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About 16,488 results

ALLMedicine™ Alanine Aminotransferase Center

Research & Reviews  5,220 results

The efficacy and safety of caplacizumab in Japanese patients with immune-mediated throm...
https://doi.org/10.1007/s12185-022-03495-6
International Journal of Hematology; Miyakawa Y, Imada K et. al.

Nov 26th, 2022 - Caplacizumab is an anti-von Willebrand factor humanized single-variable-domain immunoglobulin fragment whose efficacy and safety in immune-mediated thrombotic thrombocytopenia purpura (iTTP) have been demonstrated in international studies. This pr...

FABP5 Deficiency Impaired Macrophage Inflammation by Regulating AMPK/NF-κB Signaling Pa...
https://doi.org/10.4049/jimmunol.2200182
Journal of Immunology (Baltimore, Md. : 1950); Hou Y, Wei D et. al.

Nov 26th, 2022 - Fatty acid binding protein 5 (FABP5) is mainly involved in the uptake, transport, and metabolism of fatty acid in the cytoplasm, and its role in immune cells has been recognized in recent years. However, the role of FABP5 in macrophage inflammatio...

The role of serum nesfatin-1 in a rat model of acute pancreatitis.
https://doi.org/10.17219/acem/156141
Advances in Clinical and Experimental Medicine : Official... Ferlengez AG, Tatar C et. al.

Nov 26th, 2022 - Acute pancreatitis (AP) is a disease that can still be fatal despite rapid advances in medicine. The relationship between serum nesfatin-1 levels and AP is still to be fully resolved. To investigate the utility of serum nesfatin-1 levels in the di...

ABO rs657152 and Blood Groups Are as Predictor Factors of COVID-19 Mortality in the Ira...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9678483
Disease Markers; Mirzaei Gheinari F, Sakhaee F et. al.

Nov 25th, 2022 - Several studies have discovered a relationship between specific blood types, genetic variations of the ABO gene, and coronavirus disease 2019 (COVID-19). Therefore, the aim of this study was to evaluate the association between ABO rs657152 polymor...

Association between serum homocysteine and sarcopenia among hospitalized older Chinese ...
https://doi.org/10.1186/s12877-022-03632-0
BMC Geriatrics; Lu B, Shen L et. al.

Nov 25th, 2022 - Hyperhomocysteinemia (HHcy) is considered to increase the risk of sarcopenia (S) and remains controversial. In this study, we aimed to investigate the prevalence of S among older Chinese adults and explore whether homocysteine (Hcy) was independen...

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Guidelines  2 results

ACG Clinical Guideline: Evaluation of Abnormal Liver Chemistries.
https://doi.org/10.1038/ajg.2016.517
The American Journal of Gastroenterology; Kwo PY, Cohen SM et. al.

Dec 21st, 2016 - Clinicians are required to assess abnormal liver chemistries on a daily basis. The most common liver chemistries ordered are serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase and bilirubin. These tests sh...

Treatment of children with chronic hepatitis B virus infection in the United States: pa...
https://doi.org/10.1002/hep.23934
Hepatology (Baltimore, Md.); Jonas MM, Block JM et. al.

Oct 5th, 2010 - Chronic hepatitis B virus (HBV) infection in children presents a therapeutic challenge for the practitioner. Decisions regarding selection of patients who may benefit from treatment, appropriate timing of treatment, and the choice of antiviral the...

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Drugs  69 results see all →

Clinicaltrials.gov  346 results

Study of Baricitinib, a JAK1/2 Inhibitor, in Chronic Graft-Versus-Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation
https://clinicaltrials.gov/ct2/show/NCT02759731

Oct 12th, 2022 - Background: Chronic graft-versus-host disease (cGVHD) is the leading cause of non-relapse morbidity and mortality in persons after allogeneic hematopoietic stem cell transplantation (SCT). Approximately 50% of patients with cGVHD have disease refr...

