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About 33,985 results

ALLMedicine™ Hypotension Center

Research & Reviews  9,909 results

Feasibility, reliability and safety of self-assessed orthostatic blood pressure at home.
https://doi.org/10.1093/ageing/afac153
Age and Ageing; Gibbon JR, Parry SW et. al.

Jul 2nd, 2022 - A postural blood pressure assessment is required to diagnose Orthostatic Hypotension. With increasing remote consultations, alternative methods of performing postural blood pressure assessment are required. Determine whether postural blood pressur...

Orthostatic blood pressure recovery in older males using alpha-blockers for lower urina...
https://doi.org/10.1111/jcpt.13726
Journal of Clinical Pharmacy and Therapeutics; Spies PE, Beune TNN et. al.

Jul 2nd, 2022 - Alpha-blockers have been associated with orthostatic hypotension (OH). We aimed to assess the prevalence of OH measured with beat-to-beat blood pressure monitoring in older male outpatients who used alpha-blockers for lower urinary tract symptoms ...

Safety outcomes of SGLT2i in the heart failure trials: A systematic review and Meta-ana...
https://doi.org/10.1016/j.ijcard.2022.06.059
International Journal of Cardiology; Younes AM, Salem M et. al.

Jul 2nd, 2022 - Sodium-glucose co-transporter inhibitors (SGLT2i) are emerging as a new treatment for heart failure (HF) after demonstrating favorable clinical outcomes in several randomized controlled trials (RCTs). In this meta-analysis, we assessed the safety ...

Regulation of blood vessels by ATP in the ventral medullary surface in a rat model of P...
https://doi.org/10.1016/j.brainresbull.2022.06.011
Brain Research Bulletin; Oliveira LM, Fernandes-Junior SA et. al.

Jul 2nd, 2022 - Parkinson's disease (PD) patients often experience impairment of autonomic and respiratory functions. These include conditions such as orthostatic hypotension and sleep apnea, which are highly correlated with dysfunctional central chemoreception. ...

Population pharmacokinetic modeling of CSF to blood clearance: prospective tracer study...
https://doi.org/10.1186/s12987-022-00352-w 10.7326/0003-4819-139-2-200307150-00013 10.1126/scitranslmed.3003748 10.1038/nature14432 10.1126/science.abb8739 10.1172/JCI90603 10.1038/s41467-020-18113-4 10.1038/s41586-019-1912-x 10.1038/s41422-020-0287-8 10.1038/s41598-019-51373-9 10.1177/0271678X18822921 10.1038/s41467-020-16851-z 10.1038/s41586-021-03489-0 10.1038/s41591-020-01198-1 10.1007/s00702-012-0772-4 10.1038/nrneurol.2010.4 10.1016/j.apsb.2020.01.015 10.1007/s00415-018-9124-0 10.1186/s13046-019-1180-5 10.1186/s40478-019-0664-z 10.3791/60274 10.1172/jci.insight.121537 10.1093/brain/awx191 10.1038/s41467-019-14195-x 10.1093/brain/awab388 10.1038/s41598-018-25666-4 10.1172/jci.insight.147063 10.1186/s13024-019-0312-x 10.1227/01.NEU.0000363408.69856.B8 10.1016/j.wneu.2015.09.067 10.2176/nmc.52.775 10.1097/FTD.0b013e31825c4ba6 10.1097/RLI.0b013e3181bfe2d2 10.1097/RLI.0000000000000204 10.2967/jnumed.116.187211 10.1186/s12987-022-00318-y 10.2967/jnumed.117.190611 10.1177/0271678X18760974 10.1093/braincomms/fcaa187 10.1038/s41598-019-56847-4 10.1186/1743-8454-7-9 10.1038/s41467-019-12568-w 10.1016/S1286-0115(05)83235-7 10.1038/s41467-017-01484-6 10.1186/2045-8118-11-10 10.1093/jmicro/dfaa038 10.1007/s00234-020-02519-4 10.1002/ana.25670 10.1186/s40035-019-0147-y 10.1111/bpa.12656 10.1038/s41586-018-0368-8 10.1016/j.neuron.2014.12.032 10.1038/s41586-020-2247-3 10.1093/jnen/nlz063 10.1016/j.brainres.2019.146547 10.1097/00004424-199407000-00008 10.1227/NEU.0b013e3182134399 10.1111/j.1552-6569.2008.00270.x 10.1002/ana.24270 10.1186/s13195-020-00688-1 10.1186/2045-8118-8-7 10.1172/jci.insight.129240 10.1016/S0140-6736(16)31408-8 10.1155/2019/4047617 10.1016/j.emc.2013.09.002 10.1172/JCI99081 10.1126/scitranslmed.aap8677 10.1080/14712598.2018.1416089 10.3174/ajnr.A6136 10.1148/radiol.2020191373
Fluids and Barriers of the CNS; Hovd MH, Mariussen E et. al.

