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ALLMedicine™ C-peptide Center

Research & Reviews  2,371 results

ABCC8-Related Maturity-Onset Diabetes of the Young: Clinical Features and Genetic Analy...
https://doi.org/10.1111/pedi.13388
Pediatric Diabetes; Zhou Y, Sun Y et. al.

Jun 28th, 2022 - To confirm the diagnosis of a 13-year-old adolescent with familial diabetes and further examine his genetic pathogeny. Clinical data were collected, and genetic examination was performed. PolyPhen-2 and Mutation Taster were used to predict the del...

Case report: hypoglycemia secondary to methimazole-induced insulin autoimmune syndrome ...
https://doi.org/10.1097/MD.0000000000029337
Medicine Wu HY, Chen IH et. al.

Jun 28th, 2022 - Hypoglycemia is an emergent condition with many causes, including underlying diabetes mellitus either with the use of insulin or oral anti-diabetic medications for glucose control, and organ (heart, hepatic, or renal) failure. Insulin autoimmune s...

Early-phase insulin hypersecretion associated with weight loss outcome after LSG: a pro...
https://doi.org/10.1016/j.soard.2022.05.013
Surgery for Obesity and Related Diseases : Official Journ... Guo L, Luo W et. al.

Jun 25th, 2022 - Obesity has become a global problem that poses a serious threat to human health. Laparoscopic sleeve gastrectomy (LSG) is an effective long-term treatment. However, the weight loss of some patients after LSG is still insufficient. It is necessary ...

Familial diabetes predisposes PCOS patients to insulin resistance (IR), reproductive im...
https://doi.org/10.1080/09513590.2022.2089107
Gynecological Endocrinology : the Official Journal of The... Genazzani AD, Battipaglia C et. al.

Jun 25th, 2022 - PCOS is a syndrome is characterized by 2 out of 3 of the criteria established during the Rotterdam Consensus Conference. Recently the issue of insulin resistance (IR) has caught attention. A group of overweight/obese PCOS patients (n = 30) have be...

Characterization of Insulin-like Peptide (ILP) and Its Potential Role in Ovarian Develo...
https://doi.org/10.3390/cimb44060170
Current Issues in Molecular Biology; Lü Z, Yao C et. al.

Jun 24th, 2022 - The insulin-like peptide (ILP) family is well known for regulating reproduction in invertebrates, while its role in mollusks remains largely unknown. In this study, we first isolated and characterized the ILP gene in the cuttlefish Sepiella japoni...

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Clinicaltrials.gov  430 results

Ixekizumab Diabetes Intervention Trial (I-DIT)
https://clinicaltrials.gov/ct2/show/NCT04589325

Jun 22nd, 2022 - In this double-blind, placebo-controlled prospective trial, patients with newly diagnosed T1D will be randomized to receive either Ixekizumab or placebo in addition to their conventional therapy. The primary aim is to examine the effect of Ixekizu...

Assessing the Impact of INSTI to PI Switch on Insulin Sensitivity and Fat Metabolism
https://clinicaltrials.gov/ct2/show/NCT04675255

Jun 21st, 2022 - Synopsis Full study title: Assessing the impact of integrase strand transfer inhibitors (INSTI) to protease inhibitor (PI) switch on insulin sensitivity and fat metabolism (ADIPOSITY): a sub-study of DEFINE Endpoints and objectives: The following ...

Acupuncture or Metformin for Insulin Resistance in Women With PCOS
https://clinicaltrials.gov/ct2/show/NCT02647827

Jun 16th, 2022 - Specific Aims The purpose of the study is to perform a randomized controlled trial of women with PCOS, comparing the effectiveness of lifestyle management alone, and in combination with acupuncture or metformin treatment on whole body glucose home...

Low-dose IL-2 in Established T1D - The "PROREG" Study
https://clinicaltrials.gov/ct2/show/NCT03243058

Jun 15th, 2022 - Randomized, controlled, double-blinded, multicenter, phase I/II clinical trial to evaluate the safety of low-dose IL-2 and determine whether low-dose IL-2 therapy for one year, can prevent further loss of beta-cell function in patients with establ...

Time Limited Eating in Type 1 Diabetes
https://clinicaltrials.gov/ct2/show/NCT05031429

Jun 15th, 2022 - This will be a two-armed study with an intervention and control group. Feasibility and acceptability will be assessed by using questionnaires. Safety will be indicated by hypoglycemia occurrence. β-cell function and insulin sensitivity will be eva...

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News  145 results

Trending Clinical Topic: Vitamin D
https://www.medscape.com/viewarticle/973641

Jun 10th, 2022 - Each week, we identify one top search term, speculate about what caused its popularity, and provide an infographic on a related condition. If you have thoughts about what's trending and why, share them with us on Twitter or Facebook.  Experts have...

Quadruple therapy as attractive as once-weekly GLP-1RA therapy in poorly controlled T2D
https://www.mdedge.com/type-2-diabetes-icymi/article/254938/diabetes/quadruple-therapy-attractive-once-weekly-glp-1ra

May 24th, 2022 - Key clinical point: Treatment intensification with quadruple therapy showed similar glucose lowering efficacy as once weekly glucagon-like peptide-1 receptor agonist (GLP-1RA)-based triple therapy in patients with poorly controlled type 2 diabetes.

Vitamin D Shows Pancreatic Dysfunction Link in T2D With Obesity
https://www.medscape.com/viewarticle/973305

May 2nd, 2022 - Researchers published the study covered in this summary on researchsquare.com as a preprint that has not yet been peer reviewed. Key Takeaways Levels of 25-hydroxyvitamin D (25[OH]D), also known as vitamin D3 and the major circulating form of vita...

Type 1 Diabetes Not Just a Childhood-Onset Disease
https://www.medscape.com/viewarticle/971840

Apr 11th, 2022 - NEW YORK (Reuters Health) - Despite popular belief that type-1 diabetes (T1D) is a disease that starts in childhood, its onset in adults is substantial, researchers report. A review of population- based studies looking at adult-onset T1D revealed ...

Stem Cell-Derived Pancreatic Cells May Be Alternative to Islet Transplants
https://www.medscape.com/viewarticle/966794

Jan 20th, 2022 - NEW YORK (Reuters Health) - An ongoing first-in-human trial suggests that pancreatic cells grown from stem cells can be safely implanted into patients with type 1 diabetes, and in some cases, begin producing insulin. "I was surprised by how well t...

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