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About 57,088 results

ALLMedicine™ Seizures Center

Research & Reviews  18,123 results

Down-regulation of the brain-specific cell-adhesion molecule contactin-3 in tuberous sc...
https://doi.org/10.1186/s11689-022-09416-2
Journal of Neurodevelopmental Disorders; Korotkov A, Luinenburg MJ et. al.

Jan 16th, 2022 - The genetic disorder tuberous sclerosis complex (TSC) is frequently accompanied by the development of neuropsychiatric disorders, including autism spectrum disorder and intellectual disability, with varying degrees of impairment. These co-morbidit...

Cerebrospinal Fluid Ion Analysis in Neonatal Seizures.
https://doi.org/10.1016/j.pediatrneurol.2021.11.013
Pediatric Neurology; Casas-Alba D, Oliva C et. al.

Jan 16th, 2022 - There is a gap of knowledge regarding cerebrospinal fluid (CSF) ion concentrations in normal and pathological states, particularly during the neonatal period. We aim to compare CSF ion concentrations in newborns with different causes of neonatal-o...

Pediatric GAD-65 Autoimmune Encephalitis: Assessing Clinical Characteristics and Respon...
https://doi.org/10.1016/j.pediatrneurol.2021.12.007
Pediatric Neurology; Harmon A, Stingl C et. al.

Jan 16th, 2022 - Glutamic acid decarboxylase (GAD) encephalitis is a neuroinflammatory disease characterized by a broad range of symptoms including cognitive deficits, behavioral changes, and seizures. Children with this disorder have heterogeneous presentations, ...

CASPR2-IgG-associated autoimmune seizures.
https://doi.org/10.1111/epi.17164
Epilepsia Garrido Sanabria ER, Zahid A et. al.

Jan 16th, 2022 - This study was undertaken to report clinical presentations and outcomes of CASPR2-IgG-associated seizures. Mayo Clinic Neuroimmunology database was queried to identify CASPR2-IgG-seropositive (CASPR2-IgG+) patients evaluated at our institution (20...

Improved access to rapid electroencephalography at a community hospital reduces inter-h...
https://doi.org/10.1684/epd.2021.1410
Epileptic Disorders : International Epilepsy Journal With... Madill ES, Gururangan K et. al.

Jan 16th, 2022 - Patients with suspected non-convulsive seizures are optimally evaluated with EEG. However, limited EEG infrastructure at community hospitals often necessitates transfer for long-term EEG monitoring (LTM). Novel point-of-care EEG systems could expe...

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Guidelines  20 results

ACR Appropriateness Criteria® Seizures-Child.
https://doi.org/10.1016/j.jacr.2021.02.020
Journal of the American College of Radiology : JACR; , Trofimova A et. al.

May 8th, 2021 - In children, seizures represent an extremely heterogeneous group of medical conditions ranging from benign cases, such as a simple febrile seizure, to life-threatening situations, such as status epilepticus. Underlying causes of seizures also repr...

ACR Appropriateness Criteria® Cerebrovascular Disease-Child.
https://doi.org/10.1016/j.jacr.2020.01.036
Journal of the American College of Radiology : JACR; , Robertson RL et. al.

May 7th, 2020 - Stroke is an uncommon but an important and under-recognized cause of morbidity and mortality in children. Strokes may be due to either brain ischemia or intracranial hemorrhage. Common symptoms of pediatric acute stroke include headache, vomiting,...

ACR Appropriateness Criteria® Seizures and Epilepsy.
https://doi.org/10.1016/j.jacr.2020.01.037
Journal of the American College of Radiology : JACR; , Lee RK et. al.

May 7th, 2020 - Seizures and epilepsy are a set of conditions that can be challenging to diagnose, treat, and manage. This document summarizes recommendations for imaging in different clinical scenarios for a patient presenting with seizures and epilepsy. MRI of ...

Practice guideline update summary: Efficacy and tolerability of the new antiepileptic d...
https://doi.org/10.1212/WNL.0000000000005755
Neurology Kanner AM, Ashman E et. al.

Jun 15th, 2018 - To update the 2004 American Academy of Neurology (AAN) guideline for treating new-onset focal or generalized epilepsy with second- and third-generation antiepileptic drugs (AEDs). The 2004 AAN criteria were used to systematically review literature...

SEOM clinical guidelines for diagnosis and treatment of glioblastoma (2017).
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785619
Clinical & Translational Oncology : Official Publication ... Martínez-Garcia M, Álvarez-Linera J et. al.

