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About 7,710 results

ALLMedicine™ Homocysteine Center

Research & Reviews  2,839 results

The roles of homocysteinemia and methylmalonic acidemia in kidney injury in atypical he...
https://doi.org/10.1007/s00467-021-05372-6 10.1681/ASN.2004100861 10.1007/s00467-016-3399-0 10.1093/hmg/ddaa044 10.1016/j.ydbio.2020.09.005 10.1055/s-2000-8472 10.1007/s10545-007-0571-5 10.1038/ng1683 10.1172/JCI129937 10.1136/bcr-2015-211989 10.1007/s004310051190 10.1007/s00467-013-2443-6 10.3390/toxins11110660 10.1212/WNL.0000000000010912
Pediatric Nephrology (Berlin, Germany); Wood WD, Elmaghrabi A et. al.

Dec 3rd, 2021 - Cobalamin C (cblC), a vitamin B12 processing protein, plays a crucial role in metabolism for the conversion of homocysteine to methionine and methylmalonyl-CoA to succinyl-CoA. CblC deficiency, an inborn error of cobalamin processing, is a rare ca...

The Link between Exercise and Homocysteine in the Alzheimer's Disease: A Bioinformatic ...
https://doi.org/10.2174/1871527320666210706122618
CNS & Neurological Disorders Drug Targets; Leão LL, Felício LFF et. al.

Dec 3rd, 2021 - Elevated peripheral expression of homocysteine (Hcy) is associated with an increased risk of coronary heart disease and stroke, diabetes, and cancer. It is also associated with cognitive impairment as it has been reported that high levels of Hcy c...

Chronic insomnia in the setting of MTHFR polymorphism.
https://doi.org/10.5664/jcsm.9794
Journal of Clinical Sleep Medicine : JCSM : Official Publ... Kapoor V, Watson NF et. al.

Dec 2nd, 2021 - We present a patient with chronic insomnia resistant to traditional pharmacologic (e.g., sedative-hypnotics) and nonpharmacologic (e.g. cognitive behavioral therapy for insomnia; CBT-I) therapy. A finding of elevated serum homocysteine triggered a...

Long-Term Prognostic Implications and Role of Further Testing in Adults Aged ≤55 Years ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8607758
The American Journal of Cardiology; Cainzos-Achirica M, Acquah I et. al.

Nov 20th, 2021 - The long-term prognostic significance of a coronary artery calcium (CAC) score of 0 is poorly defined in younger adults. We evaluated this among participants aged 45 to 55 years from the Multi-Ethnic Study of Atherosclerosis, and assessed whether ...

Folic Acid Treatment for Patients with Vascular Cognitive Impairment: A Systematic Revi...
https://doi.org/10.1093/ijnp/pyab076
The International Journal of Neuropsychopharmacology; Gofir A, Wibowo S et. al.

Nov 19th, 2021 - As the life expectancy of elderly people has drastically increased, the incidence of cardiovascular and cerebrovascular diseases in this population has proportionally grown. Vascular cognitive impairment (VCI) refers to all forms of cognitive diso...

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Guidelines  1 results

Using nontraditional risk factors in coronary heart disease risk assessment: U.S. Preve...
https://doi.org/10.7326/0003-4819-151-7-200910060-00008
Annals of Internal Medicine;

Oct 7th, 2009 - New recommendation from the U.S. Preventive Services Task Force (USPSTF) on the use of nontraditional, or novel, risk factors in assessing the coronary heart disease (CHD) risk of asymptomatic persons. Systematic reviews were conducted of literatu...

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Drugs  15 results see all →

Clinicaltrials.gov  98 results

Homocysteine in Acute Coronary Syndrome
https://clinicaltrials.gov/ct2/show/NCT05125419

Nov 18th, 2021 - Cross sectional study to: assess homocysteine level in young adult patients presenting with acute coronary syndrome

Changing of Trace Element, Homocysteine, Oxidative Stress Parameters and Physical Activity Levels in Covid-19
https://clinicaltrials.gov/ct2/show/NCT04694703

Sep 16th, 2021 - Since December 2019, the new severe acute respiratory syndrome coronavirus 2, called SARS-CoV-2, has spread rapidly to almost every country that causes coronavirus disease-19 (COVID-19) pneumonia. Currently, there is no specific treatment for COVI...

Pegtibatinase as an Enzyme Therapy for Patients With Homocystinuria Caused by Cystathionine Beta-Synthase Deficiency (COMPOSE)
https://clinicaltrials.gov/ct2/show/NCT03406611

Sep 5th, 2021 - Homocystinuria caused by Cystathionine Beta-Synthase (CBS) Deficiency is a rare autosomal-recessive metabolic condition characterized by an excess of homocysteine (Hcy) in the plasma, tissues and urine. It is due to reduced or absent activity of t...

Insomnia Treated by Traditional Chinese Medicine and Its Circadian Rhythm
https://clinicaltrials.gov/ct2/show/NCT04448197

Aug 24th, 2021 - To record the demographic information and clinical characteristics of participants, including age, gender, education background, and drug use. Venous blood samples were collected and sent to laboratory test for blood routine, blood biochemistry, a...

Effectiveness of Comprehensive Tertiary Interventions on Incidence and Clinical Outcomes of Birth Defects
https://clinicaltrials.gov/ct2/show/NCT03725878

Aug 3rd, 2021 - According to World health Organization (WHO), approximately 3.2 million children are born with birth defect(s) worldwide and the incidence of birth defects in China is 5.6%. Birth defects are the main cause of fetal death, infant mortality and mor...

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News  131 results

High Maternal Lipid Levels Tied to Congenital Heart Disease in Offspring
https://www.medscape.com/viewarticle/958291

Sep 8th, 2021 - (Reuters Health) - Women with high lipid levels during early pregnancy are at increased risk for having offspring with congenital heart disease, a new study suggests. Researchers examined data on blood lipid levels during pregnancy for 230 women w...

Impact of the MTHFR C677T genetic variant on depression
https://www.mdedge.com/psychiatry/article/229111/depression/impact-mthfr-c677t-genetic-variant-depression
Madeline Lipp, PharmD, Amy Pasternak, PharmD et. al.

Oct 1st, 2020 - Ms. T, age 55, presents to her psychiatrist’s clinic with a chief complaint of ongoing symptoms of anhedonia and lethargy related to her diagnosis of major depressive disorder (MDD).

Alzheimer's May Develop Differently in Women
https://www.medpagetoday.com/neurology/alzheimersdisease/87246

Jun 24th, 2020 - Women developed Alzheimer's disease-related brain changes earlier than men, a cross-sectional imaging study showed. Compared with their male counterparts, cognitively normal middle-age women showed higher beta-amyloid loads, lower glucose metaboli...

Vegetarian Diet Linked to Lower Ischemic, Hemorrhagic Stroke Risk
https://www.staging.medscape.com/viewarticle/926113

Mar 3rd, 2020 - A vegetarian diet rich in nuts, vegetables, and soy has been linked to a lower risk of both ischemic and hemorrhagic stroke, new research suggests. In two large cohorts of more than 13,000 individuals, investigators found a vegetarian diet was ass...

Flow-mediated dilation of brachial artery predicts renal dysfunction in sickle cell disease
https://www.mdedge.com/hematology-oncology/article/216903/anemia/flow-mediated-dilation-brachial-artery-predicts-renal?channel=39313
Will Pass

Feb 7th, 2020 - Sonographic flow-mediated dilation (FMD) of the brachial artery predicts renal dysfunction in patients with sickle cell disease (SCD), according to investigators. Mohammed Haneefa Nizamudeen/Getty Images This is the first study to show that FMD –.

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