ALLMedicine™ Bilirubin Center

Dec 3rd, 2021 - Neonatal jaundice may cause severe neurological damage if poorly evaluated and diagnosed when high bilirubin occurs. The study explored how to effectively integrate high-dimensional genetic features into predicting neonatal jaundice. This study re...

Dec 3rd, 2021 - Intravenous lipid emulsions are commonly used as a part of parenteral nutrition in premature infants. The potential bilirubin-displacing effects of high free fatty acid (FFA) levels during lipid infusions are known. Levels of free bilirubin (FB) p...

Dec 1st, 2021 - To report the safety and effectiveness of laparoscopic intratumoral resection facilitated by coagulation (LIRC) compared with laparoscopic hepatectomy (LH) in treating giant hepatic hemangioma. From 2017 to 2020, 19 consecutive patients with giant...

Dec 1st, 2021 - To evaluate the efficacy and safety of brachytherapy with double-strand 125I seeds and biliary drainage for malignant obstructive jaundice. 42 patients with obstructive jaundice because of extrahepatic cholangiocarcinoma were enrolled. 22 patients...

Nov 30th, 2021 - Heme oxygenase‑1 (HO‑1) is an inducible cytoprotective enzyme that degrades heme into free iron, carbon monoxide and biliverdin, which is then rapidly converted into bilirubin. These degradation products serve an important role in the regulation o...

Mar 30th, 2018 - Primary biliary cholangitis (formerly known as primary biliary cirrhosis, PBC) is an autoimmune liver disease in which a cycle of immune mediated biliary epithelial cell injury, cholestasis and progressive fibrosis can culminate over time in an en...

Dec 21st, 2016 - Clinicians are required to assess abnormal liver chemistries on a daily basis. The most common liver chemistries ordered are serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase and bilirubin. These tests sh...

Jul 19th, 2016 - Cholestatic jaundice in infancy affects approximately 1 in every 2500 term infants and is infrequently recognized by primary providers in the setting of physiologic jaundice. Cholestatic jaundice is always pathologic and indicates hepatobiliary dy...

Sep 30th, 2015 - The antiretroviral protease inhibitor atazanavir inhibits hepatic uridine diphosphate glucuronosyltransferase (UGT) 1A1, thereby preventing the glucuronidation and elimination of bilirubin. Resultant indirect hyperbilirubinemia with jaundice can c...

Dec 14th, 2011 - Prevention of acute bilirubin encephalopathy and kernicterus in newborns: position statement #3049.|2011| ,|blood,complications,diagnosis,prevention & control,etiology,prevention & control,methods,

Nov 23rd, 2021 - To determine the effect of low dose azacitidine therapy on tumor infiltrating lymphocytes (TILs) in primary tumors from patients with high-risk early stage breast cancer, paired t-tests will be first used to compare TIL count in pre- and post-trea...

Nov 19th, 2021 - Patients and Methods This prospective,cross over study will be conducted after obtaining approval from the Institutional Review Board (IRB) of faculty of medicine Mansoura University. A written informed consent will be obtained from all participan...

Nov 19th, 2021 - This is a cross-sectional, pilot study to characterize the response of neonatal premature skin to DRS when excited with a white light source, and provide a baseline of how the collected spectra change with the maturation of the epidermal layer in ...

Nov 16th, 2021 - Neonatal jaundice is common and mostly transient without need for intervention. To identify infants at risk of bilirubin toxicity, bilirubin is measured several times after birth and before discharge home. As the peak bilirubin concentrations are ...

Nov 16th, 2021 - Background: About 30,000 men will die from prostate cancer in the US in 2018. The majority of these men originally presented with localized cancer. Treatment options for patients with high risk, localized disease typically involve radical prostate...

Oct 25th, 2021 - This article was updated Nov. 5, 2021.

Oct 20th, 2021 - Key clinical point: Cabozatinib significantly improved overall survival and progression-free survival in HCC patients with ALBI grades 1 and 2 compared with placebo. Major finding: Median overall survival in HCC patients with ALBI grade 1 was 17.

Oct 7th, 2021 - NEW YORK (Reuters Health) - In patients taking immune checkpoint inhibitors (ICIs) who developed moderate-to-severe liver injury, a biopsy delayed steroid initiation and was not associated with more rapid hepatitis resolution of hepatitis, an obse...

Oct 6th, 2021 - Naval Daver, MD The combination of nivolumab (Opdivo) and azacitidine demonstrated favorable responses and overall survival (OS) in patients with relapsed/refractory acute myeloid leukemia (AML), according to preliminary findings of a phase II st...

Oct 6th, 2021 - We recently traveled to Miami, Florida, for a State of the Science Summit™ on Gastrointestinal Malignancies. Targeted therapy has become an important fixture in oncogene-driven cancers, particularly in BRAF V600E-mutant metastatic colorectal cance...