ALLMedicine™ Activated Clotting Time Center

Jul 2nd, 2021 - Periprocedural pulmonary vein isolation (PVI) anticoagulation requires balancing between bleeding and thromboembolic risk. Intraprocedural anticoagulation is monitored by activated clotting time (ACT) with target value >300 s, and there are no gui...

Jun 17th, 2021 - Coagulation factor XII (FXII) is a plasma serine protease that belongs to the contact activation complex responsible for initiating the intrinsic coagulation pathway. FXII deficiency is a rare congenital disorder that is not associated with an inc...

Jun 12th, 2021 - In coronavirus disease 2019 (COVID-19) patients with acute respiratory distress syndrome refractory to optimal conventional management, we should consider the indication for veno-venous extracorporeal membrane oxygenation (V-V ECMO). Growing evide...

Jun 11th, 2021 - Anticoagulation monitoring practices vary during extracorporeal membrane oxygenation (ECMO). The Extracorporeal Life Support Organization describes that a multimodal approach is needed to overcome assay limitations and minimize complications. Comp...

Jun 2nd, 2021 - Doppler microembolic signals (MES) occur during atrial fibrillation ablation despite of permanent flushed transseptal sheaths, frequent controls of periprocedural coagulation status and the use of irrigated ablation catheters PURPOSE: To investiga...

Dec 16th, 2019 - Cardiopulmonary bypass (CPB) allows cardiac surgery to be performed on a motionless, bloodless heart while maintaining circulation to the rest of the body. Anticoagulation with heparin prevents the body's clotting system from being activated when ...

Mar 12th, 2019 - This is a pilot study to examine the efficacy and safety of an extracorporeal circuit to remove carbon dioxide (CO2) from the blood in patients with an acute exacerbation of COPD resulting in acute or acute on chronic respiratory failure. The extr...

Sep 24th, 2018 - One hour before the surgery, patients are premedicated with lorazepam (per os, 2.5 mg). Before induction of anesthesia, the NIRS sensors (INVOS 3100, Somanetics, MI, USA) arepositioned on both sides of the forehead. Sensors to detect depth of anes...

Sep 18th, 2018 - Oral anticoagulants are increasingly prescribed and the are not discontinued for invasive cardiac procedures . Additional parenteral anticoagulation is necessary for these procedures (FA ablation and invasive coronary explorations). The unfraction...

May 4th, 2018 - The SONOCLOT Analyzer (S1; Sienco, Inc. Boulder, CO USA, Model DP-2951) is used to routinely perform kaolin-based activated clotting time (kACT) as monitor of heparin therapy in patients undergoing cardiac operations on cardiopulmonary bypass. Apa...

Sep 10th, 2019 - The peculiar heparin behavior started about 6 months ago. Dosing that had been reliable countless times in the cath lab was failing to get the activated clotting time (ACT) to target, forcing extra boluses. "I called my pharmacy and asked them to ...

Sep 10th, 2019 - The peculiar heparin behavior started about 6 months ago. Dosing that had been reliable countless times in the cath lab was failing to get the activated clotting time (ACT) to target, forcing extra boluses. "I called my pharmacy and asked them to ...

Oct 15th, 2015 - SAN FRANCISCO, CA — For patients undergoing transcatheter aortic-valve replacement (TAVR) via the femoral artery, the use of bivalirudin (Angiomax, the Medicines Company) did not significantly reduce the risk of bleeding, nor did it use reduce the...

Aug 4th, 2014 - NEW YORK, NY — "Oral administration, please, but no cumbersome dosing strategies" could have been the tag line of the research community that spent decades looking for a more user-friendly alternative that is at least comparable to warfarin in eff...

Jun 3rd, 2013 - As surgeons use more minimally-invasive approaches to treat peripheral arterial disease, fewer patients need amputations. Also, testing dabigatran's therapeutic level, and the future cost of treating aortic stenosis. Lower Limb Amputations Down Ov...