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About 13,257 results

AllMedicine Bilirubin Center

Research & Reviews  6,345 results

Liver Structure and Function - Hepatic and Biliary Disorders - Merck Manuals Professional Edition
https://www.merckmanuals.com/professional/hepatic-and-biliary-disorders/approach-to-the-patient-with-liver-disease/liver-structure-and-function

Jan 1st, 2018 - The liver is the most metabolically complex organ. Hepatocytes (liver parenchymal cells) perform the liver’s metabolic functions: Formation and excretion of bile during bilirubin metabolism (see Overview of Bilirubin Metabolism) Regulation of ...

ACG Clinical Guideline: Evaluation of Abnormal Liver Chemistries
https://journals.lww.com/ajg/pages/articleviewer.aspx?year=2017&issue=01000&article=00013&type=Fulltext
The American Journal of Gastroenterology; Kwo, P. et. al.

Jun 30th, 2017 - Clinicians are required to assess abnormal liver chemistries on a daily basis. The most common liver chemistries ordered are serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase and bilirubin. These tests sh...

Risk of Autism Associated With Hyperbilirubinemia and Phototherapy.
https://doi.org/10.1542/peds.2016-1813
Pediatrics Wu YW, Kuzniewicz MW et. al.

Sep 27th, 2016 - Whether neonatal hyperbilirubinemia and/or phototherapy increase the risk of autism spectrum disorder (ASD) is unclear. We sought to quantify the risk of ASD associated with elevated total serum bilirubin (TSB) levels and with phototherapy. In a r...

Utility of Decision Rules for Transcutaneous Bilirubin Measurements.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845868
Pediatrics Taylor JA, Burgos AE et. al.

May 31st, 2016 - Transcutaneous bilirubin (TcB) meters are widely used for screening newborns for jaundice, with a total serum bilirubin (TSB) measurement indicated when the TcB value is classified as "positive" by using a decision rule. The goal of our study was ...

Association Between Laboratory Calibration of a Serum Bilirubin Assay, Neonatal Bilirub...
https://doi.org/10.1001/jamapediatrics.2015.4944
JAMA Pediatrics; Kuzniewicz MW, Greene DN et. al.

Apr 11th, 2016 - The American Academy of Pediatrics treatment recommendations for neonatal jaundice are based on age-specific total serum bilirubin (TSB) levels. In May 2012, Ortho Clinical Diagnostics adjusted the calibrator values for Vitros Chemistry Products B...

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Guidelines  11 results

Liver Structure and Function - Hepatic and Biliary Disorders - Merck Manuals Professional Edition
https://www.merckmanuals.com/professional/hepatic-and-biliary-disorders/approach-to-the-patient-with-liver-disease/liver-structure-and-function

Jan 1st, 2018 - The liver is the most metabolically complex organ. Hepatocytes (liver parenchymal cells) perform the liver’s metabolic functions: Formation and excretion of bile during bilirubin metabolism (see Overview of Bilirubin Metabolism) Regulation of ...

ACG Clinical Guideline: Evaluation of Abnormal Liver Chemistries
https://journals.lww.com/ajg/pages/articleviewer.aspx?year=2017&issue=01000&article=00013&type=Fulltext
The American Journal of Gastroenterology; Kwo, P. et. al.

Jun 30th, 2017 - Clinicians are required to assess abnormal liver chemistries on a daily basis. The most common liver chemistries ordered are serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase and bilirubin. These tests sh...

Screening of infants for hyperbilirubinemia to prevent chronic bilirubin encephalopathy...
https://doi.org/10.1542/peds.2009-0128
Pediatrics

Sep 29th, 2009 - Recommendation on screening newborn infants, based on a recent supplemental review of a 2003 Agency for Healthcare Research and Quality evidence report on the effectiveness of various screening strategies for preventing the development of chronic ...

ACG Clinical Guideline: Evaluation of Abnormal Liver Chemistries.
https://doi.org/10.1038/ajg.2016.517
The American Journal of Gastroenterology; Kwo PY, Cohen SM et. al.

Dec 20th, 2016 - Clinicians are required to assess abnormal liver chemistries on a daily basis. The most common liver chemistries ordered are serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase and bilirubin. These tests sh...

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for UGT1A1 and Ata...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4785051
Clinical Pharmacology and Therapeutics; Gammal RS, Court MH et. al.

Sep 29th, 2015 - The antiretroviral protease inhibitor atazanavir inhibits hepatic uridine diphosphate glucuronosyltransferase (UGT) 1A1, thereby preventing the glucuronidation and elimination of bilirubin. Resultant indirect hyperbilirubinemia with jaundice can c...

