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About 4,615 results

ALLMedicine™ Apolipoprotein B Center

Research & Reviews  1,353 results

Diagnosis of remnant hyperlipidaemia.
https://doi.org/10.1097/MOL.0000000000000831
Current Opinion in Lipidology; Paquette M, Bernard S et. al.

Aug 10th, 2022 - In recent years, there has been interest for the development of simplified diagnosis algorithms of dysbetalipoproteinemia (DBL) in order to avoid the complex testing associated with the Fredrickson criteria (reference method). The purpose of this ...

Association between CYP2E1 C-1054T and 96-bp I/D genetic variations and the risk of pol...
https://doi.org/10.1007/s40618-022-01885-5
Journal of Endocrinological Investigation; Pu Y, Liu Q et. al.

Aug 10th, 2022 - To investigate the association of cytochrome P450 2E1 (CYP2E1) C-1054T (rs2031920) and 96-bp I/D genetic variations with the risk of polycystic ovary syndrome (PCOS), and to estimate the effects of genotypes on the clinical, metabolic, hormonal, a...

Short-term hyper-caloric high-fat feeding on a ketogenic diet can lower low-density lip...
https://doi.org/10.1097/MED.0000000000000762
Current Opinion in Endocrinology, Diabetes, and Obesity; Feldman D, Huggins S et. al.

Aug 9th, 2022 - Conventional knowledge holds that saturated fat is the primary dietary driver of increases in low-density lipoprotein-cholesterol (LDL-C), and that high LDL-C seen among some persons consuming low-carbohydrate, high-fat diets is driven by increase...

Monoclonal Autoantibody Against a Cryptic Epitope on Tissue-Adherent Low-Density Lipopr...
https://doi.org/10.1016/j.jcmg.2022.02.023
JACC. Cardiovascular Imaging; Khamis RY, Hartley A et. al.

Aug 5th, 2022 - Antibody-based constructs for molecular imaging and therapeutic delivery provide promising opportunities for the diagnosis and treatment of atherosclerosis. The authors aimed to generate and characterize immunoglobulin (Ig)G monoclonal autoantibod...

The Very Large Database of Lipids (VLDL)
https://clinicaltrials.gov/ct2/show/NCT01698489

Aug 3rd, 2022 - Closer examination of granular lipid data in a large population offers numerous opportunities to generate new knowledge, ranging from studies examining concordance between commonly used lipid parameters to phenotypic characterization of rare or ex...

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Guidelines  3 results

Menopause symptom management in women with dyslipidemias: An EMAS clinical guide.
https://doi.org/10.1016/j.maturitas.2020.03.007
Maturitas Anagnostis P, Bitzer J et. al.

Mar 27th, 2020 - Dyslipidemias are common and increase the risk of cardiovascular disease. The menopause transition is associated with an atherogenic lipid profile, with an increase in the concentrations of total cholesterol (TC) and low-density lipoprotein choles...

Association of apolipoprotein B and nuclear magnetic resonance spectroscopy-derived LDL...
https://doi.org/10.1373/clinchem.2012.196733
Clinical Chemistry; , Cole TG et. al.

Feb 7th, 2013 - The number of circulating LDL particles is a strong indicator of future cardiovascular disease (CVD) events, even superior to the concentration of LDL cholesterol. Atherogenic (primarily LDL) particle number is typically determined either directly...

Apolipoprotein B and cardiovascular disease risk: position statement from the AACC Lipo...
https://doi.org/10.1373/clinchem.2008.118356
Clinical Chemistry; Contois JH, McConnell JP et. al.

Jan 27th, 2009 - Low-density lipoprotein cholesterol (LDL-C) has been the cornerstone measurement for assessing cardiovascular risk for nearly 20 years. Recent data demonstrate that apolipoprotein B (apo B) is a better measure of circulating LDL particle number (L...

