ALLMedicine™ Chronic Cough Center

Dec 1st, 2021 - Most patients with cystic fibrosis (CF) develop multisystemic clinical manifestations, the minority having mild or atypical symptoms. We describe an adolescent with chronic cough and purulent rhinorrhoea since the first year of life, with diagnose...

Nov 26th, 2021 - Gefapixant (MK-7264, AF-219), a first-in-class P2X3 antagonist, is being developed as oral treatment for refractory or unexplained chronic cough. Based on in vitro data, gefapixant exerts inhibitory activity on the organic anion transporter (OAT) ...

Nov 23rd, 2021 - Background The diagnosis of gastro-esophageal reflux disease (GERD) is difficult when patients present with extra-esophageal symptoms such as chronic cough, frequent throat clearing, globus sensation, sore throat, and hoarseness, as opposed to the...

Nov 22nd, 2021 - Bronchiectasis, defined by an increase in bronchial caliber and thickening of the bronchial wall, is associated with recurrent respiratory infections, chronic cough and bronchorrhea, and a frequent progression to chronic respiratory failure. Inves...

Nov 22nd, 2021 - Laryngopharyngeal reflux (LPR) causes chronic cough, throat clearing, hoarseness, and dysphagia and if left untreated can promote the development of laryngeal cancer. More than 20% of the United Stated population suffer from LPR, yet there is no e...

Nov 20th, 2021 - Chronic cough is defined by a duration lasting at least 8 weeks. The most common causes of chronic cough include smoking-related lung disease, upper airway cough syndrome, asthma, gastroesophageal reflux disease, and nonasthmatic eosinophilic bron...

Mar 18th, 2020 - Cough is one of the most common presenting symptoms to general practitioners. The objective of this article is to collate the pediatric components of the CHEST chronic cough guidelines that have recently updated the 2006 guidelines to assist gener...

Feb 28th, 2020 - Chronic cough due to chronic bronchitis (CB) causes significant impairment in quality of life, and effective treatment strategies are needed. We conducted a systematic review on the management of chronic cough due to CB to update the recommendatio...

Feb 25th, 2020 - Evidence for the diagnosis and management of cough due to acute bronchitis in immunocompetent adult outpatients was reviewed as an update to the 2006 "Chronic Cough Due to Acute Bronchitis: American College of Chest Physicians (ACCP) Evidence-Base...

Jan 24th, 2020 - Asthma and non-asthmatic eosinophilic bronchitis (NAEB) are among the commonest causes of chronic cough in adults. We sought to determine the role of non-invasive measurements of airway inflammation, including induced sputum and fractional exhaled...

Nov 23rd, 2021 - Background The diagnosis of gastro-esophageal reflux disease (GERD) is difficult when patients present with extra-esophageal symptoms such as chronic cough, frequent throat clearing, globus sensation, sore throat, and hoarseness, as opposed to the...

Nov 22nd, 2021 - Bronchiectasis, defined by an increase in bronchial caliber and thickening of the bronchial wall, is associated with recurrent respiratory infections, chronic cough and bronchorrhea, and a frequent progression to chronic respiratory failure. Inves...

Nov 22nd, 2021 - Laryngopharyngeal reflux (LPR) causes chronic cough, throat clearing, hoarseness, and dysphagia and if left untreated can promote the development of laryngeal cancer. More than 20% of the United Stated population suffer from LPR, yet there is no e...

Nov 16th, 2021 - This is a randomized, double-blind, placebo-controlled, parallel-arm, dose escalation study of Duloxetine & Amitriptyline in subjects with interstitial lung disease-related chronic cough. Subjects will be screened during a period of up to 2 week a...

Nov 5th, 2021 - This is a randomized, double-blind, placebo-controlled, parallel-arm, dose escalation study of Duloxetine & Amitriptyline in subjects with refractory chronic cough. Subjects will be screened during a period of up to 2 week and will undergo screeni...

Sep 8th, 2021 - (Reuters) - A legal battle is brewing over remote work between administrators at U.S. colleges committed to in-person classes and some faculty with disabilities. Experts warn it is a precursor of what awaits employers that order staff back to the ...

Feb 12th, 2021 - Gastroesophageal reflux disease (GERD) affects as many as 28% of North American residents. Marked by an excessive backup of gastric contents into the esophagus leading to troublesome symptoms and/or complications, it can result from dysfunction of...

Feb 4th, 2021 - Idiopathic pulmonary fibrosis (IPF) is the most common form of chronic, progressive fibrosing interstitial pneumonia of unknown origin. The histopathology and radiological findings of IPF are the same as those of usual interstitial pneumonia (UIP)...

Jan 29th, 2021 - THE CASE A 60-year-old man with a past medical history of gastroesophageal reflux disease (GERD) and dyslipidemia presented to his family physician for evaluation of chronic cough. Five years prior, the patient had developed a high fever and respi.

Dec 22nd, 2020 - This transcript has been edited for clarity. Matthew F. Watto, MD: Hey guys, we're back. Believe it or not, we are three board-certified internal medicine physicians. I'm Dr Matthew Frank Watto. Stuart K. Brigham, MD: I'm Stuart Brigham. Paul N. W...