraction

Nov 15th, 2021 - Evidence shows independent associations between hyperuricaemia and the risk of cardio-renal conditions, including heart failure (HF). Serum uric acid (sUA) is also a strong prognostic factor and correlates with other markers of poor prognosis in H...

Anakinra vs. Steroids for the Treatment of Gout Attacks in Patients With Renal Disease (ASGARD): A Feasibility Study

Nov 12th, 2021 - Gout is a common condition that affects 1 in 40 people in the UK. It causes painful "attacks" of joint swelling, redness and tenderness, mostly affecting the foot, ankle, knee, hand and wrist. It is common in people with kidney disease, who also t...

Colchicine for Patients With Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement

Oct 22nd, 2021 - Transcatheter aortic valve implantation (TAVI) is a well-established alternative to surgical aortic valve replacement for the treatment of patients with symptomatic severe aortic stenosis. While peri-procedural complications such as stroke, vascul...

Comparison of the Effectiveness of USG and Palpation Guidance Steroid Injection in Patients With Plantar Fasciitis

Oct 20th, 2021 - It is planned to enroll 60 (sixty) patients in the study. Patients diagnosed with plantar fasciitis, between the ages of 18-75, who have failed conservative treatment (stretching exercises, non-steroidal anti-inflammatory drugs and heel pads) for ...

see more →

News  635 results

Allopurinol Proves Noninferior to Febuxostat for Gout Relief

Nov 11th, 2021 - Allopurinol may finally start to get the respect that many rheumatologists feel it deserves as a first-line urate-lowering treatment for gout, following results of a randomized trial showing that it was noninferior to febuxostat both in the overal...

Two Swings, Two Misses With Colchicine, Vascepa in COVID-19

Aug 31st, 2021 - The anti-inflammatory agents colchicine and icosapent ethyl (Vascepa; Amarin) failed to provide substantial benefits in separate randomized COVID-19 trials. Both were reported at the European Society of Cardiology (ESC) Congress 2021. The open-lab...

Identifying potential risks factors for PsA

Aug 28th, 2021 - Key clinical point: A previous diagnosis of gout, uveitis, metabolic and lifestyle factors like obesity, alcohol consumption, and infections like pharyngitis and skin infections were potential risk factors for psoriatic arthritis (PsA), whereas st.

Novel Antidepressant Shines in Phase 2 Trial, but FDA Has Issues With Its NDA

Aug 11th, 2021 - Although a novel investigational drug that combines dextromethorphan and bupropion (AXS-05, Axsome Therapeutics) met its primary and key secondary endpoints in a phase 2 trial of patients with treatment-resistant depression (TRD), the US Food and ...

Western, Proinflammatory Diets Are Major Drivers of Gout Risk

Jun 16th, 2021 - Diets high in red meats, saturated fats, and sugars, relative to diets dominated by fruits, vegetables, and legumes, are associated with an increased risk of gout independent of an underlying genetic risk, according to independent sets of data pre...

see more →

Patient Education  26 results see all →