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About 658 results

ALLMedicine™ Serum Osteocalcin Center

Research & Reviews  242 results

Radiation Medication (Radium-223 Dichloride) Versus Radium-223 Dichloride Plus Radiation Enhancing Medication (M3814) Versus Radium-223 Dichloride Plus M3814 Plus Avelumab (a Type of Immunotherapy)...
https://clinicaltrials.gov/ct2/show/NCT04071236

Jun 23rd, 2022 - PRIMARY OBJECTIVES: I. To determine the maximum tolerated dose (MTD) of peposertib (M3814) in combination with radium-223 dichloride or in combination with radium-223 dichloride and avelumab in patients with advanced metastatic castrate-resistant ...

Testing the Addition of Radium Therapy (Radium-223 Dichloride) to the Usual Chemotherapy Treatment (Paclitaxel) for Advanced Breast Cancer That Has Spread to the Bones
https://clinicaltrials.gov/ct2/show/NCT04090398

Jun 22nd, 2022 - PRIMARY OBJECTIVE: I. To determine if the combination of radium Ra 223 dichloride (radium-223 dichloride) and paclitaxel improves progression-free survival (PFS) compared to paclitaxel alone. SECONDARY OBJECTIVES: I. To determine the time to the f...

One-Year Mean A1c of > 7% is Associated with Poor Bone Microarchitecture and Strength i...
https://doi.org/10.1007/s00223-022-00993-x 10.1016/j.diabres.2019.107843 10.1359/jbmr.2003.18.4.784 10.1210/jc.2008-0639 10.1359/JBMR.040311 10.2147/TCRM.S131945 10.1002/jbmr.3002 10.2337/dc06-0440 10.1007/s001250051248 10.1007/s00198-006-0253-4 10.2105/AJPH.79.3.274 10.1093/oxfordjournals.aje.a116756 10.1016/j.bone.2017.03.039 10.1038/nrendo.2016.153 10.1016/j.bone.2015.07.027 10.1111/joim.12725 10.1007/s00198-005-1877-5 10.1185/03007990902801147 10.1210/jc.2010-0226 10.1002/jbmr.2106 10.1002/jbmr.2388 10.1002/jbmr.3240 10.1371/journal.pone.0035047 10.1016/S8756-3282(00)00434-8 10.1016/j.bone.2005.07.019 10.1186/s13098-017-0278-1 10.1186/s12902-017-0224-0 10.1038/boneres.2016.1 10.1210/jc.2012-1546 10.2337/dc12-1188 10.1002/jbmr.2462 10.1210/jendso/bvab048.560 10.1016/S0140-6736(98)07019-6 10.1016/S0140-6736(98)07037-8 10.2337/dc21-S006 10.3389/fendo.2020.00277 10.1210/clinem/dgab061 10.1210/js.2019-MON-094 10.1016/j.conctc.2021.100723 10.1038/ijir.2009.35 10.7573/dic.212607 10.1530/EJE-14-1103 10.1002/jbmr.2176 10.1002/jbmr.297 10.1016/S8756-3282(02)00736-6 10.1210/jc.2018-00229 10.1053/j.gastro.2007.04.068 10.1055/s-2006-923886 10.1038/nrendo.2017.151 10.1001/jama.295.11.1288 10.3389/fphys.2014.00137 10.1002/jcb.10220 10.1016/S8756-3282(02)00866-9 10.1002/jbmr.3057 10.1002/jbmr.3711 10.1016/j.bone.2017.05.004 10.1016/j.jbiomech.2007.09.003 10.1016/j.jbiomech.2018.11.030 10.1016/j.diabres.2016.03.009 10.1111/j.1532-5415.2012.04052.x
Calcified Tissue International; Ballato E, Deepika FNU et. al.

Jun 7th, 2022 - Type 2 diabetes mellitus (T2DM) is associated with normal or slightly elevated bone mineral density (BMD) but paradoxically increased fracture risk. Although multiple mechanisms have been proposed to explain this observation, one thing is clear fr...

Effect of active vitamin D treatment on development of type 2 diabetes: DPVD randomised...
https://doi.org/10.1136/bmj-2021-066222
BMJ (Clinical Research Ed.); Kawahara T, Suzuki G et. al.

May 26th, 2022 - To assess whether eldecalcitol, an active vitamin D analogue2, can reduce the development of type 2 diabetes among adults with impaired glucose tolerance. Double blinded, multicentre, randomised, placebo controlled trial. Three hospitals in Japan,...