Jul 2nd, 2022 - Quantitative measurements of cerebrospinal fluid to blood clearance has previously not been established for neurological diseases. Possibly, variability in cerebrospinal fluid clearance may affect the underlying disease process and may possibly be...

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Guidelines  11 results

Management of Pyrexia Associated with the Combination of Dabrafenib and Trametinib: Can...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8482100
Current Oncology (Toronto, Ont.); Thawer A, Miller WH et. al.

Oct 1st, 2021 - The combination of dabrafenib and trametinib is a well-established treatment for BRAF-mutated melanoma. However, the effectiveness of this approach may be hindered by the development of treatment-related pyrexia syndrome, which occurs in at least ...

My Treatment Approach to Multiple System Atrophy.
https://doi.org/10.1016/j.mayocp.2020.10.005
Mayo Clinic Proceedings; Coon EA, Ahlskog JE

Mar 7th, 2021 - Multiple system atrophy (MSA) is a neurodegenerative disorder primarily characterized by autonomic failure plus parkinsonism or cerebellar ataxia. The diagnosis may be challenging and is usually made at a tertiary care center. The long-term manage...

Canadian Cardiovascular Society Position Statement on Postural Orthostatic Tachycardia ...
https://doi.org/10.1016/j.cjca.2019.12.024
The Canadian Journal of Cardiology; Raj SR, Guzman JC et. al.

Mar 9th, 2020 - The current definition of postural orthostatic tachycardia syndrome (POTS) dates back to a small case series of patients with a subacute illness who presented with excessive orthostatic tachycardia and orthostatic intolerance, in the absence of an...

The international anorectal physiology working group (IAPWG) recommendations: Standardi...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923590
Neurogastroenterology and Motility : the Official Journal... Carrington EV, Heinrich H et. al.

Aug 14th, 2019 - This manuscript summarizes consensus reached by the International Anorectal Physiology Working Group (IAPWG) for the performance, terminology used, and interpretation of anorectal function testing including anorectal manometry (focused on high-res...

Choosing Wisely in pediatric anesthesia: An interpretation from the German Scientific W...
https://doi.org/10.1111/pan.13383
Paediatric Anaesthesia; Becke K, Eich C et. al.

Jun 1st, 2018 - Inspired by the Choosing Wisely initiative, a group of pediatric anesthesiologists representing the German Working Group on Paediatric Anaesthesia (WAKKA) coined and agreed upon 10 concise positive ("dos") or negative ("don'ts") evidence-based rec...

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Drugs  601 results see all →

Clinicaltrials.gov  1,930 results

Clinical Laboratory Evaluation of Chronic Autonomic Failure
https://clinicaltrials.gov/ct2/show/NCT03648905

Jul 1st, 2022 - Objective: In dysautonomias, altered function of one or more components of the autonomic nervous system adversely affect health. A subset of dysautonomias consists of chronic autonomic failure (CAF) syndromes. A key sign of CAF is orthostatic hypo...

T Cells Expressing a Novel Fully-Human Anti-BCMA CAR for Treating Multiple Myeloma
https://clinicaltrials.gov/ct2/show/NCT03602612

Jul 1st, 2022 - Background: Multiple myeloma (MM) is a malignancy of plasma cells. MM is nearly always incurable. T cells can be genetically modified to express chimeric antigen receptors (CARs) that specifically target malignancy-associated antigens. Autologous ...

