ALLMedicine™ Parkinson Disease Center

Nov 29th, 2021 - In addition to motor dysfunction, cognitive impairments have been reported to occur in patients with early-stage Parkinson's disease (PD). In this study, we examined a PD mouse model induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). ...

Nov 26th, 2021 - This study evaluated the amount of phonatory activity of Persons with Parkinson disease (PwPD) compared to adults without Parkinson's disease measured over 3 days. The relationship between the amount of phonatory activity and Voice Handicap Index ...

Nov 26th, 2021 - The International Parkinson and Movement Disorder Society (MDS) has published research criteria for prodromal Parkinson's disease (pPD), which includes cognitive impairment as a prodromal marker. However, the clinical features of mild cognitive im...

Nov 24th, 2021 - Parkinson disease remains a debilitating neurodegenerative disorder, despite the discovery of multiple causative genes that account for familial forms. Prominent among these are PRKN/Parkin and PINK1, whose protein products participate in mitochon...

Nov 23rd, 2021 - Parkinson disease (PD) is a progressive neurological disease resulting in motor impairments, postural instability, and gait alterations which may result in self-care limitations and loss of mobility reducing quality of life. This study's purpose w...

Nov 23rd, 2021 - Dementia with Lewy bodies (DLB) is part of Lewy body dementia, the 2nd-most-common degenerative dementia in the U.S. It is also one of the Alzheimer's disease-related dementias (ADRDs). Evidence-based models of end-of-life care for ADRDs are insuf...

Nov 19th, 2021 - Each participant would complete four test days and each test day is separated by 7-10 days. At each test day the participants would complete a graded maximal exercise test (VO2max-test), a chair rise (Linear encoder) as well as measuring of basic ...

Nov 2nd, 2021 - Patients with subthalamic nucleus have to go through a lot of examinations and tests, before and after surgery which is difficult, sometimes painful, for the patient. The investigators used to chose the best plot of the leads for stimulation by a ...

Oct 1st, 2021 - Introduction Parkinson disease (PD) is a neurodegenerative disease of the brain, leads to degeneration and causing the motor and non-motor symptoms. PD is characterized by dopaminergic neurotransmitter deficiency. It is a progressive neurological ...

Sep 30th, 2021 - Dementia is a progressive decline in cognition that impairs a person's ability to perform activities of daily living. Alzheimer's disease is the most common form of dementia, the most common neurodegenerative disease in older adults, and the 6th l...

Sep 21st, 2021 - Before getting to work on developing guidelines for genetic testing in Parkinson’s disease, a task force of the Movement Disorders Society surveyed members worldwide to identify concerns they have about using genetic testing in practice. In result.

Sep 19th, 2021 - A majority of patients with Parkinson disease (PD) experiencing "off" episodes  successfully tolerated titration to an effective and tolerable dose of sublingual apomorphine film (SL-apo; Kynmobi, Sunovion Pharmaceuticals) without the use of antie...

Sep 14th, 2021 - The outcome of deep brain stimulation (DBS) surgery for Parkinson disease (PD) is comparable when performed under general or local anesthesia, results of a new randomized trial show. Investigators note that postoperative confusion frequently occur...

May 19th, 2021 - A 75-year-old man with Parkinson’s disease has had three falls over the past 4 weeks. He has been compliant with his Parkinson’s treatment.

Apr 29th, 2021 - In this supplement to Neurology Reviews, the authors provide a general overview of the OFF state, including unexpected OFF; cover the importance of distinguishing unexpected OFF from other OFF states before deciding on treatment options; explain h.