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Clinicaltrials.gov  16 results

Radiation Medication (Radium-223 Dichloride) Versus Radium-223 Dichloride Plus Radiation Enhancing Medication (M3814) Versus Radium-223 Dichloride Plus M3814 Plus Avelumab (a Type of Immunotherapy)...
https://clinicaltrials.gov/ct2/show/NCT04071236

Jun 23rd, 2022 - PRIMARY OBJECTIVES: I. To determine the maximum tolerated dose (MTD) of peposertib (M3814) in combination with radium-223 dichloride or in combination with radium-223 dichloride and avelumab in patients with advanced metastatic castrate-resistant ...

Testing the Addition of Radium Therapy (Radium-223 Dichloride) to the Usual Chemotherapy Treatment (Paclitaxel) for Advanced Breast Cancer That Has Spread to the Bones
https://clinicaltrials.gov/ct2/show/NCT04090398

Jun 22nd, 2022 - PRIMARY OBJECTIVE: I. To determine if the combination of radium Ra 223 dichloride (radium-223 dichloride) and paclitaxel improves progression-free survival (PFS) compared to paclitaxel alone. SECONDARY OBJECTIVES: I. To determine the time to the f...

Effect of Fatty Liver Disease on Bone Density
https://clinicaltrials.gov/ct2/show/NCT04850547

Apr 20th, 2021 - All included patients will be subjected to the following: Complete history taking including age, sex, current medical history (e.g. hypertension, diabetes mellitus, cardiovascular disease, renal, thyroid, parathyroid diseases and menopausal status...

Beijing Osteoporosis With Neurological Disorders in Epigenetic Changes Study
https://clinicaltrials.gov/ct2/show/NCT03401619

Sep 17th, 2020 - Epigenetic modification refers to the change of heritable gene expression occurring in the case of unchanged DNA sequence, including DNA methylation, epigenetic modification, RNAS, chromatin modification, etc. The study found that osteoporosis (OS...

CORT125134 Single Ascending Dose (SAD) and Multiple Ascending Dose (MAD)
https://clinicaltrials.gov/ct2/show/NCT03508635

Aug 9th, 2019 - This is a 3-part, single-center study of single and multiple ascending doses of CORT125134 in healthy participants. Part I is a single dose study. Initially, participants will be enrolled sequentially into 1 of up to 6 cohorts, each containing 10 ...

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News  5 results

Effects of IV bisphosphonates last 2-3 years in children
https://www.mdedge.com/endocrinology/article/84311/osteoporosis/effects-iv-bisphosphonates-last-2-3-years-children
M. Alexander Otto

Jul 7th, 2014 - CHICAGO – Serum osteocalcin is the first bone turnover marker to recover after intravenous bisphosphonate therapy in children with primary osteoporosis, secondary osteoporosis, or osteogenesis imperfecta, making it a good indicator that it’s time.

Altered Calcium Metabolism After Bariatric Surgery Prompts Bone Loss
https://www.medpagetoday.com/primarycare/obesity/11027

Sep 23rd, 2008 - Action Points Explain to interested patients that the study suggested that bariatric surgery for obesity impairs absorption of calcium and disrupts other factors important for bone health. Explain that the study found that decreased bone mineral d...

Expert Lists Pros and Cons Of Bone Turnover Markers
https://www.mdedge.com/rheumatology/article/43008/osteoarthritis/expert-lists-pros-and-cons-bone-turnover-markers

SAN DIEGO — A chief advantage of assessing bone turnover markers such as serum osteocalcin and urine hydroxyproline in osteoporosis patients is that they provide an integrated assessment of skeletal metabolism, Dr. Marc C.

Bone Turnover Markers Show The Big Picture
https://www.mdedge.com/familymedicine/article/27463/rheumatology/bone-turnover-markers-show-big-picture
Family Practice News;

SAN DIEGO — A chief advantage of assessing bone turnover markers such as serum osteocalcin and urine hydroxyproline in osteoporosis patients is that they provide an integrated assessment of skeletal metabolism, Dr. Marc C.

Vitamin D Levels in Elders
https://www.medscape.com/viewarticle/703976

Most older people had low serum levels, and at least 25% of elders had frank vitamin D deficiency. Two studies in the Journal of Clinical Endocrinology and Metabolism focus on vitamin D in older populations. Researchers measured serum 25-hydroxyvi...

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