Nov 1st, 2017 - Glioblastoma (GB) is the most common brain malignancy and accounts for over 50% of all high-grade gliomas. Radiotherapy (RT) with concomitant and adjuvant temozolomide (TMZ) chemotherapy is the current standard of care for patients with newly diag...

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Drugs  2,046 results see all →

Clinicaltrials.gov  507 results

A Study to Test the Safety/ Efficacy of Brivaracetam (BRV) Used as Adjunctive Treatment in Subjects >=16 Years of Age With Partial Seizures With or Without Secondary Generalization
https://clinicaltrials.gov/ct2/show/NCT03250377

Jan 10th, 2022 - The purpose of the study is to evaluate the long-term safety and tolerability of Brivaracetam (BRV) in focal epilepsy subjects with partial seizures and to evaluate the maintenance of efficacy of BRV over time.

A Natural History Study of Aspartylglucosaminuria
https://clinicaltrials.gov/ct2/show/NCT03853876

Jan 10th, 2022 - Lysosomal storage disorders (LSDs) are a group of inherited metabolic diseases caused by a genetic mutation resulting in deficiency or absence of a critical enzyme, leading to the accumulation of toxic deposits in cells across multiple organ syste...

A Natural History Study of Late Infantile Variant CLN5 And CLN7 Disease
https://clinicaltrials.gov/ct2/show/NCT03822650

Jan 10th, 2022 - Neuronal Ceroid Lipofuscinosis (NCL) are comprised of a group of fatal neurodegenerative diseases caused by mutations in an enzyme or protein which results in the accumulation of toxic deposits in the eye, brain, skin, muscle and other cells. CLN5...

A Study to Test the Efficacy and Safety of Staccato Alprazolam in Study Participants 12 Years of Age and Older With Stereotypical Prolonged Seizures
https://clinicaltrials.gov/ct2/show/NCT05077904

Jan 10th, 2022 - The purpose of the study is to assess the success of a single administration of Staccato alprazolam compared with placebo both in rapidly terminating a seizure episode within 90 seconds and with no recurrence of seizure(s) up to 2 hours after inve...

A Study to Investigate JNJ-40411813 in Combination With Levetiracetam in Epilepsy
https://clinicaltrials.gov/ct2/show/NCT04836559

Jan 6th, 2022 - The purpose of this study is to evaluate the efficacy of up to 3 dose levels of adjunctive JNJ-40411813 compared to placebo based on the time to baseline monthly seizure count in participants with focal onset seizures who are receiving levetiracet...

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News  1,945 results

Individualize the duration of postpartum magnesium treatment for patients with preeclampsia to best balance the benefits and harms of treatment
https://www.mdedge.com/obgyn/article/250581/obstetrics/individualize-duration-postpartum-magnesium-treatment-patients
Robert L. Barbieri, MD

Jan 10th, 2022 - Preeclampsia complicates 3% to 8% of pregnancies. 1-3 The incidence of preeclampsia is influenced by the clinical characteristics of the pregnant population, including the prevalence of overweight, obesity, chronic hypertension, diabetes, nullipari.

Whole-plant Cannabis Linked to Large Reduction in Seizures
https://www.medscape.com/viewarticle/965756

Dec 29th, 2021 - Whole-plant cannabis is linked to a significant reduction in seizures in children with severe treatment-resistant epilepsy, early research suggests. In a small case series, children with severe treatment-resistant epilepsy treated with a range of ...

Epilepsy in older adults: Misdiagnosis and case complexity are common
https://www.mdedge.com/neurology/article/250198/epilepsy-seizures/epilepsy-older-adults-misdiagnosis-and-case-complexity
Randy Dotinga

Dec 22nd, 2021 - Many older adults with epilepsy are misdiagnosed even though the highest incidence of the disease is in people over 75, a neurologist told an audience at the annual meeting of the American Epilepsy Society. She urged colleagues to focus on possibl.

Should Electrographic Seizures Be Treated in Neonates?
https://www.medpagetoday.com/neurology/seizures/96254

Dec 17th, 2021 - Treating both clinical and electrographic seizures in newborns did not lead to better survival or neurodevelopmental outcomes at 2 years compared with treating only clinically detected seizures, a randomized trial showed. Odds of death or severe d...

When the benchwarmer is a slugger
https://www.mdedge.com/neurology/article/249903/business-medicine/when-benchwarmer-slugger
Allan M. Block, MD

Dec 14th, 2021 - I still, on occasion, use Felbatol (felbamate). Dr.

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Patient Education  194 results see all →