Pembrolizumab + Imprime PGG for Metastatic Non-small Cell Lung Cancer After Progression on First-Line Therapy: Big Ten Cancer Research Consortium BTCRC-LUN15-017
https://clinicaltrials.gov/ct2/show/NCT03003468

Oct 7th, 2022 - OUTLINE: This is a multi-center study. The phase Ib dose escalation will evaluate the combination of pembrolizumab and Imprime PGG for subjects with metastatic non-small cell lung cancer (NSCLC) after progression on first-line platinum-based chemo...

Vitamin E Dosing Study
https://clinicaltrials.gov/ct2/show/NCT04801849

Oct 7th, 2022 - Adults age 18 years or older will be enrolled for 48 weeks and treated with 200 international units (IU), 400 IU, or 800 IU of Vitamin E or matching placebo for 24 weeks. The primary objective of the study is to determine the minimum effective dos...

Skeletal Muscle Biomarkers in People With Fragile Sarcolemmal Muscular Dystrophy
https://clinicaltrials.gov/ct2/show/NCT01851447

Oct 3rd, 2022 - Objectives: the aim of this protocol is to identify biomarker and clinical correlates of changes in the barrier function of skeletal muscle membrane (i.e. cell membrane permeability) before and after routine motor function testing in patients with...

The Markers and Paracetamol Poisoning Study 2
https://clinicaltrials.gov/ct2/show/NCT03497104

Sep 28th, 2022 - Paracetamol overdose is one of the most common medical emergencies. Annually in the UK, 100,000 people seek medical attention and 50,000 need hospital admission. Treatment is with the antidote acetylcysteine (NAC), which is effective but takes 21 ...

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News  958 results

Cilta-cel Induces Strong Response in Chinese Patients With Relapsed/Refractory Multiple Myeloma
https://www.onclive.com/view/cilta-cel-induces-strong-response-in-chinese-patients-with-relapsed-refractory-multiple-myeloma

Nov 21st, 2022 - Ciltacabtagene autoleucel (cilta-cel; Carvykti) produced early, deep, and durable responses in patients with relapsed/refractory multiple myeloma (RRMM) treated at 8 sites in China.1 Investigators said the results from the pivotal phase 2 CARTIFAN...

FDA Requests Restriction of Second-line Maintenance Niraparib Indication in Ovarian Cancer
https://www.onclive.com/view/fda-requests-restriction-of-second-line-maintenance-niraparib-indication-in-ovarian-cancer

Nov 17th, 2022 - At the request of the FDA, GlaxoSmithKline (GSK) plc will restrict the second-line maintenance indication for niraparib (Zejula) to only the population of patients with recurrent ovarian cancer whose tumors harbor deleterious or suspected deleteri...

FDA Approves Mirvetuximab Soravtansine-gynx for FRα+ Platinum-resistant Ovarian Cancer
https://www.onclive.com/view/fda-approves-mirvetuximab-soravtansine-gynx-for-fr-platinum-resistant-ovarian-cancer

Nov 17th, 2022 - The FDA has granted accelerated approval to mirvetuximab soravtansine-gynx (Elahere) for the treatment of adult patients with folate receptor α (Frα)–positive, platinum-resistant epithelial ovarian, fallopian tube, or primary peritoneal cancer, wh...

IBD and Preterm Birth Risk; Leprosy Bacteria Promote Liver Growth; COVID and IBD
https://www.medpagetoday.com/gastroenterology/generalgastroenterology/101812

Nov 17th, 2022 - Histological inflammation and clinical disease activity in inflammatory bowel disease (IBD) were risk factors for preterm birth, especially in the case of ulcerative colitis. (eClinicalMedicine) Leprosy-causing bacteria (Mycobacterium leprae) prom...

FDA Approves First IHC Companion Diagnostic for Mirvetuximab Soravtansine in Ovarian Cancer
https://www.onclive.com/view/fda-approves-first-ihc-companion-diagnostic-for-mirvetuximab-soravtansine-in-ovarian-cancer

Nov 15th, 2022 - The FDA has approved the VENTANA FOLR1 (FOLR1-2.1) RxDx assay, the first immunohistochemistry (IHC) companion diagnostic test to help identify patients with epithelial ovarian cancer who are eligible for treatment with mirvetuximab soravtansine-gy...

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