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Research & Reviews  229 results

Adrenalectomy improves blood pressure control in nonfunctioning adrenal incidentalomas ...
https://doi.org/10.1007/s12020-022-03120-w 10.1530/EJE-16-0467 10.1016/j.endinu.2020.03.002 10.1159/000443862 10.1530/EJE-16-0465 10.1210/jc.2009-2387 10.1007/s40292-017-0182-7 10.1097/SLA.0b013e31819a47d2 10.3389/fendo.2022.898084 10.1530/EJE-11-1039 10.1016/j.metabol.2010.01.007 10.3275/6431 10.4158/EP-2020-0182 10.1007/s12020-021-02741-x 10.1016/j.endinu.2019.01.007 10.4103/ijem.IJEM-52-19 10.1055/s-0042-109866 10.1038/s41371-017-0011-4 10.1530/eje.0.1480213 10.1046/j.1365-2265.2001.01274.x 10.1016/j.jbi.2008.08.010 10.1007/s12020-019-01888-y 10.1210/JC.2001-011766 10.1210/jc.2013-3527 10.1210/JCEM.85.4.6515 10.3803/ENM.2014.29.4.457 10.1016/S2213-8587(13)70211-0 10.1111/cen.13294 10.1007/s12020-019-02066-w 10.1161/01.HYP.36.5.912 10.1016/j.tem.2011.09.001 10.1007/s40618-021-01539-y 10.1007/s12020-012-9622-2 10.1111/j.1365-2265.2008.03492.x 10.1111/j.1365-2265.2010.03963.x 10.1530/EJE-13-0848 10.3389/fendo.2021.794197 10.1016/j.surg.2012.08.054 10.1007/S00268-014-2482-6 10.1507/endocrj.K07E-177 10.1007/s40618-014-0232-0 10.1111/j.1365-2796.2010.02291.x 10.1007/s12020-009-9260-5 10.1210/jc.2013-4064 10.1007/s12020-020-02544-6 10.1007/s40618-014-0106-5 10.1210/jc.2008-0125
Endocrine Araujo-Castro M, Mínguez Ojeda C et. al.

Jun 26th, 2022 - To compare the evolution of the cardiometabolic parameters in patients with nonfunctioning adrenal incidentalomas (NFAI) and autonomous cortisol secretion (ACS) who underwent adrenalectomy and those who were conservatively managed. A retrospective...

Whom should we screen for Cushing's syndrome: The Endocrine Society Practice Guideline ...
The Journal of Clinical Endocrinology and Metabolism; Braun LT, Vogel F et. al.

Jun 23rd, 2022 - Cushing's syndrome (CS) is a rare and serious disease with high mortality. Patients are often diagnosed late in the course of the disease. Whether defined patient populations should be screened outside the at risk populations defined in current gu...

Autonomous cortisol secretion is associated with worse arterial stiffness and vascular ...
European Journal of Endocrinology; Tsai CH, Liao CW et. al.

May 14th, 2022 - The presence of autonomous cortisol secretion (ACS) in patients with primary aldosteronism (PA) is common and potentially associated with poor outcomes. The aim of this study was to investigate the association between ACS and vascular remodeling i...

Age-dependent and sex-dependent disparity in mortality in patients with adrenal inciden...
The Lancet. Diabetes & Endocrinology; Deutschbein T, Reimondo G et. al.

May 10th, 2022 - The association between cortisol secretion and mortality in patients with adrenal incidentalomas is controversial. We aimed to assess all-cause mortality, prevalence of comorbidities, and occurrence of cardiovascular events in uniformly stratified...

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Drugs  2 results see all →

Clinicaltrials.gov  13 results

Association Between Stroke and Adrenal Incidentalomas

Feb 14th, 2022 - Background: Adrenal incidentalomas (AIs) are commonly encountered in transsection imaging which purpose not for suspected adrenal disease. However, part of AIs in patients is associated with Stroke . The investigators aimed to investigate the risk...

Discriminant Capacity and Thresholds of Salivary Cortisol in Chemiluminescence in the Diagnosis of Hypercorticisms

Oct 5th, 2021 - Automated immunodosage methods (Roche Elecsys cortisol and IDS cortisol dosing kits) offer a simple and inexpensive technology routinely used in a medical biology laboratory. They can be used to define robust diagnostic thresholds for salivary cor...

Morbidity and Mortality in Autonomous Cortisol Secretion

Mar 26th, 2021 - Patients with adrenal adenomas may have autonomous cortisol secretion (ACS) that has been linked to hypertension, diabetes, dyslipidemia and cardiovascular disease. Patients with ACS also have been found to have increased mortality. In two studies...

Effects of Interleukin-1 Receptor Antagonism on Hyperandrogenemia in Women With Polycystic Ovary Syndrome

Jan 27th, 2021 - A prospective, interventional, open-label, single-arm, proof-of-concept study: 18 women with Polycystic Ovary Syndrome (PCOS) will be treated with 100 mg of Anakinra/Kineret® for 4 weeks. 1 week after last injection patients will have a follow-up ...

Effects of the Addition of Metyrapone to Antidepressant Therapy in Depression With Dexamethasone Suppression Test Non-suppression.

Sep 9th, 2020 - Depression is now a public health issue, concerning 300 billion people in the World it is the leading cause of disability according to the World Health Organization and 800 000 persons die each year by committing suicide. Despite the finding of sp...

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News  17 results

Mild Cortisol Excess Increases Mortality in Adrenal Incidentaloma

May 24th, 2021 - Mortality is two to three times higher in patients with adrenal incidentalomas who have autonomous cortisol secretion levels of 83 nmol/L (3 µg/dL) or more after a 1 mg dexamethasone suppression test (DST) compared with those with levels below thi...

Mysterious Femur Fracture in a Middle-Aged Man

Apr 6th, 2018 - Physical Examination and Workup Upon physical examination, his vital signs are normal. His height is about the same length as his arm span. The patient's physical appearance is remarkable for HIV-treatment–induced lipodystrophy and a Cushingoid ha...

A 36-Year-Old Man With Fatigue, Increased Thirst, and Leg Cramps

Feb 9th, 2017 - The constellation of worsening glycemic control, hypertension, hypokalemia, and weight gain strongly supports the diagnosis of Cushing syndrome. In this particular case, the elevated ACTH level did not indicate a cortisol-producing adrenal tumor, ...

Fast Five Quiz: Are You Prepared to Confront Seasonal Affective Disorder?

Nov 23rd, 2016 - No diagnostic laboratory tests are available, but focused laboratory studies may be useful to exclude potential medical illnesses. These laboratory studies include the following: Complete blood cell (CBC) count Thyroid-stimulating hormone Vitamin ...

Genetic and related laboratory tests in psychiatry: What mental health practitioners need to know
Sheldon H. Preskorn, MD

Mar 28th, 2016 - What has been the history of the development of laboratory tests in the field of psychiatry? During my almost-40-year academic medical career, I have been interested in the development and incorporation of laboratory tests into psychiatry. 1 This i.

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