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Drugs  266 results see all →

Clinicaltrials.gov  91 results

The Very Large Database of Lipids (VLDL)
https://clinicaltrials.gov/ct2/show/NCT01698489

Aug 3rd, 2022 - Closer examination of granular lipid data in a large population offers numerous opportunities to generate new knowledge, ranging from studies examining concordance between commonly used lipid parameters to phenotypic characterization of rare or ex...

Time-restricted Eating to Improve Metabolic Abnormalities in Polycystic Ovarian Syndrome
https://clinicaltrials.gov/ct2/show/NCT05126199

Jun 3rd, 2022 - Background: Polycystic ovarian syndrome (PCOS) is the most common reproductive endocrinopathy in women of reproductive age with many associated metabolic symptoms, in particular hyperinsulinemia, insulin resistance and a high lifetime risk of type...

Abnormal Lipids - Causes and Effects
https://clinicaltrials.gov/ct2/show/NCT02195050

Jun 1st, 2022 - Fats are present in the body in the form of lipid particles containing cholesterol and triglycerides. Lipid particles can deposit in blood vessels, forming atheromas, blocking blood vessels and leading to heart attacks and strokes. These harmful p...

Effect of Molecular Hydrogen in Patients With NAFLD
https://clinicaltrials.gov/ct2/show/NCT05325398

Apr 13th, 2022 - Non-alcoholic fatty liver disease, NAFLD, is the most common cause of liver disease. According to the forecasts, the non-alcoholic steatohepatitis will be the most common cause of liver transplantation and hepatic mortality in 2030. NAFLD is also ...

Skeletal Muscle Mitochondrial Abnormalities and the Metabolic Syndrome in PAH
https://clinicaltrials.gov/ct2/show/NCT03979482

Apr 7th, 2022 - AIM 1: To determine whether MS is associated with intramuscular lipid accumulation and impaired skeletal muscle metabolism and perfusion in human PAH. Rationale: MS and IR are highly prevalent amongst PAH patients even in the absence of obesity an...

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News  133 results

Jul 8, 2022 This Week in Cardiology Podcast
https://www.medscape.com/viewarticle/976733

Jul 8th, 2022 - Please note that the text below is not a full transcript and has not been copyedited. For more insight and commentary on these stories, subscribe to the This Week in Cardiology podcast on Apple Podcasts, Spotify, or your preferred podcast provider...

Magnesium Claims for BP; S3 Ultra's Higher Gradients; Antiplatelets Flop in COVID
https://www.medpagetoday.com/cardiology/prevention/96729

Jan 18th, 2022 - Participants in the Framingham Study showed an increased lifetime risk of heart failure from 1965-1989 to 1990-2014. (Journal of the American College of Cardiology) A history of recent COVID-19 may warrant additional preoperative cardiac assessmen...

Lipid Levels Tied to ALS Risk
https://www.medscape.com/viewarticle/958730

Sep 14th, 2021 - Elevated levels of high-density lipoprotein (HDL) and apolipoprotein A1 (apoA1) are associated with a reduced risk for amyotrophic lateral sclerosis (ALS), new research shows. The study also linked a higher ratio of total cholesterol to HDL with a...

Targeted metabolomic profiling predicts CV risk in psoriasis and PsA
https://www.mdedge.com/rheumatology/article/242109/psoriatic-arthritis/targeted-metabolomic-profiling-predicts-cv-risk

Jun 24th, 2021 - Key clinical point: A range of novel metabolite markers associated with the risk for cardiovascular (CV) events when combined in a model matched with age and sex showed improved performance in predicting CV diseases in patients with psoriasis and.

An Expert's Guide to Managing Familial Hypercholesterolemia
https://www.medscape.com/viewarticle/948546

Apr 21st, 2021 - This transcript has been edited for clarity. Hi. I'm Seth Baum, a preventive cardiologist and clinical lipidologist in Boca Raton, Florida. I'm also the past president of the American Society for Preventive Cardiology and on the faculty at the Flo...

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