About 57,548 results

ALLMedicine™ Multiple Sclerosis Center

Research & Reviews  18,962 results

P038 Ozanimod First-Dose Cardiac Effects in Patients with Moderately to Severely Active...
The American Journal of Gastroenterology; Millie L, Raymond C et. al.

Dec 2nd, 2021 - P038 Ozanimod First-Dose Cardiac Effects in Patients with Moderately to Severely Active Ulcerative Colitis and Relapsing Multiple Sclerosis.|2021|Millie L,Raymond C,Jonathan C,Marc P,Ashwini P,|

Topiramate-induced severe electrolyte abnormalities and hypernatremia leading to centra...
BMJ Case Reports; Muaddi L, Osman O et. al.

Dec 2nd, 2021 - Central pontine myelinolysis (CPM) develops due to acute hypernatremia from a normal baseline serum sodium in the setting of electrolyte abnormalities induced by topiramate use. Topiramate is a commonly used medication with several indications inc...

Dimethyl fumarate treatment restrains the antioxidative capacity of T cells to control ...
Brain : a Journal of Neurology; Liebmann M, Korn L et. al.

Dec 2nd, 2021 - Dimethyl fumarate, an approved treatment for relapsing-remitting multiple sclerosis, exerts pleiotropic effects on immune cells as well as CNS resident cells. Here, we show that dimethyl fumarate exerts a profound alteration of the metabolic profi...

Charting a global research strategy for progressive MS-An international progressive MS ...
Multiple Sclerosis (Houndmills, Basingstoke, England); Thompson AJ, Carroll W et. al.

Dec 2nd, 2021 - Progressive forms of multiple sclerosis (MS) affect more than 1 million individuals globally. Recent approvals of ocrelizumab for primary progressive MS and siponimod for active secondary progressive MS have opened the therapeutic door, though res...

Effects of home-based virtual reality telerehabilitation system in people with multiple...
Journal of Telemedicine and Telecare; Pagliari C, Di Tella S et. al.

Dec 2nd, 2021 - Multiple sclerosis is an inflammatory and neurodegenerative disorder of the central nervous system that can lead to severe motor disability. The aim of this study was to verify the health care effects of an integrated telerehabilitation approach i...

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Guidelines  15 results

Vision Problems in Multiple Sclerosis.
Archives of Physical Medicine and Rehabilitation; Costa SL, Pandey K et. al.

Sep 29th, 2020 - Vision Problems in Multiple Sclerosis.|2020|Costa SL,Pandey K,Hrdina J,Rondon M,Devos H,|

Serum neurofilament light as a biomarker in progressive multiple sclerosis.
Neurology Kapoor R, Smith KE et. al.

Jul 18th, 2020 - There is an unmet need in multiple sclerosis (MS) therapy for treatments to stop progressive disability. The development of treatments may be accelerated if novel biomarkers are developed to overcome the limitations of traditional imaging outcomes...

Practical Sleep Information for People With Multiple Sclerosis.
Archives of Physical Medicine and Rehabilitation; Siengsukon C, Karahan AY et. al.

May 14th, 2020 - Practical Sleep Information for People With Multiple Sclerosis.|2020|Siengsukon C,Karahan AY,Strober L,|

Immunization and multiple sclerosis: Recommendations from the French multiple sclerosis...
Multiple Sclerosis and Related Disorders; Lebrun C, Vukusic S et. al.

Jun 5th, 2019 - To establish recommendations on immunization for patients with multiple sclerosis (MS) BACKGROUND: Vaccines have been suspected in the past to trigger MS and relapses. With the extension of the immunoactive treatment arsenal, other concerns have b...

ESPEN guideline clinical nutrition in neurology.
Clinical Nutrition (Edinburgh, Scotland); Burgos R, Bretón I et. al.

Dec 25th, 2017 - Neurological diseases are frequently associated with swallowing disorders and malnutrition. Moreover, patients with neurological diseases are at increased risk of micronutrient deficiency and dehydration. On the other hand, nutritional factors may...

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Drugs  339 results see all →

Clinicaltrials.gov  834 results

Gene Expression in Chronic Venous Leg Ulcers

Nov 25th, 2021 - Chronic Venous Disease (CVD) is a widespread clinical condition widely spread in the western countries, with a prevalence ranging from 10% in adults younger than 30 years of age to nearly 80% for individuals >70 years of age. CVD clinical manifest...

Study to Evaluate the Efficacy, Safety, and Tolerability of IMU-838 in Patients With Relapsing Multiple Sclerosis

Nov 25th, 2021 - This study will be a multicenter, randomized, double-blind, placebo-controlled study with a blinded Main Treatment Period (MT) and an Open Label Period (OLE) to evaluate the efficacy, safety, and tolerability of IMU-838 in adult patients with RMS....

Manganese-Enhanced Magnetic Resonance Imaging in Healthy Volunteers and People With Multiple Sclerosis

Nov 25th, 2021 - Objective The original goals of this pilot study were to assess whether: (1) manganese-enhanced magnetic resonance imaging (MEMRI) using mangafodipir trisodium, a contrast agent that enters the intracellular compartment, can detect multiple sclero...

Non-inferiority Study of Ocrelizumab and Rituximab in Active Multiple Sclerosis

Nov 24th, 2021 - The DanNORMS study will include patients with active multiple sclerosis aged 18-65 years. Patients will be randomized in a 2:1 ratio to either rituximab or ocrelizumab. The study duration is 24 months, and patients can continue in an extension pha...

Exploring the Efficacy and Safety of Siponimod in Patients With Secondary Progressive Multiple Sclerosis (EXPAND)

Nov 23rd, 2021 - Evaluate the safety and efficacy of Siponimod (BAF312) versus placebo in a variable treatment duration in patients with secondary progressive multiple sclerosis (Core Part) followed by extended treatment with open-label BAF312 to obtain data on lo...

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News  2,812 results

Woman with history of difficulty walking

Nov 30th, 2021 - The patient has probably transitioned to the secondary progressive form of multiple sclerosis (MS). Four phenotypes have been identified in MS, with relapsing-remitting MS (RRMS) representing the most common and secondary progressive MS (SPMS) the.

Coffee and Cognitive Decline; Head Impact Injuries; Alzheimer's Gene Therapy?

Nov 30th, 2021 - Higher coffee consumption was tied to slower cognitive decline and less cerebral amyloid-beta accumulation over 126 months, an Australian study showed. (Frontiers in Aging Neuroscience) Physical activity may promote synaptic and cognitive resilien...

AI Spots Cognitive Decline; Vax Reactions in MS; When Cutting Opioids Harms Patients

Nov 23rd, 2021 - A deep learning model accurately detected cognitive decline from clinical notes up to 4 years before patients were diagnosed with mild cognitive impairment. (JAMA Network Open) Subjective sleep difficulties were associated with self-perceptions of...

Diroximel Fumarate (Vumerity) Cleared for MS in Europe

Nov 17th, 2021 - The European Commission (EC) has approved diroximel fumarate (Vumerity, Biogen Inc) for treatment of adults with relapsing-remitting multiple sclerosis (MS). The approval follows a thumbs-up from the Committee for Medicinal Products for Human Use ...

Looking Beyond the Typical Measures of MS Diagnosis

Nov 10th, 2021 - This transcript has been edited for clarity. Hi. I'm Stephen Krieger from Mount Sinai in New York, here with an update from the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) congress, which was not held in Vienna as...

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Patient Education  57 results see all →