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About 8,235 results

ALLMedicine™ Purpura Center

Research & Reviews  2,606 results

Reactivation of IgA vasculitis following COVID-19 vaccination.
https://doi.org/10.1136/bcr-2021-247188
BMJ Case Reports; Maye JA, Chong HP et. al.

Dec 2nd, 2021 - A 23-year-old man presented to the acute assessment unit with acute-onset haematuria within 24 hours of receiving his second dose of the Pfizer-BioNTech COVID-19 vaccine. He had been diagnosed with IgA vasculitis 8 months previously. IgA vasculiti...

Comparison of clinical, pathological and long-term renal outcomes of children with Heno...
https://doi.org/10.1007/s11255-021-03063-7 10.1007/s00296-016-3425-3 10.1007/s00467-017-3597-4 10.1007/s11695-017-2940-y
International Urology and Nephrology; Torun Bayram M, Heybeli C et. al.

Dec 1st, 2021 - To compare clinical, pathological, and long-term renal outcomes of children with Henoch-Schonlein purpura nephritis (HSPN) and IgA nephropathy (IgAN). The medical records of patients diagnosed as HSPN and IgAN during childhood were evaluated retro...

Morbidities and Mortality in Patients with Hereditary Thrombotic Thrombocytopenic Purpura.
https://doi.org/10.1182/bloodadvances.2021005760
Blood Advances; Borogovac A, Reese JA et. al.

Nov 23rd, 2021 - Hereditary thrombotic thrombocytopenic purpura (hTTP) is a rare disorder caused by severe ADAMTS13 deficiency. Major morbidities and death at a young age are common. Although ADAMTS13 replacement can prevent morbidities and death, current regimens...

Vaccines for measles, mumps, rubella, and varicella in children.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8607336
The Cochrane Database of Systematic Reviews; Di Pietrantonj C, Rivetti A et. al.

Nov 23rd, 2021 - Measles, mumps, rubella, and varicella (chickenpox) are serious diseases that can lead to serious complications, disability, and death. However, public debate over the safety of the trivalent MMR vaccine and the resultant drop in vaccination cover...

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Guidelines  4 results

Oropharyngeal psychogenic purpura.
https://doi.org/10.1111/bjh.17021
British Journal of Haematology; Allar BG, Michaelsen K et. al.

Aug 6th, 2020 - Oropharyngeal psychogenic purpura.|2020|Allar BG,Michaelsen K,Gupta A,Bose S,|metabolism,pathology,metabolism,pathology,metabolism,pathology,metabolism,pathology,metabolism,pathology,

European consensus-based recommendations for diagnosis and treatment of immunoglobulin ...
https://doi.org/10.1093/rheumatology/kez041
Rheumatology (Oxford, England); Ozen S, Marks SD et. al.

Mar 18th, 2019 - IgA vasculitis (IgAV, formerly known as Henoch-Schönlein purpura) is the most common cause of systemic vasculitis in childhood. To date, there are no internationally agreed, evidence-based guidelines concerning the appropriate diagnosis and treatm...

ACG Clinical Guideline: Treatment of Helicobacter pylori Infection.
https://doi.org/10.1038/ajg.2016.563
The American Journal of Gastroenterology; Chey WD, Leontiadis GI et. al.

Jan 11th, 2017 - Helicobacter pylori (H. pylori) infection is a common worldwide infection that is an important cause of peptic ulcer disease and gastric cancer. H. pylori may also have a role in uninvestigated and functional dyspepsia, ulcer risk in patients taki...

Guidelines for the diagnosis and management of disseminated intravascular coagulation. ...
https://doi.org/10.1111/j.1365-2141.2009.07600.x
British Journal of Haematology; Levi M, Toh CH et. al.

Feb 19th, 2009 - The diagnosis of disseminated intravascular coagulation (DIC) should encompass both clinical and laboratory information. The International Society for Thrombosis and Haemostasis (ISTH) DIC scoring system provides objective measurement of DIC. Wher...

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Drugs  329 results see all →

Clinicaltrials.gov  82 results

Magnesium Sulfate in Thrombotic Thrombocytopenic Purpura in Intensive Care
https://clinicaltrials.gov/ct2/show/NCT03237819

Oct 29th, 2021 - Thrombotic Thrombocytopenic Purpura (TTP) is a potentially life-threatening thrombotic microangiopathy caused by a severe deficiency of ADAMTS13 (a disintegrin and metalloproteinase with a thrombospondin type 1 motif member 13). Decreased ADAMTS13...

