About 3,208 results

ALLMedicine™ Antiphospholipid Antibodies Center

Research & Reviews  1,116 results

The third inactivated vaccine booster dramatically enhanced SARS-CoV-2 antibody respons...
Journal of Medical Virology; Pan Y, Wang S et. al.

Nov 29th, 2022 - The purpose of this study is to investigate the production of both SARS-CoV-2-specific antibodies and autoantibodies in serum following the third booster vaccination of the inactivated COVID-19 vaccine, and to study the effect of B cell subsets wi...

Antiphospholipid antibodies in autoimmune thyroid diseases.
Journal of Clinical Laboratory Analysis; Mankaï A, Melayah S et. al.

Nov 26th, 2022 - Antiphospholipid (aPL) antibodies have been reported in several autoimmune diseases. The aim of this study was to evaluate the frequency of aPL (anti-cardiolipin antibodies (aCL) and anti-β2 glycoprotein I antibodies (aβ2GPI)) in patients with aut...

Venous Thromboembolism in the Inflammatory Rheumatic Diseases.
Rheumatic Diseases Clinics of North America; Misra DP, Ahmed S et. al.

Nov 25th, 2022 - Venous thromboembolism (VTE), which includes deep venous thrombosis and pulmonary embolism, is a cardiovascular event whose risk is increased in most inflammatory rheumatic diseases (IRDs). Mechanisms that increase VTE risk include antiphospholipi...

Acute coronary syndromes in Antiphospholipid syndrome-above suspicion: a systematic rev...
Current Problems in Cardiology; Vasileios N, Nikias M et. al.

Nov 20th, 2022 - Antiphospholipid syndrome is an autoimmune disorder characterized clinically by vascular thrombosis and/or pregnancy morbidity, associated with persistently elevated titers of antiphospholipid antibodies on at least two measurements over 12 weeks ...

Preclinical ocular changes in systemic lupus erythematosus patients by optical coherenc...
Rheumatology (Oxford, England); Pelegrín L, Morató M et. al.

Nov 5th, 2022 - The aim of the present study was to detect preclinical changes in SLE patients in retinal microvascularization or retinal and optical nerve structure by optical coherence tomography. This cross-sectional, single-center study aimed to describe stru...

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Guidelines  3 results

Practice Bulletin No. 132: Antiphospholipid syndrome.
Obstetrics and Gynecology;

Nov 22nd, 2012 - Antiphospholipid syndrome (APS) is an autoimmune disorder defined by the presence of characteristic clinical features and specified levels of circulating antiphospholipid antibodies (Box 1 and Box 2). Diagnosis requires that at least one clinical ...

EULAR recommendations for the management of systemic lupus erythematosus with neuropsyc...
Annals of the Rheumatic Diseases; Bertsias GK, Ioannidis JP et. al.

Aug 21st, 2010 - To develop recommendations for the diagnosis, prevention and treatment of neuropsychiatric systemic lupus erythematosus (NPSLE) manifestations. The authors compiled questions on prevalence and risk factors, diagnosis and monitoring, therapy and pr...

EFNS guideline on the treatment of cerebral venous and sinus thrombosis in adult patients.
European Journal of Neurology; Einhäupl K, Stam J et. al.

Apr 21st, 2010 - Cerebral venous and sinus thrombosis (CVST) is a rather rare disease which accounts for <1% of all strokes. Diagnosis is still frequently overlooked or delayed as a result of the wide spectrum of clinical symptoms and the often subacute or lingeri...

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Clinicaltrials.gov  49 results

Longitudinal Study of the Clinical and Haematological Cause of Women With Antiphospholipid Antibodies.

Aug 8th, 2022 - The association between APA and thrombosis is well documented. Both LA and ACA are often detected in individuals with SLE but there is no prospective data on the risk of thrombosis in women who present with recurrent miscarriages in association wi...

Efficacy of Prolonged Anticoagulation for Primary Prevention of Venous Thromboembolic Disease in Autoimmune Hemolytic Anemia: a Prospective, Phase II, Randomized, Multicenter Study

Jul 6th, 2022 - Autoimmune hemolytic anemia (AIHA) is a rare autoimmune disease (incidence <1/100,000 population) responsible for the destruction of red blood cells by the host immune system, notably through the action of autoantibodies. Apart from complications ...

The Lupus prEGnAnCY Cohort: An International Prospective Cohort of Lupus Pregnancies

Jun 24th, 2022 - Systemic lupus erythematosus (SLE) predominantly affects women during their reproductive years. As SLE is associated with substantial fetal and maternal morbidity during pregnancy and beyond it is crucial to identify predictors of adverse pregnanc...

Safety and Efficacy of Zanubrutinib in the Treatment of Antiphospholipid Syndrome With Secondary Thrombocytopenia

May 27th, 2022 - Antiphospholipid syndrome (APS) is a disease spectrum characterized by thrombosis and/or pathological pregnancy, and characterized by persistent antiphospholipid antibodies (APL) positive in laboratory examination. The incidence of thrombocytopeni...

Placental Pathology and Inflammatory Factor Analysis of OAPS

May 18th, 2022 - 1. To clarify the correlation between antiphospholipid antibody, ACC1 expression level, Treg cell and placental pathological changes associated with antiphospholipid syndrome. 2. Reveal that antiphospholipid antibodies affect Treg cell differentia...

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News  112 results

New Lyme Disease Test Brings Faster Diagnosis, Can Detect Recurrence

Apr 4th, 2022 - NEW YORK (Reuters Health) - A test that detects antiphospholipid antibodies in the blood of Lyme disease patients shows potential for identifying the disease sooner than current methods and possibly tracking response to therapy and recurrence, res...

Mixed Results for Oral Lupus Drug in Phase II

Mar 16th, 2022 - What could be the first oral medication specific for systemic lupus erythematosus (SLE) was more effective than placebo in a randomized phase II trial, though the results were something less than a home run. With 288 patients assigned to three dos...

Standard Anticoagulation May Be Overkill for Pediatric VTE

Jan 11th, 2022 - For children being treated for a provoked venous thromboembolism (VTE), a shortened course of anticoagulation struck a good balance between efficacy and safety, the small Kids-DOTT trial showed. Six weeks of anticoagulant therapy met noninferiorit...

Low Preconception Complement Levels Linked to Adverse Pregnancy Outcomes in Antiphospholipid Syndrome

Oct 11th, 2021 - Low serum levels of two complement proteins are linked to worse pregnancy outcomes in women with antiphospholipid syndrome (APS), the results of a multicenter study appear to confirm. The study evaluated preconception complement levels in 260 preg...

An otherwise healthy 1-month-old female presents with lesions on the face, scalp, and chest
Catalina Matiz, MD, Ayan Kusari

Jun 15th, 2021 - A potassium hydroxide preparation (KOH) from skin scrapings from the scalp lesions demonstrated no fungal elements. Further laboratory work up revealed a normal blood cell count, normal liver enzymes, an antinuclear antibody (ANA) titer of less th.

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Patient Education  3 results see all →