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About 3,021 results

ALLMedicine™ Transferrin Receptor Center

Research & Reviews  1,509 results

A dual-targeting ruthenium nanodrug that inhibits primary tumor growth and lung metasta...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8063440
Journal of Nanobiotechnology; Lu Y, Zhu D et. al.

Apr 24th, 2021 - Many studies have found that ruthenium complexes possess unique biochemical characteristics and inhibit tumor growth or metastasis. Here, we report the novel dual-targeting ruthenium candidate 2b, which has both antitumor and antimetastatic proper...

Transferrin receptor targeting by de novo sheet extension.
https://doi.org/10.1073/pnas.2021569118
Proceedings of the National Academy of Sciences of the Un... Sahtoe DD, Coscia A et. al.

Apr 21st, 2021 - The de novo design of polar protein-protein interactions is challenging because of the thermodynamic cost of stripping water away from the polar groups. Here, we describe a general approach for designing proteins which complement exposed polar bac...

Iron chelators reverse organ damage in type 4B hereditary hemochromatosis: Case reports.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8021318
Medicine Wu LY, Song ZY et. al.

Mar 31st, 2021 - Hereditary hemochromatosis (HH) is a hereditary disorder of iron metabolism. It is classified into 4 main types depending on the underlying genetic mutation: human hemochromatosis protein (HFE) (type 1), hemojuvelin (HJV) (type 2A), HAMP (type 2B)...

Iduronate-2-sulfatase fused with anti-hTfR antibody, pabinafusp alfa, for MPS-II: A pha...
https://doi.org/10.1016/j.ymthe.2021.03.019
Molecular Therapy : the Journal of the American Society O... Giugliani R, Martins AM et. al.

Mar 30th, 2021 - In Hunter syndrome (mucopolysaccharidosis II [MPS-II]), systemic accumulation of glycosaminoglycans (GAGs) due to a deficiency of iduronate-2-sulfatase (IDS), caused by mutations in the IDS gene, leads to multiple somatic manifestations and in pat...

Prevalence and associated factors of iron deficiency in Spanish children aged 1 to 11 y...
https://doi.org/10.1007/s00431-021-04037-8 10.1017/S1368980008002401 10.1542/peds.2010-2576 10.1097/MPG.0000000000000206 10.1097/MPG.0b013e3181adaee0 10.1016/j.anpedi.2011.01.036 10.1007/s00431-020-03597-5 10.1159/000371357 10.1097/MPG.0000000000001015 10.1111/j.1651-2227.2001.tb00787.x 10.1542/peds.2007-0572 10.3945/ajcn.117.155978 10.1016/j.jpeds.2007.09.048 10.1542/peds.2009-2097 10.1007/s12031-019-01276-1 10.1108/NFS-01-2018-0005 10.1111/ijlh.12013 10.1097/MPH.0000000000000639 10.1182/blood.V75.9.1870.1870 10.1016/S0009-8981(03)00005-6 10.3109/10408363.2010.550461 10.1097/MPH.0b013e31802d751a 10.3109/08880018.2015.1138007 10.1002/ajh.22108 10.1007/s00431-018-3257-0 10.1136/bmj.320.7244.1240 10.20960/nh.308 10.1080/10408398.2012.742860 10.1001/jama.277.12.973 10.1179/1607845413Y.0000000124 10.1001/archpedi.162.4.374 10.1542/peds.110.3.545 10.1111/j.1651-2227.2004.tb02983.x 10.1038/sj.ejcn.1601594 10.1097/MPG.0b013e3182a80c42 10.1017/S1368980000000501 10.1097/MPG.0000000000000216 10.1017/S0007114511005952 10.3889/MJMS.1857-5773.2011.0155 10.1001/jama.294.8.924 10.1038/ejcn.2014.70
European Journal of Pediatrics; López-Ruzafa E, Vázquez-López MA et. al.

Mar 24th, 2021 - Iron deficiency (ID) is the most common nutritional deficiency affecting children worldwide. Most traditional laboratory parameters to assess ID can be altered by infections or other inflammatory states, including obesity. The aims of this study w...

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Clinicaltrials.gov  1,511 results

A dual-targeting ruthenium nanodrug that inhibits primary tumor growth and lung metasta...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8063440
Journal of Nanobiotechnology; Lu Y, Zhu D et. al.

