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About 919 results

ALLMedicine™ Immunofixation Center

Research & Reviews  451 results

Identification Of Paraproteins Via Serum Immunofixation or Serum Immunosubtraction and ...
https://doi.org/10.5858/arpa.2020-0441-OA
Archives of Pathology & Laboratory Medicine; Mrosewski I, Urbank M

Feb 26th, 2021 - In laboratory testing for monoclonal gammopathies, paraproteins are identified via serum immunofixation or serum immunosubtraction and immunoturbidimetric quantitation of serum immunoglobulins is often used. To evaluate methodic differences betwee...

Multiple Myeloma Presenting as Disseminated Osteoblastic Lesions With Intense 18F-FDG U...
https://doi.org/10.1097/RLU.0000000000003542
Clinical Nuclear Medicine; Wang Y, Fan Q et. al.

Feb 25th, 2021 - A 42-year-old woman presented with numbness and weakness in the lower limbs. The radiograph, MRI, and 99mTc-MDP bone scintigraphy revealed multiple bone lesions. The lesions were sclerotic on radiograph. Subsequent 18F-FDG PET/CT showed the lesion...

Cardiac Transthyretin Amyloidosis: A Nuclear Medicine Leading Role. Situation in a Span...
https://doi.org/10.1097/RLU.0000000000003553
Clinical Nuclear Medicine; Roteta Unceta Barrenechea A, Aibar Arregui MA et. al.

Feb 25th, 2021 - Amyloidosis is a heterogeneous group of diseases caused by abnormal extracellular deposition of insoluble proteins and can involve myocardium. One of the causes of myocardial involvement is TTR amyloidosis. Our objective has been to evaluate the s...

Contradictory Phenomenon Between Serum Separator Tube and Plasma Tube: A Case Report.
https://doi.org/10.1093/labmed/lmab003
Laboratory Medicine; Pang L, Xing Y et. al.

Feb 17th, 2021 - Separator gels in blood collection tubes are used to separate serum from clotted whole blood or plasma from cells. Here we present a case of a patient with a contradictory phenomenon between the serum separator tube and the plasma tube. The serum ...

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Guidelines  2 results

Consensus recommendations for standard investigative workup: report of the Internationa...
https://doi.org/10.1182/blood-2010-10-299529
Blood Dimopoulos M, Kyle R et. al.

Feb 4th, 2011 - A panel of members of the 2009 International Myeloma Workshop developed guidelines for standard investigative workup of patients with suspected multiple myeloma. Both serum and urine should be assessed for monoclonal protein. Measurement of monocl...

International Myeloma Working Group guidelines for serum-free light chain analysis in m...
https://doi.org/10.1038/leu.2008.307
Leukemia Dispenzieri A, Kyle R et. al.

Nov 20th, 2008 - The serum immunoglobulin-free light chain (FLC) assay measures levels of free kappa and lambda immunoglobulin light chains. There are three major indications for the FLC assay in the evaluation and management of multiple myeloma and related plasma...

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Clinicaltrials.gov  455 results

Identification Of Paraproteins Via Serum Immunofixation or Serum Immunosubtraction and ...
https://doi.org/10.5858/arpa.2020-0441-OA
Archives of Pathology & Laboratory Medicine; Mrosewski I, Urbank M

Feb 26th, 2021 - In laboratory testing for monoclonal gammopathies, paraproteins are identified via serum immunofixation or serum immunosubtraction and immunoturbidimetric quantitation of serum immunoglobulins is often used. To evaluate methodic differences betwee...

Multiple Myeloma Presenting as Disseminated Osteoblastic Lesions With Intense 18F-FDG U...
https://doi.org/10.1097/RLU.0000000000003542
Clinical Nuclear Medicine; Wang Y, Fan Q et. al.

Feb 25th, 2021 - A 42-year-old woman presented with numbness and weakness in the lower limbs. The radiograph, MRI, and 99mTc-MDP bone scintigraphy revealed multiple bone lesions. The lesions were sclerotic on radiograph. Subsequent 18F-FDG PET/CT showed the lesion...

Cardiac Transthyretin Amyloidosis: A Nuclear Medicine Leading Role. Situation in a Span...
https://doi.org/10.1097/RLU.0000000000003553
Clinical Nuclear Medicine; Roteta Unceta Barrenechea A, Aibar Arregui MA et. al.

Feb 25th, 2021 - Amyloidosis is a heterogeneous group of diseases caused by abnormal extracellular deposition of insoluble proteins and can involve myocardium. One of the causes of myocardial involvement is TTR amyloidosis. Our objective has been to evaluate the s...

Contradictory Phenomenon Between Serum Separator Tube and Plasma Tube: A Case Report.
https://doi.org/10.1093/labmed/lmab003
Laboratory Medicine; Pang L, Xing Y et. al.

Feb 17th, 2021 - Separator gels in blood collection tubes are used to separate serum from clotted whole blood or plasma from cells. Here we present a case of a patient with a contradictory phenomenon between the serum separator tube and the plasma tube. The serum ...

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News  11 results

What is your diagnosis? - June 2019
https://www.mdedge.com/gihepnews/article/202110/what-your-diagnosis-june-2019?channel=27662
Lei Miao, MD, XiangRong Chen, MD et. al.

Jun 3rd, 2019 - Multiple myeloma An abdominal CT scan (Figure D) showed gastric and whole intestinal wall thickening of up to 2 cm. Pathology (Figure E) demonstrated that diffuse plasmacytoid cells, eosinophilic granulocytes, and lymphocytes infiltrated into the.

Fast Five Quiz: Can You Diagnose Waldenström Macroglobulinemia?
https://reference.medscape.com/viewarticle/908942_4

Mar 12th, 2019 - Elevated IgM (confirmed with immunofixation), elevated blood viscosity, and lymphoplasmacytic infiltrate on bone marrow biopsy are diagnostic criteria for WM. In addition, WM cells are often positive for the biomarkers CD19, CD20, CD22, and CD79a....

Waldenstrom Macroglobulinemia Clinical Practice Guidelines (2018)
https://reference.medscape.com/viewarticle/905623

Nov 29th, 2018 - The guidelines on the diagnosis, treatment, and follow-up of Waldenstrom macroglobulinemia were released on October 1, 2018, by the European Society for Medical Oncology (ESMO).[1] Diagnosis Waldenstrom macroglobulinemia (WM) is diagnosed based on...

FDA clears assay for myeloma patients
https://www.mdedge.com/hematology-oncology/article/185159/multiple-myeloma/fda-clears-assay-myeloma-patients
HT Staff

Jan 28th, 2018 - Photo courtesy of Janssen Daratumumab (Darzalex) The US Food and Drug Administration (FDA) has granted 510(k) clearance for Sebia’s Hydrashift 2/4 daratumumab immunofixation assay. This in vitro diagnostic test allows for assessment of response in.

Tests can produce confusing results after HSCT in MM
https://www.mdedge.com/hematology-oncology/article/185506/multiple-myeloma/tests-can-produce-confusing-results-after-hsct-mm
HT Staff

Aug 11th, 2017 - Micrograph showing MM Tests used to assess treatment response in multiple myeloma (MM) may often produce confusing results after patients have undergone hematopoietic stem cell transplant (HSCT), a new study suggests. The tests—serum protein elect.

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