ALLMedicine™ Alanine Aminotransferase Center

Aug 5th, 2022 - Pre-eclampsia can be described as new-onset hypertension (blood pressure ≥140/90 mmHg) together with proteinuria (24-hr urinary protein ≥ 0.3 g) or any indication of end-organ damage after 20 weeks of gestation. Liver and kidney dysfunction, throm...

Aug 5th, 2022 - Prevention of dementia is a public health priority, and the identification of potential biomarkers may provide benefits for early detection and prevention. This study investigates the association of common serum laboratory tests with the risk of i...

Aug 4th, 2022 - PRIMARY OBJECTIVES: I. To estimate the maximum tolerated dose (MTD) and/or recommended phase 2 dose (RP2D) of BAY 1895344 (elimusertib) administered as an oral tablet, twice per day for 3 days on and 4 days off to patients < 18 years of age with r...

Aug 3rd, 2022 - Inclusion criteria: Patients with stage IV breast cancer with metastases demonstrated by appropriate imaging techniques Histologically or cytologically confirmed tumor Age of 18 years or more Eastern Cooperative Oncology Group (ECOG) performance s...

Aug 3rd, 2022 - T cell immunoglobulin domain, and mucin domain-3 (Tim-3) is associated with immunosuppression, immune tolerance, and rejection after organ transplantation, but there are no reports of rejection after human liver transplantation. This study aimed t...

Dec 21st, 2016 - Clinicians are required to assess abnormal liver chemistries on a daily basis. The most common liver chemistries ordered are serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase and bilirubin. These tests sh...

Oct 5th, 2010 - Chronic hepatitis B virus (HBV) infection in children presents a therapeutic challenge for the practitioner. Decisions regarding selection of patients who may benefit from treatment, appropriate timing of treatment, and the choice of antiviral the...

Aug 4th, 2022 - PRIMARY OBJECTIVES: I. To estimate the maximum tolerated dose (MTD) and/or recommended phase 2 dose (RP2D) of BAY 1895344 (elimusertib) administered as an oral tablet, twice per day for 3 days on and 4 days off to patients < 18 years of age with r...

Aug 3rd, 2022 - Inclusion criteria: Patients with stage IV breast cancer with metastases demonstrated by appropriate imaging techniques Histologically or cytologically confirmed tumor Age of 18 years or more Eastern Cooperative Oncology Group (ECOG) performance s...

Aug 3rd, 2022 - PRIMARY OBJECTIVE: I. To compare undetectable measurable residual disease (MRD) event-free survival (EFS) rate of the experimental arm (A) to standard arm (B) with EFS defined as time from randomization to occurrence of an event. SECONDARY OBJECTI...

Aug 2nd, 2022 - Day 1 The following will be collected on day 1 of study inclusion: i. Collection of 20ml of blood (preferably from indwelling arterial or central venous catheters which are required for routine medical care of the patient). This sample will be ana...

Aug 2nd, 2022 - This is a multi-center trial. INVESTIGATIONAL TREATMENT: Eligible patients will be receive atezolizumab 1200 mg IV flat dose plus bevacizumab 15 mg/kg IV every 21 days 21 days equals 1 cycle of therapy and patients will be eligible to continue tre...

Jul 29th, 2022 - A novel liquid biopsy test, which uses two circulating proteins, appears to be effective for diagnosing two major liver conditions, according to a new study published in Gut. The test could allow clinicians to determine the staging of both liver f...

Jul 20th, 2022 - A 55-YEAR-OLD MAN with hypertension and untreated hepatitis C virus (HCV) was referred to the Dermatology Clinic after reporting a 2-year history of photosensitivity and intermittent episodes of blistering and scars on the dorsal side of his hands.

Jun 30th, 2022 - NEW YORK (Reuters Health) - Severe COVID-19 increases the risk for cholestasis and secondary sclerosing cholangitis (SSC) in patients with chronic liver disease (CLD), researchers say. Among 65 patients with preexisting CLD who were hospitalized f...

Jun 29th, 2022 - NEW YORK (Reuters Health) - Coexistence of hepatitis B surface antigen (HBsAg) and antibody against HBsAg (anti-HBs) in patients with chronic hepatitis B, while unusual, is associated with more advanced liver disease, such as severe fibrosis and c...

May 6th, 2022 - The Centers for Disease Control and Prevention (CDC) is now investigating 109 cases of unexplained pediatric hepatitis cases in 25 US states and territories, the public health agency said today. Nearly all the children (90%) required hospitalizati...