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ALLMedicine™ Activated Clotting Time Center

Research & Reviews  314 results

Heparin Resistance During Cardiopulmonary Bypass in Adult Cardiac Surgery.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9225936
Journal of Cardiothoracic and Vascular Anesthesia; Chen Y, Phoon PHY et. al.

Aug 5th, 2022 - The use of heparin for anticoagulation has changed the face of cardiac surgery by allowing a bloodless and motionless surgical field throughout the introduction of cardiopulmonary bypass (CPB). However, heparin is a drug with complex pharmacologic...

Renal Artery Angioplasty Technique
https://emedicine.medscape.com/article/1817671-technique

Aug 1st, 2022 - Renal Artery Angioplasty and Stenting For a percutaneous transluminal renal angioplasty (PTRA), the patient is sterilely prepared and draped, conscious sedation is employed, a local anesthetic (lidocaine 1% or 2% solution) is infiltrated at the fe...

ADAPT Transcatheter Aortic Valve Intervention (TAVI & Chronic Total Occlusion Percutaneous Coronary Intervention (CTO PCI)
https://clinicaltrials.gov/ct2/show/NCT05259241

Jul 27th, 2022 - The choice of antithrombotic regimen during TAVI and CTO PCI includes the use of unfractionated heparin. Heparin is the preferred anticoagulant drug in these percutaneous cardiac interventions aiming for an Activated Clotting Time (ACT) > 200sec o...

The Role of Ketamine and Dexmedetomidine in Opioid-Sparing Analgesia
https://clinicaltrials.gov/ct2/show/NCT05474183

Jul 26th, 2022 - In this study, the investigator hypothesizes that by using continuous infusion of ketamine or dexmedetomidine in addition to NSAIDs, the investigator can reduce or completely eliminate opioid use in adult patients after cardiac surgery. The anesth...

Bivalirudin anticoagulation in neonates and infants undergoing cardiac surgery.
https://doi.org/10.1053/j.jvca.2022.04.044
Journal of Cardiothoracic and Vascular Anesthesia; Hasija S, Hote MP et. al.

Jul 12th, 2022 - To determine the dosage of bivalirudin as the anticoagulant for cardiac surgery in neonates and infants. Pilot study. Tertiary-care hospital. Twenty-five neonates and infants with congenital heart disease (CHD) undergoing cardiac surgery. The chil...

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Drugs  1 results see all →

Clinicaltrials.gov  79 results

ADAPT Transcatheter Aortic Valve Intervention (TAVI & Chronic Total Occlusion Percutaneous Coronary Intervention (CTO PCI)
https://clinicaltrials.gov/ct2/show/NCT05259241

Jul 27th, 2022 - The choice of antithrombotic regimen during TAVI and CTO PCI includes the use of unfractionated heparin. Heparin is the preferred anticoagulant drug in these percutaneous cardiac interventions aiming for an Activated Clotting Time (ACT) > 200sec o...

The Role of Ketamine and Dexmedetomidine in Opioid-Sparing Analgesia
https://clinicaltrials.gov/ct2/show/NCT05474183

Jul 26th, 2022 - In this study, the investigator hypothesizes that by using continuous infusion of ketamine or dexmedetomidine in addition to NSAIDs, the investigator can reduce or completely eliminate opioid use in adult patients after cardiac surgery. The anesth...

HEParin Antagonisation in Transcatheter Aortic Valve Implantation
https://clinicaltrials.gov/ct2/show/NCT05422170

Jul 5th, 2022 - Unfractioned heparin is usually given in a defined dosage during transfemoral TAVI. Activated Clotting Time (ACT) is usually used to measure the heparin effect. ACT-analysis is easy to perform at the bedside, but susceptible to interference effect...

Prospective Investigation of Antithrombin III Deficiency in Adult Patients With ECMO
https://clinicaltrials.gov/ct2/show/NCT04879550

May 24th, 2022 - ECMO is applied in patients with acute severe heart or lung failure. The treatment protocol of patients undergoing ECMO is carefully arranged against the risk of bleeding / thrombosis. According to the general protocol, heparin infusion therapy is...

Ventilation During Cardiopulmonary Bypass
https://clinicaltrials.gov/ct2/show/NCT04962542

Apr 25th, 2022 - Our study is designed to determine the effect of different strategies of ventilation during CPB on arterial oxygenation and PPD in pediatrics undergoing corrective cardiac surgeries for non-cyanotic congenital anomalies. Preoperative: First, a pro...

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News  20 results

Cardiopulmonary Bypass in Adult Cardiac Surgery Clinical Practice Guidelines (2019)
https://www.medscape.com/viewarticle/920531

Nov 4th, 2019 - The guidelines on cardiopulmonary bypass (CPB) in adult cardiac surgery were released on October 2, 2019, by the European Association for Cardio-Thoracic Surgery (EACTS), the European Association of Cardiothoracic Anaesthesiology (EACTA), and the ...

Heparin Dosing Oddities in the Cath Lab: A 'Red Flag' Raises Questions
https://www.staging.medscape.com/viewarticle/918035

Sep 10th, 2019 - The peculiar heparin behavior started about 6 months ago. Dosing that had been reliable countless times in the cath lab was failing to get the activated clotting time (ACT) to target, forcing extra boluses. "I called my pharmacy and asked them to ...

Heparin Dosing Oddities in the Cath Lab: A 'Red Flag' Raises Questions
https://www.medscape.com/viewarticle/918035

Sep 10th, 2019 - The peculiar heparin behavior started about 6 months ago. Dosing that had been reliable countless times in the cath lab was failing to get the activated clotting time (ACT) to target, forcing extra boluses. "I called my pharmacy and asked them to ...

ELIMINATE-AF: Edoxaban Viable Alternative to VKA in AF Ablation
https://www.medscape.com/viewarticle/911264

Apr 3rd, 2019 - LISBON — Uninterrupted, once-daily edoxaban (Savaysa, Daiichi Sankyo) compared favorably with uninterrupted vitamin K antagonists (VKAs) in terms of efficacy and safety during and after catheter ablation in patients with atrial fibrillation (AF), ...

First Cardiopulmonary Bypass Anticoagulation Guidelines Issued
https://www.medscape.com/viewarticle/891656

Jan 23rd, 2018 - CHICAGO — The Society of Thoracic Surgeons (STS), the Society of Cardiovascular Anesthesiologists (SCA), and the American Society of ExtraCorporeal Technology (AmSECT) have published the first clinical practice guidelines for anticoagulation thera...

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