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About 10,253 results

ALLMedicine™ Alanine Aminotransferase Center

Research & Reviews  3,829 results

Genome-wide association study of liver enzyme elevation in rheumatoid arthritis patient...
https://doi.org/10.2217/pgs-2021-0064
Pharmacogenomics Sundbaum JK, Baecklund E et. al.

Sep 16th, 2021 - Aim: To identify novel genetic variants predisposing to elevation of Alanine aminotransferase (ALT) in rheumatoid arthritis (RA) patients after initiation of methotrexate (MTX) treatment. Patients & methods: We performed genome-wide association st...

Reactivation of hepatitis B virus infection in patients with rheumatoid arthritis recei...
https://doi.org/10.1111/1756-185X.14217
International Journal of Rheumatic Diseases; Wang ST, Tseng CW et. al.

Sep 11th, 2021 - The aim of this study was to investigate hepatitis B virus (HBV) reactivation in patients with rheumatoid arthritis (RA) receiving tofacitinib. This was a retrospective study performed in a regional teaching hospital in southern Taiwan. During Jan...

Acute Liver Injury in Patients Hospitalized with COVID-19.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8419385
Digestive Diseases and Sciences; Sobotka LA, Esteban J et. al.

Sep 7th, 2021 - The prevalence and significance of acute liver injury in patients with COVID-19 are poorly characterized. Patients with confirmed COVID-19 who were hospitalized in geographically diverse medical centers in North America were included. Demographics...

Crimean-Congo haemorrhagic fever-induced liver injury: A systematic review and meta-ana...
https://doi.org/10.1111/ijcp.14775
International Journal of Clinical Practice; Rathore SS, Manju AH et. al.

Sep 5th, 2021 - Crimean-Congo haemorrhagic fever (CCHF) is a fatal acute tick-borne viral infection and substantial emerging global public health threat. This illness has a high case fatality rate of up to 40%. The liver is one of the important target organs of t...

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Guidelines  2 results

ACG Clinical Guideline: Evaluation of Abnormal Liver Chemistries.
https://doi.org/10.1038/ajg.2016.517
The American Journal of Gastroenterology; Kwo PY, Cohen SM et. al.

Dec 21st, 2016 - Clinicians are required to assess abnormal liver chemistries on a daily basis. The most common liver chemistries ordered are serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase and bilirubin. These tests sh...

Treatment of children with chronic hepatitis B virus infection in the United States: pa...
https://doi.org/10.1002/hep.23934
Hepatology (Baltimore, Md.); Jonas MM, Block JM et. al.

Oct 5th, 2010 - Chronic hepatitis B virus (HBV) infection in children presents a therapeutic challenge for the practitioner. Decisions regarding selection of patients who may benefit from treatment, appropriate timing of treatment, and the choice of antiviral the...

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Drugs  37 results see all →

Clinicaltrials.gov  4 results

Stopping TDF Treatment After Long Term Virologic Suppression in HBeAg-negative CHB
https://clinicaltrials.gov/ct2/show/NCT01320943

Aug 29th, 2017 - The primary objective of this study is to evaluate hepatitis B surface antigen (HBsAg) loss and seroconversion in participants who stop tenofovir disoproxil fumarate (TDF) (Stop TDF arm) compared to participants who continue TDF (Continue TDF arm)...

Efficacy of a Structured Weight Loss Program in Overweight Women With a History of Recurrent Pregnancy Loss
https://clinicaltrials.gov/ct2/show/NCT01325805

Nov 25th, 2016 - The purpose of this study is to investigate the impact of a structured weight loss program versus traditional weight-loss counseling on pregnancy outcomes in women with recurrent pregnancy loss. The study protocol is as follows: Patients will be n...

CGRP, Estrogen, Cortisol, VIP, α-Amylase, PGE2, PGI2 and ß-Endorphin Levels in Menstrual Migraine Before and After Treximet
https://clinicaltrials.gov/ct2/show/NCT01329562

Apr 9th, 2014 - This double-blind multi-site study will be conducted to enroll 40 evaluable participants. All subjects will be medically stable at enrollment and be on a stabilized dosage of daily medications. At Visit 1 (Baseline) following Informed Consent, a p...

Efficacy, Safety and Tolerability of Telbivudine in HBeAg Positive Chronic Hepatitis B Pregnant Women With Elevated Alanine Aminotransferase Levels
https://clinicaltrials.gov/ct2/show/NCT01337791

Apr 19th, 2011 - Telbivudine reduces DNA and normalizes alanine aminotransferase levels (ALT) in chronic hepatitis B patients with few adverse effects, but its use during pregnancy has not been explored. In this open-label, prospective study from the second trimes...

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News  229 results

Adverse Events in HER2-Positive Metastatic Breast Cancer Treatment
https://www.onclive.com/view/adverse-events-in-her2-positive-metastatic-breast-cancer-treatment

Jul 15th, 2021 - Sara A. Hurvitz, MD: Longer-term safety data were also presented at ASCO [the American Society of Clinical Oncology annual meeting] for the HER2CLIMB trial. The safety data were reassuring; there were no new safety events or signals that were pick...

FDA Grants Regular Approval to Enfortumab Vedotin, Expands Indication for Locally Advanced or Metastatic Urothelial Cancer
https://www.onclive.com/view/fda-grants-regular-approval-to-enfortumab-vedotin-expands-indication-for-locally-advanced-or-metastatic-urothelial-cancer

Jul 9th, 2021 - The FDA has granted a regular approval to enfortumab vedotin-ejfv (Padcev) and has expanded the agent's indication to include adult patients with locally advanced or metastatic urothelial cancer who are ineligible for cisplatin-containing chemothe...

Zandelisib/Zanubrutinib Yields Promising Responses in R/R CLL, and B-cell Malignancies
https://www.onclive.com/view/zandelisib-zanubrutinib-yields-promising-responses-in-r-r-cll-and-b-cell-malignancies

Jun 11th, 2021 - A 60 mg dose of zandelisib (ME-401) administered on an intermittent schedule from cycle 1 plus 80 mg of zanubrutinib (Brukinsa) twice daily yielded promising response rates in patients with relapsed/refractory B-cell malignancies and chronic lymph...

Pembrolizumab Plus Gemcitabine/Hypofractionated Radiotherapy Demonstrates Promising Efficacy in Muscle-Invasive Bladder Cancer
https://www.onclive.com/view/pembrolizumab-plus-gemcitabine-hypofractionated-radiotherapy-demonstrates-promising-efficacy-in-muscle-invasive-bladder-cancer

Jun 7th, 2021 - Pembrolizumab (Keytruda) in combination with gemcitabine and concurrent hypofractionated radiotherapy (RT) appears to be a promising and efficacious, bladder-sparing regimen for patients with muscle-invasive bladder cancer (MIBC), according to fin...

Neoadjuvant Pertuzumab Plus Trastuzumab/Nab-Paclitaxel Achieves 64% pCR With Less Toxicity in HER2+ Breast Cancer
https://www.onclive.com/view/neoadjuvant-pertuzumab-plus-trastuzumab-nab-paclitaxel-achieves-64-pcr-with-less-toxicity-in-her2-breast-cancer

Jun 6th, 2021 - The anthracycline-free regimen of pertuzumab (Perjeta) plus trastuzumab (Herceptin), and nab-paclitaxel (Abraxane) used as neoadjuvant therapy (NT) in patients with HER2-positive locally advanced breast cancer induced a pathologic complete respons...

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