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About 4,521 results

ALLMedicine™ Apolipoprotein B Center

Research & Reviews  2,183 results

Per-Particle Triglyceride-Rich Lipoproteins Imply Higher Myocardial Infarction Risk Tha...
https://doi.org/10.1161/ATVBAHA.120.315639
Arteriosclerosis, Thrombosis, and Vascular Biology; Johansen MØ, Vedel-Krogh S et. al.

Apr 8th, 2021 - ApoB (Apolipoprotein B)-containing triglyceride-rich lipoproteins and LDL (low-density lipoproteins) are each causal for myocardial infarction and atherosclerotic cardiovascular disease; however, the relative importance is unknown. We tested the h...

Genetics of hypertriglyceridemia and atherosclerosis.
https://doi.org/10.1097/HCO.0000000000000839
Current Opinion in Cardiology; Gill PK, Dron JS et. al.

Apr 5th, 2021 - The relationship between elevated triglyceride levels (i.e. hypertriglyceridemia) and risk of atherosclerotic cardiovascular disease (ASCVD) has been investigated for decades. Recent genetic studies have sought to resolve the decades-old question ...

LDL/apo B ratio predict coronary heart disease in Type 2 diabetes independent of ASCVD ...
https://doi.org/10.1016/j.numecd.2021.01.013
Nutrition, Metabolism, and Cardiovascular Diseases : NMCD; Rabizadeh S, Rajab A et. al.

Apr 3rd, 2021 - Coronary heart disease (CHD) is a major mortality risk factor in patients with diabetes. LDL cholesterol (LDL-C) is a major risk factor for the development of atherosclerosis. There is one apolipoprotein B (ApoB) molecule in each LDL particle. We ...

Baseline cardiometabolic profiles and SARS-CoV-2 infection in the UK Biobank.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016301
PloS One; Scalsky RJ, Chen YJ et. al.

Apr 1st, 2021 - SARS-CoV-2 is a rapidly spreading coronavirus responsible for the Covid-19 pandemic, which is characterized by severe respiratory infection. Many factors have been identified as risk factors for SARS-CoV-2, with much early attention being paid to ...

New and Emerging Therapies for Reduction of LDL-Cholesterol and Apolipoprotein B: JACC ...
https://doi.org/10.1016/j.jacc.2020.11.079
Journal of the American College of Cardiology; Nurmohamed NS, Navar AM et. al.

Mar 26th, 2021 - Adding to the foundation of statins, ezetimibe and proprotein convertase subtilisin-kexin type 9 inhibitors (PCSK9i), novel, emerging low-density lipoprotein cholesterol (LDL-C)-lowering therapies are under development for the prevention of cardio...

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Guidelines  3 results

One Egg per Day Improves Inflammation when Compared to an Oatmeal-Based Breakfast without Increasing Other Cardiometabolic Risk Factors in Diabetic Patients
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446761/
Nutrients Ballesteros,M.,et al

May 10th, 2015 - There is concern that egg intake may increase blood glucose in patients with type 2 diabetes mellitus (T2DM). However, we have previously shown that eggs reduce inflammation in patients at risk for T2DM, including obese subjects and those with met...

Association of apolipoprotein B and nuclear magnetic resonance spectroscopy-derived LDL...
https://doi.org/10.1373/clinchem.2012.196733
Clinical Chemistry; , Cole TG et. al.

Feb 6th, 2013 - The number of circulating LDL particles is a strong indicator of future cardiovascular disease (CVD) events, even superior to the concentration of LDL cholesterol. Atherogenic (primarily LDL) particle number is typically determined either directly...

Apolipoprotein B and cardiovascular disease risk: position statement from the AACC Lipo...
https://doi.org/10.1373/clinchem.2008.118356
Clinical Chemistry; Contois JH, McConnell JP et. al.

Jan 26th, 2009 - Low-density lipoprotein cholesterol (LDL-C) has been the cornerstone measurement for assessing cardiovascular risk for nearly 20 years. Recent data demonstrate that apolipoprotein B (apo B) is a better measure of circulating LDL particle number (L...

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Drugs  11 results see all →

Clinicaltrials.gov  2,257 results

Per-Particle Triglyceride-Rich Lipoproteins Imply Higher Myocardial Infarction Risk Tha...
https://doi.org/10.1161/ATVBAHA.120.315639
Arteriosclerosis, Thrombosis, and Vascular Biology; Johansen MØ, Vedel-Krogh S et. al.

