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About 33 results

ALLMedicine™ Activated Protein C Resistance Center

Research & Reviews  13 results

Short-term biological variation study of plasma hemophilia and thrombophilia parameters...
https://doi.org/10.1515/cclm-2022-0377
Clinical Chemistry and Laboratory Medicine; Brochier A, Mairesse A et. al.

Jun 26th, 2022 - Biological variation (BV) data obtained in a standardized way is valuable to assess the analytical requirements and the utility of a reference interval. Our study aimed to determine the short-term BV of thrombophilia (protein S, protein C, activat...

Interaction between Antiphospholipid Antibodies and Protein C Anticoagulant Pathway: A ...
https://doi.org/10.1055/s-0041-1742083
Seminars in Thrombosis and Hemostasis; Pengo V

Jan 13th, 2022 - Thrombotic antiphospholipid syndrome (APS) is a condition in which thrombosis in venous, arterial, and/or small vessels is ascribed to the presence of antiphospholipid antibodies (aPL). Among the various proposed pathogenic theories to explain thr...

A multi-laboratory assessment of congenital thrombophilia assays performed on the ACL T...
https://doi.org/10.1515/cclm-2021-0499
Clinical Chemistry and Laboratory Medicine; Favaloro EJ, Mohammed S et. al.

Jun 12th, 2021 - Thrombophilia testing is commonly performed within hemostasis laboratories, and the ACL TOP 50 family of instruments represent a new 'single platform' of hemostasis instrumentation. The study objective was to evaluate these instruments and manufac...

Insight into the hypercoagulable state of high-risk thrombotic APS patients: Contributi...
https://doi.org/10.1111/jth.15199
Journal of Thrombosis and Haemostasis : JTH; Pontara E, Cattini MG et. al.

Nov 30th, 2020 - Most high-risk thrombotic antiphospholipid syndrome (APS) patients test positive for anti-β2-glycoprotein I (aβ2GPI) and anti-phosphatidylserine/prothrombin (aPS/PT) antibodies. Information on the influence of these antibodies on thrombin generati...

Laboratory testing for activated protein C resistance: rivaroxaban induced interference...
https://doi.org/10.1515/cclm-2019-1160
Clinical Chemistry and Laboratory Medicine; Favaloro EJ, Gilmore G et. al.

Mar 4th, 2020 - Background Investigation of hemostasis is problematic when patients are on anticoagulant therapy. Rivaroxaban especially causes substantial interference, extending many clot-based tests, thereby leading to false positive or negative events. In par...

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