ALLMedicine™ Activated Protein C Resistance Center
Research & Reviews 11 results
Seminars in Thrombosis and Hemostasis; Pengo V
Jan 13th, 2022 - Thrombotic antiphospholipid syndrome (APS) is a condition in which thrombosis in venous, arterial, and/or small vessels is ascribed to the presence of antiphospholipid antibodies (aPL). Among the various proposed pathogenic theories to explain thr...
Clinical Chemistry and Laboratory Medicine; Favaloro EJ, Mohammed S et. al.
Jun 12th, 2021 - Thrombophilia testing is commonly performed within hemostasis laboratories, and the ACL TOP 50 family of instruments represent a new 'single platform' of hemostasis instrumentation. The study objective was to evaluate these instruments and manufac...
Journal of Thrombosis and Haemostasis : JTH; Pontara E, Cattini MG et. al.
Nov 30th, 2020 - Most high-risk thrombotic antiphospholipid syndrome (APS) patients test positive for anti-β2-glycoprotein I (aβ2GPI) and anti-phosphatidylserine/prothrombin (aPS/PT) antibodies. Information on the influence of these antibodies on thrombin generati...
Clinical Chemistry and Laboratory Medicine; Favaloro EJ, Gilmore G et. al.
Mar 4th, 2020 - Background Investigation of hemostasis is problematic when patients are on anticoagulant therapy. Rivaroxaban especially causes substantial interference, extending many clot-based tests, thereby leading to false positive or negative events. In par...
Archives of Pathology & Laboratory Medicine; Maryamchik E, Van Cott EM
Feb 27th, 2020 - Apixaban causes a false increase in activated protein C resistance (APCR) ratios and possibly protein S activity. To investigate whether this increase can mask a diagnosis of factor V Leiden (FVL) or protein S deficiency in an actual population of...