Apr 8th, 2021 - ApoB (Apolipoprotein B)-containing triglyceride-rich lipoproteins and LDL (low-density lipoproteins) are each causal for myocardial infarction and atherosclerotic cardiovascular disease; however, the relative importance is unknown. We tested the h...

Genetics of hypertriglyceridemia and atherosclerosis.
https://doi.org/10.1097/HCO.0000000000000839
Current Opinion in Cardiology; Gill PK, Dron JS et. al.

Apr 5th, 2021 - The relationship between elevated triglyceride levels (i.e. hypertriglyceridemia) and risk of atherosclerotic cardiovascular disease (ASCVD) has been investigated for decades. Recent genetic studies have sought to resolve the decades-old question ...

LDL/apo B ratio predict coronary heart disease in Type 2 diabetes independent of ASCVD ...
https://doi.org/10.1016/j.numecd.2021.01.013
Nutrition, Metabolism, and Cardiovascular Diseases : NMCD; Rabizadeh S, Rajab A et. al.

Apr 3rd, 2021 - Coronary heart disease (CHD) is a major mortality risk factor in patients with diabetes. LDL cholesterol (LDL-C) is a major risk factor for the development of atherosclerosis. There is one apolipoprotein B (ApoB) molecule in each LDL particle. We ...

Baseline cardiometabolic profiles and SARS-CoV-2 infection in the UK Biobank.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016301
PloS One; Scalsky RJ, Chen YJ et. al.

Apr 1st, 2021 - SARS-CoV-2 is a rapidly spreading coronavirus responsible for the Covid-19 pandemic, which is characterized by severe respiratory infection. Many factors have been identified as risk factors for SARS-CoV-2, with much early attention being paid to ...

New and Emerging Therapies for Reduction of LDL-Cholesterol and Apolipoprotein B: JACC ...
https://doi.org/10.1016/j.jacc.2020.11.079
Journal of the American College of Cardiology; Nurmohamed NS, Navar AM et. al.

Mar 26th, 2021 - Adding to the foundation of statins, ezetimibe and proprotein convertase subtilisin-kexin type 9 inhibitors (PCSK9i), novel, emerging low-density lipoprotein cholesterol (LDL-C)-lowering therapies are under development for the prevention of cardio...

see more →

News  67 results

Lipid Ratio Rules Out Pancreatitis Risk in Hypertriglyceridemia
https://www.staging.medscape.com/viewarticle/939205

Oct 14th, 2020 - Calculating the ratio between serum triglyceride and apolipoprotein B levels may help rule out patients with hypertriglyceridemia who are at low risk of developing hypertriglyceridemic pancreatitis (HTGP), and so better guide management, suggests ...

Lipid Ratio Rules Out Pancreatitis Risk in Hypertriglyceridemia
https://www.medscape.com/viewarticle/939205

Oct 14th, 2020 - Calculating the ratio between serum triglyceride and apolipoprotein B levels may help rule out patients with hypertriglyceridemia who are at low risk of developing hypertriglyceridemic pancreatitis (HTGP), and so better guide management, suggests ...

Bempedoic acid cuts LDL by 15% in patients already on maximal treatment
https://www.mdedge.com/cardiology/article/212279/lipid-disorders/bempedoic-acid-cuts-ldl-15-patients-already-maximal?channel=39313
Michele G. Sullivan

Nov 13th, 2019 - When added to maximally tolerated statin therapy, bempedoic acid reduced LDL cholesterol by more than 15%, compared with placebo, Anne C. Goldberg, MD, and colleagues reported in JAMA.

Early Evolocumab in Acute Coronary Syndrome Safe, LDL Plummets
https://www.medscape.com/viewarticle/917536

Aug 30th, 2019 - PARIS — Adding the PCSK9 inhibitor evolocumab (Repatha, Amgen) to high-intensity statin therapy in the very high-risk setting of acute coronary syndrome (ACS) safely lowers low-density lipoprotein cholesterol (LDL-C), according to the EVOPACS tria...

Do I Need to Care About Lp(a)?
https://www.staging.medscape.com/viewarticle/915036

Jul 7th, 2019 - Christopher Labos For the clinician who does not regularly wade into the cholesterol debate, it might be tempting to simply ignore lipoprotein(a) [Lp(a)]. After all, staying up to date with the cholesterol guidelines is no simple task. Targets for...

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