Apr 24th, 2021 - Many studies have found that ruthenium complexes possess unique biochemical characteristics and inhibit tumor growth or metastasis. Here, we report the novel dual-targeting ruthenium candidate 2b, which has both antitumor and antimetastatic proper...

Transferrin receptor targeting by de novo sheet extension.
https://doi.org/10.1073/pnas.2021569118
Proceedings of the National Academy of Sciences of the Un... Sahtoe DD, Coscia A et. al.

Apr 21st, 2021 - The de novo design of polar protein-protein interactions is challenging because of the thermodynamic cost of stripping water away from the polar groups. Here, we describe a general approach for designing proteins which complement exposed polar bac...

Iron chelators reverse organ damage in type 4B hereditary hemochromatosis: Case reports.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8021318
Medicine Wu LY, Song ZY et. al.

Mar 31st, 2021 - Hereditary hemochromatosis (HH) is a hereditary disorder of iron metabolism. It is classified into 4 main types depending on the underlying genetic mutation: human hemochromatosis protein (HFE) (type 1), hemojuvelin (HJV) (type 2A), HAMP (type 2B)...

Iduronate-2-sulfatase fused with anti-hTfR antibody, pabinafusp alfa, for MPS-II: A pha...
https://doi.org/10.1016/j.ymthe.2021.03.019
Molecular Therapy : the Journal of the American Society O... Giugliani R, Martins AM et. al.

Mar 30th, 2021 - In Hunter syndrome (mucopolysaccharidosis II [MPS-II]), systemic accumulation of glycosaminoglycans (GAGs) due to a deficiency of iduronate-2-sulfatase (IDS), caused by mutations in the IDS gene, leads to multiple somatic manifestations and in pat...

Prevalence and associated factors of iron deficiency in Spanish children aged 1 to 11 y...
https://doi.org/10.1007/s00431-021-04037-8 10.1017/S1368980008002401 10.1542/peds.2010-2576 10.1097/MPG.0000000000000206 10.1097/MPG.0b013e3181adaee0 10.1016/j.anpedi.2011.01.036 10.1007/s00431-020-03597-5 10.1159/000371357 10.1097/MPG.0000000000001015 10.1111/j.1651-2227.2001.tb00787.x 10.1542/peds.2007-0572 10.3945/ajcn.117.155978 10.1016/j.jpeds.2007.09.048 10.1542/peds.2009-2097 10.1007/s12031-019-01276-1 10.1108/NFS-01-2018-0005 10.1111/ijlh.12013 10.1097/MPH.0000000000000639 10.1182/blood.V75.9.1870.1870 10.1016/S0009-8981(03)00005-6 10.3109/10408363.2010.550461 10.1097/MPH.0b013e31802d751a 10.3109/08880018.2015.1138007 10.1002/ajh.22108 10.1007/s00431-018-3257-0 10.1136/bmj.320.7244.1240 10.20960/nh.308 10.1080/10408398.2012.742860 10.1001/jama.277.12.973 10.1179/1607845413Y.0000000124 10.1001/archpedi.162.4.374 10.1542/peds.110.3.545 10.1111/j.1651-2227.2004.tb02983.x 10.1038/sj.ejcn.1601594 10.1097/MPG.0b013e3182a80c42 10.1017/S1368980000000501 10.1097/MPG.0000000000000216 10.1017/S0007114511005952 10.3889/MJMS.1857-5773.2011.0155 10.1001/jama.294.8.924 10.1038/ejcn.2014.70
European Journal of Pediatrics; López-Ruzafa E, Vázquez-López MA et. al.

Mar 24th, 2021 - Iron deficiency (ID) is the most common nutritional deficiency affecting children worldwide. Most traditional laboratory parameters to assess ID can be altered by infections or other inflammatory states, including obesity. The aims of this study w...

see more →

News  1 results

Biological Response Modifiers in Cancer
https://www.medscape.com/viewarticle/545538_10

Nov 13th, 2006 - Epratuzumab Epratuzumab (LL2) is a murine IgG2a antibody targeted against CD22 antigen (transferrin receptor). It is widely expressed during B-cell development and is present in most of NHL tumours[64] Juweid and colleagues[65] compared 131ILL2 wi...

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