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Drugs  2 results see all →

Clinicaltrials.gov  6,597 results

Liver Structure and Function - Hepatic and Biliary Disorders - Merck Manuals Professional Edition
https://www.merckmanuals.com/professional/hepatic-and-biliary-disorders/approach-to-the-patient-with-liver-disease/liver-structure-and-function

Jan 1st, 2018 - The liver is the most metabolically complex organ. Hepatocytes (liver parenchymal cells) perform the liver’s metabolic functions: Formation and excretion of bile during bilirubin metabolism (see Overview of Bilirubin Metabolism) Regulation of ...

ACG Clinical Guideline: Evaluation of Abnormal Liver Chemistries
https://journals.lww.com/ajg/pages/articleviewer.aspx?year=2017&issue=01000&article=00013&type=Fulltext
The American Journal of Gastroenterology; Kwo, P. et. al.

Jun 30th, 2017 - Clinicians are required to assess abnormal liver chemistries on a daily basis. The most common liver chemistries ordered are serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase and bilirubin. These tests sh...

Risk of Autism Associated With Hyperbilirubinemia and Phototherapy.
https://doi.org/10.1542/peds.2016-1813
Pediatrics Wu YW, Kuzniewicz MW et. al.

Sep 27th, 2016 - Whether neonatal hyperbilirubinemia and/or phototherapy increase the risk of autism spectrum disorder (ASD) is unclear. We sought to quantify the risk of ASD associated with elevated total serum bilirubin (TSB) levels and with phototherapy. In a r...

Utility of Decision Rules for Transcutaneous Bilirubin Measurements.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845868
Pediatrics Taylor JA, Burgos AE et. al.

May 31st, 2016 - Transcutaneous bilirubin (TcB) meters are widely used for screening newborns for jaundice, with a total serum bilirubin (TSB) measurement indicated when the TcB value is classified as "positive" by using a decision rule. The goal of our study was ...

Association Between Laboratory Calibration of a Serum Bilirubin Assay, Neonatal Bilirub...
https://doi.org/10.1001/jamapediatrics.2015.4944
JAMA Pediatrics; Kuzniewicz MW, Greene DN et. al.

Apr 11th, 2016 - The American Academy of Pediatrics treatment recommendations for neonatal jaundice are based on age-specific total serum bilirubin (TSB) levels. In May 2012, Ortho Clinical Diagnostics adjusted the calibrator values for Vitros Chemistry Products B...

see more →

News  275 results

Liver Structure and Function - Hepatic and Biliary Disorders - Merck Manuals Professional Edition
https://www.merckmanuals.com/professional/hepatic-and-biliary-disorders/approach-to-the-patient-with-liver-disease/liver-structure-and-function

Jan 1st, 2018 - The liver is the most metabolically complex organ. Hepatocytes (liver parenchymal cells) perform the liver’s metabolic functions: Formation and excretion of bile during bilirubin metabolism (see Overview of Bilirubin Metabolism) Regulation of ...

ACG Clinical Guideline: Evaluation of Abnormal Liver Chemistries
https://journals.lww.com/ajg/pages/articleviewer.aspx?year=2017&issue=01000&article=00013&type=Fulltext
The American Journal of Gastroenterology; Kwo, P. et. al.

Jun 30th, 2017 - Clinicians are required to assess abnormal liver chemistries on a daily basis. The most common liver chemistries ordered are serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase and bilirubin. These tests sh...

AASLD: Liver transplants should proceed despite COVID-19
https://www.mdedge.com/surgery/article/220026/coronavirus-updates/aasld-liver-transplants-should-proceed-despite-covid-19?channel=63993
M. Alexander Otto

Apr 1st, 2020 - In liver transplant recipients or patients with autoimmune hepatitis on immunosuppressive therapy, acute cellular rejection or disease flare should not be presumed in the face of active coronavirus disease 2019 (COVID-19), according to the America.

Two-Step Screening Strategy for Biliary Atresia in Newborns Shows Promise
https://www.medscape.com/viewarticle/927446

Mar 24th, 2020 - NEW YORK (Reuters Health) - Newborn screening for biliary atresia using direct or conjugated bilirubin measurements has a high diagnostic yield, detecting all known infants with the rare liver disorder in a large cross-sectional study of infants b...

Low Bilirubin, Normal Alkaline Phosphatase Tied to Better Outcomes of Biliary Cholangitis
https://www.medscape.com/viewarticle/926866

Mar 17th, 2020 - NEW YORK (Reuters Health) - Treatment targets for improved survival in primary biliary cholangitis should include low-normal bilirubin and normal alkaline phosphatase levels, a new study suggests. Various surrogate markers have been proposed to pr...

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Patient Education  27 results see all →