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About 13,473 results

ALLMedicine™ Bilirubin Center

Research & Reviews  4,603 results

Preliminary application of brachytherapy with double-strand 125I seeds and biliary drai...
https://doi.org/10.1007/s00464-021-08848-6 10.1007/s00464-012-2773-7 10.1097/MD.0000000000015131 10.1007/s00464-016-5008-5 10.1186/s12957-016-0883-8 10.1016/j.brachy.2018.04.001 10.4103/0973-1075.191746 10.1016/j.jss.2014.07.060 10.5946/ce.2013.46.5.515 10.1016/j.jvir.2016.11.038 10.5009/gnl.2013.7.4.480 10.1016/j.gie.2008.08.033
Surgical Endoscopy; Li ZM, Jiao DC et. al.

Dec 1st, 2021 - To evaluate the efficacy and safety of brachytherapy with double-strand 125I seeds and biliary drainage for malignant obstructive jaundice. 42 patients with obstructive jaundice because of extrahepatic cholangiocarcinoma were enrolled. 22 patients...

Association between HO‑1 gene promoter polymorphisms and diseases (Review).
https://doi.org/10.3892/mmr.2021.12545
Molecular Medicine Reports; Ma LL, Sun L et. al.

Nov 30th, 2021 - Heme oxygenase‑1 (HO‑1) is an inducible cytoprotective enzyme that degrades heme into free iron, carbon monoxide and biliverdin, which is then rapidly converted into bilirubin. These degradation products serve an important role in the regulation o...

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Guidelines  7 results

The British Society of Gastroenterology/UK-PBC primary biliary cholangitis treatment an...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109281
Gut Hirschfield GM, Dyson JK et. al.

Mar 30th, 2018 - Primary biliary cholangitis (formerly known as primary biliary cirrhosis, PBC) is an autoimmune liver disease in which a cycle of immune mediated biliary epithelial cell injury, cholestasis and progressive fibrosis can culminate over time in an en...

ACG Clinical Guideline: Evaluation of Abnormal Liver Chemistries.
https://doi.org/10.1038/ajg.2016.517
The American Journal of Gastroenterology; Kwo PY, Cohen SM et. al.

Dec 21st, 2016 - Clinicians are required to assess abnormal liver chemistries on a daily basis. The most common liver chemistries ordered are serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase and bilirubin. These tests sh...

Guideline for the Evaluation of Cholestatic Jaundice in Infants: Joint Recommendations ...
https://doi.org/10.1097/MPG.0000000000001334
Journal of Pediatric Gastroenterology and Nutrition; Fawaz R, Baumann U et. al.

Jul 19th, 2016 - Cholestatic jaundice in infancy affects approximately 1 in every 2500 term infants and is infrequently recognized by primary providers in the setting of physiologic jaundice. Cholestatic jaundice is always pathologic and indicates hepatobiliary dy...

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for UGT1A1 and Ata...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4785051
Clinical Pharmacology and Therapeutics; Gammal RS, Court MH et. al.

Sep 30th, 2015 - The antiretroviral protease inhibitor atazanavir inhibits hepatic uridine diphosphate glucuronosyltransferase (UGT) 1A1, thereby preventing the glucuronidation and elimination of bilirubin. Resultant indirect hyperbilirubinemia with jaundice can c...

Prevention of acute bilirubin encephalopathy and kernicterus in newborns: position stat...
https://doi.org/10.1097/ANC.0b013e31822efd64
Advances in Neonatal Care : Official Journal of the Natio...

Dec 14th, 2011 - Prevention of acute bilirubin encephalopathy and kernicterus in newborns: position statement #3049.|2011| ,|blood,complications,diagnosis,prevention & control,etiology,prevention & control,methods,

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Drugs  102 results see all →

Clinicaltrials.gov  283 results

BRE-04: Window of Opportunity Trial of Preoperative Low Dose Azacitidine in High-Risk Early Stage Breast Cancer
https://clinicaltrials.gov/ct2/show/NCT04891068

Nov 23rd, 2021 - To determine the effect of low dose azacitidine therapy on tumor infiltrating lymphocytes (TILs) in primary tumors from patients with high-risk early stage breast cancer, paired t-tests will be first used to compare TIL count in pre- and post-trea...

Pressure Support Ventilation Versus Continuous Positive Air Way Pressure (CPAP) Using I Gelin Adult Patients,
https://clinicaltrials.gov/ct2/show/NCT05116839

Nov 19th, 2021 - Patients and Methods This prospective,cross over study will be conducted after obtaining approval from the Institutional Review Board (IRB) of faculty of medicine Mansoura University. A written informed consent will be obtained from all participan...

Characterization of Pre-Term Neonatal Skin
https://clinicaltrials.gov/ct2/show/NCT05127044

Nov 19th, 2021 - This is a cross-sectional, pilot study to characterize the response of neonatal premature skin to DRS when excited with a white light source, and provide a baseline of how the collected spectra change with the maturation of the epidermal layer in ...

Assessment of Neonatal Hyperbilirubinemia by NeoprediX B.1 Algorithm
https://clinicaltrials.gov/ct2/show/NCT05121311

Nov 16th, 2021 - Neonatal jaundice is common and mostly transient without need for intervention. To identify infants at risk of bilirubin toxicity, bilirubin is measured several times after birth and before discharge home. As the peak bilirubin concentrations are ...

Prostate Specific Membrane Antigen (PMSA)-Based PET Imaging of High Risk Prostate Cancer
https://clinicaltrials.gov/ct2/show/NCT03976843

Nov 16th, 2021 - Background: About 30,000 men will die from prostate cancer in the US in 2018. The majority of these men originally presented with localized cancer. Treatment options for patients with high risk, localized disease typically involve radical prostate...

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News  386 results

Cabozantinib promotes survival in HCC for both ALBI subgroups
https://www.mdedge.com/fedprac/article/247632/hepatocellular-carcinoma/cabozantinib-promotes-survival-hcc-both-albi

Oct 20th, 2021 - Key clinical point: Cabozatinib significantly improved overall survival and progression-free survival in HCC patients with ALBI grades 1 and 2 compared with placebo. Major finding: Median overall survival in HCC patients with ALBI grade 1 was 17.

Biopsy May Not Be Needed to Treat Immune Checkpoint Inhibitor-Associated Hepatitis
https://www.medscape.com/viewarticle/960399

Oct 7th, 2021 - NEW YORK (Reuters Health) - In patients taking immune checkpoint inhibitors (ICIs) who developed moderate-to-severe liver injury, a biopsy delayed steroid initiation and was not associated with more rapid hepatitis resolution of hepatitis, an obse...

Nivolumab Combo Shows Early Activity in Relapsed/Refractory AML
https://www.onclive.com/view/nivolumab-combo-shows-early-activity-in-relapsedrefractory-aml

Oct 6th, 2021 - Naval Daver, MD The combination of nivolumab (Opdivo) and azacitidine demonstrated favorable responses and overall survival (OS) in patients with relapsed/refractory acute myeloid leukemia (AML), according to preliminary findings of a phase II st...

FLASCO Faculty Flesh Out Case Studies in GI Cancers
https://www.onclive.com/view/flasco-faculty-flesh-out-case-studies-in-gi-cancers

Oct 6th, 2021 - We recently traveled to Miami, Florida, for a State of the Science Summit™ on Gastrointestinal Malignancies. Targeted therapy has become an important fixture in oncogene-driven cancers, particularly in BRAF V600E-mutant metastatic colorectal cance...

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Patient Education  8 results see all →