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About 8,800 results

ALLMedicine™ LDL Cholesterol Center

Research & Reviews  2,238 results

Lipid Lowering Effect of Plant Stanol Ester in a Drinkable Non-dairy Product
https://clinicaltrials.gov/ct2/show/NCT05126056

Dec 3rd, 2021 - The aim is to determine the effect of investigational products on serum LDL cholesterol.

An update on emerging drugs for the treatment of hypercholesterolemia.
https://doi.org/10.1080/14728214.2021.2009801
Expert Opinion on Emerging Drugs; Nelson AJ, Bubb K et. al.

Nov 30th, 2021 - Elevated levels of low-density lipoprotein (LDL) cholesterol have been unequivocally demonstrated to play a causal role in atherosclerotic cardiovascular disease. The last thirty years has witnessed a generation of clinical trials that have demons...

Efficacy and Safety of Atorvastatin + Perindopril Fixed-Dose Combination S05167 in Adult Patients With Arterial Hypertension and Dyslipidemia
https://clinicaltrials.gov/ct2/show/NCT04591808

Nov 30th, 2021 - The purpose of this study is to demonstrate the superiority of atorvastatin/perindopril fixed dose combination (FDC) S05167 as compared to atorvastatin reference drug alone or perindopril drug alone on systolic blood pressure decrease and LDL chol...

Implementation of a multi-level community-clinical linkage intervention to improve glyc...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609264
BMC Endocrine Disorders; Lim S, Wyatt LC et. al.

Nov 25th, 2021 - A number of studies have identified patient-, provider-, and community-level barriers to effective diabetes management among South Asian Americans, who have a high prevalence of type 2 diabetes. However, no multi-level, integrated community health...

PCSK9 Inhibitor Treatment for Patients With SPG5
https://clinicaltrials.gov/ct2/show/NCT04101643

Nov 23rd, 2021 - Spastic paraplegia type 5 (SPG5) is a rare subtype of hereditary spastic paraplegia, a highly heterogeneous group of neurodegenerative disorders defined by progressive neurodegeneration of the corticospinal tract motor neurons. SPG5 is caused by r...

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Guidelines  3 results

The 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guidelines on the Mana...
https://doi.org/10.2337/dci19-0036
Diabetes Care; Goldberg RB, Stone NJ et. al.

Jul 17th, 2020 - The American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines recently published its 2018 recommendations on management of LDL cholesterol (LDL-C) in people with diabetes. For primary prevention, moderate...

Quantifying atherogenic lipoproteins for lipid-lowering strategies: consensus-based rec...
https://doi.org/10.1515/cclm-2019-1253
Clinical Chemistry and Laboratory Medicine; Langlois MR, Nordestgaard BG et. al.

Dec 20th, 2019 - The joint consensus panel of the European Atherosclerosis Society (EAS) and the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) recently addressed present and future challenges in the laboratory diagnostics of atherogenic ...

Association of apolipoprotein B and nuclear magnetic resonance spectroscopy-derived LDL...
https://doi.org/10.1373/clinchem.2012.196733
Clinical Chemistry; , Cole TG et. al.

Feb 7th, 2013 - The number of circulating LDL particles is a strong indicator of future cardiovascular disease (CVD) events, even superior to the concentration of LDL cholesterol. Atherogenic (primarily LDL) particle number is typically determined either directly...

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Drugs  79 results see all →

Clinicaltrials.gov  141 results

Lipid Lowering Effect of Plant Stanol Ester in a Drinkable Non-dairy Product
https://clinicaltrials.gov/ct2/show/NCT05126056

Dec 3rd, 2021 - The aim is to determine the effect of investigational products on serum LDL cholesterol.

Efficacy and Safety of Atorvastatin + Perindopril Fixed-Dose Combination S05167 in Adult Patients With Arterial Hypertension and Dyslipidemia
https://clinicaltrials.gov/ct2/show/NCT04591808

Nov 30th, 2021 - The purpose of this study is to demonstrate the superiority of atorvastatin/perindopril fixed dose combination (FDC) S05167 as compared to atorvastatin reference drug alone or perindopril drug alone on systolic blood pressure decrease and LDL chol...

PCSK9 Inhibitor Treatment for Patients With SPG5
https://clinicaltrials.gov/ct2/show/NCT04101643

Nov 23rd, 2021 - Spastic paraplegia type 5 (SPG5) is a rare subtype of hereditary spastic paraplegia, a highly heterogeneous group of neurodegenerative disorders defined by progressive neurodegeneration of the corticospinal tract motor neurons. SPG5 is caused by r...

LIPId Profile Changes in Inflammatory Conditions Induced by SARS-CORoronavirus-2
https://clinicaltrials.gov/ct2/show/NCT05113836

Nov 9th, 2021 - In late 2019, a new coronavirus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was identified as the cause of COVID-19 (COronaVIrus Disease-2019) in Hubei Province, China. COVID-19 has become a pandemic with approximately 4.1 ...

Cost-effectiveness of the Care Pathways
https://clinicaltrials.gov/ct2/show/NCT04619836

Oct 19th, 2021 - The study recruits 270 adult-type diabetics and 200 clients of substance abuse services for each of the four client segments (self-employment, community, cooperation, network client) and the comparison group. Based on previous evaluations and stud...

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News  1,053 results

Familial Hypercholesterolemia — Hiding in Plain Sight
https://www.medscape.com/viewarticle/958283

Oct 21st, 2021 - This transcript has been edited for clarity. Laurence Sperling, MD: Welcome to the Medscape InDiscussion podcast series on dyslipidemia. This is the first of six episodes. To launch this series today, we will focus on an extremely important topic:...

Longer Exposure to Elevated LDL Tied to Higher CHD Risk
https://www.medscape.com/viewarticle/960460

Oct 7th, 2021 - Higher exposure to LDL cholesterol (LDL-C) during young adulthood and middle age is associated with a significantly higher risk of coronary heart disease (CHD), regardless of midlife lipid levels, new research suggests. Investigators analyzed pool...

Familial Hypercholesterolemia Diagnosed Late, LDL Control Far Below Recommendations
https://www.medscape.com/viewarticle/959861

Sep 30th, 2021 - NEW YORK (Reuters Health) - Globally, familial hypercholesterolemia (FH) is diagnosed late, and control of LDL cholesterol in patients is far below recommendations, a new analysis shows. "Guideline-recommended LDL cholesterol concentrations are in...

Setting Global Diabetes Targets Could Save Lives
https://www.medpagetoday.com/endocrinology/diabetes/94649

Sep 22nd, 2021 - Setting global targets for treating diabetes in lower-income countries, similar to the targets set for HIV/AIDS, would save lives and decrease medical care costs, researchers said. An analysis of data on over 23,000 patients with diabetes from 67 ...

Early Cholesterol Levels Matter for Later-Life Events
https://www.medpagetoday.com/cardiology/dyslipidemia/94636

Sep 22nd, 2021 - LDL cholesterol (LDL-C) exposure in younger adulthood predicted later cardiovascular events independent of cholesterol in middle age, large observational cohorts showed. Coronary heart disease significantly correlated with cumulative LDL-C (HR 1.5...

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Patient Education  6 results see all →