Midodrine as Novel Treatment of Post-Cardiopulmonary Bypass Vasoplegic Syndrome
https://clinicaltrials.gov/ct2/show/NCT04668859

Jul 1st, 2022 - Vasoplegic syndrome (VS) is a common and serious complication of cardiopulmonary bypass (CPB) procedures associated with a significant increase in morbidity and mortality. VS is defined as significant hypotension, high or normal cardiac outputs, l...

Studies in the Pathogenesis of Systemic Capillary Leak Syndrome
https://clinicaltrials.gov/ct2/show/NCT00936325

Jul 1st, 2022 - The systemic capillary leak syndrome (SCLS, Clarkson syndrome) is an exceedingly rare disorder of unknown cause characterized by chronic edema or acute transient, severe episodes of hypotension, hypovolemia, and oliguria. Severe edema results from...

Nol-Index Guided Remifentanil Analgesia Versus Standard Analgesia During Moderate-to-High Risk Cardiovascular Surgery
https://clinicaltrials.gov/ct2/show/NCT04137991

Jul 1st, 2022 - Justification: Moderate-to-high risk cardiovascular surgery is associated with perioperative morbidity and mortality. These patients undergo general anesthesia and often require tight blood pressure control (e.g., using norepinephrine titration) t...

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News  1,132 results

Should you treat asymptomatic bacteriuria in an older adult with altered mental status?
https://www.mdedge.com/familymedicine/article/255368/geriatrics/should-you-treat-asymptomatic-bacteriuria-older-adult
MDedge Family Medicine; L. Amanda Perry, MD, A. Justine Landi, MD

Jun 13th, 2022 - THE CASE A 78-year-old woman with a past medical history of hypertension, hyperlipidemia, osteoarthritis, and osteopenia was brought to the emergency department (ED) by her daughter. The woman had fallen 2 days earlier and had been experiencing a.

Myosin Activator May Benefit Data-Deprived Patients With Heart Failure and Low Blood Pressure
https://www.medscape.com/viewarticle/974960

Jun 2nd, 2022 - The evidence base supporting many drugs used in heart failure (HF) can be pretty thin for some types of patients, in particular those who have typically been excluded from major trials but aren’t all that rare in practice. But a post hoc analysis ...

Fall Injury Among Community-Dwelling Older Adults: Effect of a Multifactorial Intervention and a Home Hazard Removal Program
https://www.mdedge.com/jcomjournal/article/255039/geriatrics/fall-injury-among-community-dwelling-older-adults-effect
William W. Hung, MD, MPH

May 27th, 2022 - Study 1 Overview (Bhasin et al) Objective: To examine the effect of a multifactorial intervention for fall prevention on fall injury in community-dwelling older adults. Design: This was a pragmatic, cluster randomized trial conducted in 86 primary.

SOT101 Plus Pembrolizumab Elicits Encouraging Efficacy in Advanced Solid Tumors
https://www.onclive.com/view/sot101-plus-pembrolizumab-elicits-encouraging-efficacy-in-advanced-solid-tumors

May 2nd, 2022 - The addition of SOT101, an interleukin (IL)-2/IL-15 Rβγ superagonist, to Pembrolizumab (Keytruda) generated a clinical benefit and encouraging safety data in patients with advanced solid tumors, according to data presented at the 2022 AACR Annual ...

FDA Approves Axicabtagene Ciloleucel for Second-Line LBCL
https://www.onclive.com/view/fda-approves-axicabtagene-ciloleucel-for-second-line-lbcl

Apr 28th, 2022 - The FDA has approved axicabtagene ciloleucel (axi-cel; Yescarta) for the treatment of adult patients with large B-cell lymphoma that is refractory to first-line chemoimmunotherapy or relapses within 12 months of first-line chemoimmunotherapy.1 Th...

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Patient Education  11 results see all →