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About 678 results

ALLMedicine™ 17-hydroxyprogesterone Center

Research & Reviews  246 results

17-Ketosteroids
http://emedicine.medscape.com/article/2089246-overview

May 13th, 2022 - Reference Range The reference range of urinary 17-ketosteroids is as follows [1] : Males: 10-20 mg (34-69 µmol)/24 h Females: 5-15 mg (17-52 µmol)/24 h Next: Interpretation Increases in levels of 24-hour urinary 17-ketosteroids are associated with...

17-Ketosteroids
https://emedicine.medscape.com/article/2089246-overview

May 13th, 2022 - Reference Range The reference range of urinary 17-ketosteroids is as follows [1] : Males: 10-20 mg (34-69 µmol)/24 h Females: 5-15 mg (17-52 µmol)/24 h Next: Interpretation Increases in levels of 24-hour urinary 17-ketosteroids are associated with...

Progesterone activates GPR126 to promote breast cancer development via the Gi pathway.
https://doi.org/10.1073/pnas.2117004119
Proceedings of the National Academy of Sciences of the Un... An W, Lin H et. al.

Apr 9th, 2022 - GPR126 is a member of the adhesion G protein-coupled receptors (aGPCRs) that is essential for the normal development of diverse tissues, and its mutations are implicated in various pathological processes. Here, through screening 34 steroid hormone...

Insights into Interactions of Human Cytochrome P450 17A1: Review.
https://doi.org/10.2174/1389200223666220401093833
Current Drug Metabolism; Singh H, Kumar R et. al.

Apr 4th, 2022 - Cytochrome P450s are a widespread and vast superfamily of hemeprotein monooxygenases that metabolize physiologically essential chemicals necessary for most species' survival, from protists to plants to humans. They catalyze the synthesis of steroi...

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Clinicaltrials.gov  10 results

Androgen Reduction in Congenital Adrenal Hyperplasia, Phase 1
https://clinicaltrials.gov/ct2/show/NCT02574910

Feb 24th, 2022 - Congenital adrenal hyperplasia (CAH) is an inherited inability to synthesize cortisol in the adrenal gland. More than 90% of cases are cause by deficiency of steroid 21-hydroxylase (CYP21, also termed CYP21A2, P450c21), which is a cytochrome P450 ...

Androgen Reduction in Congenital Adrenal Hyperplasia
https://clinicaltrials.gov/ct2/show/NCT03548246

Dec 20th, 2021 - Congenital adrenal hyperplasia (CAH) is an inherited inability to synthesize cortisol in the adrenal gland. More than 90% of cases are cause by deficiency of steroid 21-hydroxylase (CYP21, also termed CYP21A2, P450c21), which is a cytochrome P450 ...

Ovarian Morphology and Theca Cell Androgen Production in Women With Polycystic Ovary Syndrome (PCOS)
https://clinicaltrials.gov/ct2/show/NCT02145247

Aug 12th, 2019 - In women with polycystic ovary syndrome (PCOS), the major abnormality is excessive ovarian androgen production marked by increased serum testosterone (T) and androstenedione (A) levels. Studies to determine the alteration in ovarian steroidogenesi...

Early Luteal Progesterone Profile in IVF Patients Triggered With hCG
https://clinicaltrials.gov/ct2/show/NCT03174691

Aug 6th, 2019 - The early luteal phase after IVF treatment is only scarcely studied. During IVF treatment the early luteinizing hormone (LH) activity deficit induced after ovarian stimulation with exogenous gonadotropins will be partly covered by the bolus of hCG...

Theca Cell Function in Adolescents With Polycystic Ovary Syndrome (PCOS)
https://clinicaltrials.gov/ct2/show/NCT01154192

Apr 30th, 2019 - In women with polycystic ovary syndrome (PCOS), the cardinal physiological abnormality is excessive ovarian androgen production marked by increased serum testosterone (T) and androstenedione (A) levels. Studies to determine the alteration in ovari...

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News  15 results

Polycystic Ovary Syndrome: It’s Not Just About Fertility
https://www.medscape.com/viewarticle/951631

May 21st, 2021 - Polycystic ovary syndrome, the most common endocrinopathy and most common cause of female infertility, affects 8%-13% of reproductive-aged women. PCOS has a profound impact on a woman’s life yet its diagnosis and management remain confusing despit...

Polycystic ovary syndrome: It’s not just about fertility
https://www.mdedge.com/obgyn/article/240396/reproductive-endocrinology/polycystic-ovary-syndrome-its-not-just-about
Mark P. Trolice, MD

May 20th, 2021 - Polycystic ovary syndrome, the most common endocrinopathy and most common cause of female infertility, affects 8%-13% of reproductive-aged women. PCOS has a profound impact on a woman’s life yet its diagnosis and management remain confusing despit.

CBD Oil for Epilepsy Linked to Early Onset of Puberty in 2-Year-Old
https://www.medscape.com/viewarticle/950260

May 3rd, 2021 - NEW YORK (Reuters Health) - Researchers from the U.K. are reporting a case of early puberty in a 2-year-old boy who was given cannabidiol (CBD) oil his mother purchased online to help control epileptic seizures. The start of puberty before the age...

Call for FDA to Withdraw Preterm Birth Drug Divides Doctors and Insurers
https://www.staging.medscape.com/viewarticle/924366

Jan 28th, 2020 - Doctors fear that the only drug approved to prevent preterm birth, the nation's leading cause of infant mortality and disability, will no longer be available to expectant mothers. The drug, sold under the brand name Makena, has been in limbo since...

Call for FDA to Withdraw Preterm Birth Drug Divides Doctors and Insurers
https://www.medscape.com/viewarticle/924366

Jan 28th, 2020 - Doctors fear that the only drug approved to prevent preterm birth, the nation's leading cause of infant mortality and disability, will no longer be available to expectant mothers. The drug, sold under the brand name Makena, has been in limbo since...

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