The Therapeutic Value and Mechanism of Recombinant Human Interleukin-2 in Children With Henoch-schönlein Purpura
https://clinicaltrials.gov/ct2/show/NCT04387942

Oct 14th, 2021 - The investigators designed a single center, open-label, prospective study that routinely administered low-dose IL-2 therapy to monitor the improvement of clinical and laboratory parameters to explore its efficacy and to observe changes in immune c...

Efficacy of Colchicine to Prevent Skin Relapses in Adult's IgA Vasculitis
https://clinicaltrials.gov/ct2/show/NCT04008316

Oct 4th, 2021 - Immunoglobulin A vasculitis (IgA-V), formerly called Henoch-Schönlein purpura, is an immune vasculitis. Relapses are frequent (30%) and most of the time cutaneous (90%). Cutaneous involvement in adults is more severe (haemorrhagic blister or necro...

Improvement of Immunologic and Molecular Techniques for the Diagnosis and Follow-up of Patients With Thrombotic Thrombocytopenic Purpura
https://clinicaltrials.gov/ct2/show/NCT05046717

Sep 16th, 2021 - The lack of ADAMTS13 is the only biological marker that is specific for aTTP diagnosis8 and the assessment of ADAMTS13 is of clinical importance because it is essential for the rapid differential diagnosis between aTTP and other TMA. Furthermore, ...

A Trial of Caplacizumab in Japanese Patients With Acquired Thrombotic Thrombocytopenic Purpura (aTTP)
https://clinicaltrials.gov/ct2/show/NCT04074187

Sep 9th, 2021 - Study duration per participant is approximately 2 months up to approximately 6 months in case of treatment extension and recurrence during the study drug treatment period.

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News  263 results

Large Leg Ulcers After Swimming in the Ocean
https://www.mdedge.com/dermatology/article/249007/infectious-diseases/large-leg-ulcers-after-swimming-ocean
Paul Macklis, MD, MS, Cory Pettit, MD et. al.

Nov 22nd, 2021 - The Diagnosis: Vibrio vulnificus Infection At the initial presentation, the differential diagnosis included infectious processes such as bacterial or angioinvasive fungal infections or an inflammatory process such as pyoderma gangrenosum. Blood cu.

Spreading Newfound Treatment Strategies in Hematologic Malignancies in Seattle
https://www.onclive.com/view/spreading-newfound-treatment-strategies-in-hematologic-malignancies-in-seattle

Oct 6th, 2021 - We recently traveled to Seattle, California for an OncLive® State of the Science Summit™ on Hematologic Malignancies. At the meeting, faculty from Seattle Cancer Care Alliance provided insight on current and evolving standards of care in leukemia,...

COVID-19: 2 More Cases of Mucosal Skin Ulcers Reported in Male Teens
https://www.medscape.com/viewarticle/959283

Sep 22nd, 2021 - Irish dermatologists are reporting two more cases of a rare skin ulcer known as reactive infectious mucocutaneous eruption (RIME) in teenage males who were infected with COVID-19. A similar case in an adolescent, also with ulcers affecting the mou...

ITP after COVID-19 Vaccination at the Salisbury VA Healthcare System: Case Studies
https://www.mdedge.com/fedprac/avaho/article/245953/vaccines/itp-after-covid-19-vaccination-salisbury-va-healthcare-system
Elizabeth Agnew, DO ([email protected]), Hope N. Schenk, PharmD, BCOP

Sep 10th, 2021 - Background An association between vaccines and the rare development of immune thrombocytopenic purpura (ITP) has been reported in the literature. More recently, there have been a few case reports published describing patients developing ITP shortl.

Bullous Retiform Purpura on the Ears and Legs
https://www.mdedge.com/dermatology/article/244159/dermatopathology/bullous-retiform-purpura-ears-and-legs
Shane M. Swink, DO, MS, Naeha Gupta, DO et. al.

Aug 11th, 2021 - The Diagnosis: Levamisole-Induced Vasculopathy Biopsy of one of the bullous retiform purpura on the leg (Figure 1) revealed a combined leukocytoclastic vasculitis and thrombotic vasculopathy (quiz images). Periodic acid-Schiff and Gram stains, wit.

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Patient Education  10 results see all →