About 3,098 results

ALLMedicine™ Antiphospholipid Antibodies Center

Research & Reviews  1,078 results

Right Atrial Thrombus Mimicking a Myxoma: Synergism of Hormonal Contraceptives and Anti...
Texas Heart Institute Journal; Hashmath Z, Bose A et. al.

Aug 9th, 2022 - Cardiac thrombus, the most common intracardiac mass, is typically seen in the left side of the heart in the presence of atrial fibrillation, mitral stenosis, or impaired global wall motion. Right atrial thrombus, which is rarer, is usually associa...

Pregnancy in patients with systemic lupus erythematosus: a systematic review.
Archives of Gynecology and Obstetrics; Zhang S, Han X et. al.

Aug 2nd, 2022 - Systemic lupus erythematosus (SLE)-a most common disorder in women of reproductive age-has been described to be associated with adverse pregnancy outcomes. Despite the increased health risks for the mother (preeclampsia, lupus flare, arterial hype...

Increased risk of acute and chronic microvascular renal lesions associated with antipho...
Autoimmunity Reviews; Domingues V, Chock EY et. al.

Jul 31st, 2022 - Microvascular renal lesions have been described in patients with antiphospholipid antibodies (aPL), however their association with aPL is inconsistent among studies. Therefore, our objective was to investigate associations between microvascular re...

Predictors and prognostic stratification for lupus low disease activity state: Results ...
Rheumatology (Oxford, England); Zhang K, An Y et. al.

Jul 28th, 2022 - Identify predictors for lupus low disease activity state (LLDAS), early-achieved LLDAS, and long-term disease activity and refine a prognostic stratification tool for use in active systemic lupus erythematosus (SLE) patients. A total of 245 active...

Presence of antiphospholipid antibodies is associated with increased implantation failu...
PloS One; Papadimitriou E, Boutzios G et. al.

Jul 28th, 2022 - A systematic review and meta-analysis was conducted comparing the presence of anti-phospholipid (anti-PL) antibodies between women of reproductive age, without diagnosis of antiphospholipid syndrome, who experienced at least two implantation failu...

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Guidelines  3 results

Practice Bulletin No. 132: Antiphospholipid syndrome.
Obstetrics and Gynecology;

Nov 22nd, 2012 - Antiphospholipid syndrome (APS) is an autoimmune disorder defined by the presence of characteristic clinical features and specified levels of circulating antiphospholipid antibodies (Box 1 and Box 2). Diagnosis requires that at least one clinical ...

EULAR recommendations for the management of systemic lupus erythematosus with neuropsyc...
Annals of the Rheumatic Diseases; Bertsias GK, Ioannidis JP et. al.

Aug 21st, 2010 - To develop recommendations for the diagnosis, prevention and treatment of neuropsychiatric systemic lupus erythematosus (NPSLE) manifestations. The authors compiled questions on prevalence and risk factors, diagnosis and monitoring, therapy and pr...

EFNS guideline on the treatment of cerebral venous and sinus thrombosis in adult patients.
European Journal of Neurology; Einhäupl K, Stam J et. al.

Apr 21st, 2010 - Cerebral venous and sinus thrombosis (CVST) is a rather rare disease which accounts for <1% of all strokes. Diagnosis is still frequently overlooked or delayed as a result of the wide spectrum of clinical symptoms and the often subacute or lingeri...

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Clinicaltrials.gov  49 results

Efficacy of Prolonged Anticoagulation for Primary Prevention of Venous Thromboembolic Disease in Autoimmune Hemolytic Anemia: a Prospective, Phase II, Randomized, Multicenter Study

Jul 6th, 2022 - Autoimmune hemolytic anemia (AIHA) is a rare autoimmune disease (incidence <1/100,000 population) responsible for the destruction of red blood cells by the host immune system, notably through the action of autoantibodies. Apart from complications ...

The Lupus prEGnAnCY Cohort: An International Prospective Cohort of Lupus Pregnancies

Jun 24th, 2022 - Systemic lupus erythematosus (SLE) predominantly affects women during their reproductive years. As SLE is associated with substantial fetal and maternal morbidity during pregnancy and beyond it is crucial to identify predictors of adverse pregnanc...

Safety and Efficacy of Zanubrutinib in the Treatment of Antiphospholipid Syndrome With Secondary Thrombocytopenia

May 27th, 2022 - Antiphospholipid syndrome (APS) is a disease spectrum characterized by thrombosis and/or pathological pregnancy, and characterized by persistent antiphospholipid antibodies (APL) positive in laboratory examination. The incidence of thrombocytopeni...

Placental Pathology and Inflammatory Factor Analysis of OAPS

May 18th, 2022 - 1. To clarify the correlation between antiphospholipid antibody, ACC1 expression level, Treg cell and placental pathological changes associated with antiphospholipid syndrome. 2. Reveal that antiphospholipid antibodies affect Treg cell differentia...

Precision Medicine in LN: A Multicenter Proof-of-concept Study for Histopathological Biomarkers Analysis in Renal Biopsy

May 3rd, 2022 - Sample size For this proof-of-concept study, our objective is to analyze around 60 renal biopsy samples (expandable according to the results obtained). Methods: The following general variables will be collected: demographic data: age, sex, ethnici...

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News  107 results

New Lyme Disease Test Brings Faster Diagnosis, Can Detect Recurrence

Apr 4th, 2022 - NEW YORK (Reuters Health) - A test that detects antiphospholipid antibodies in the blood of Lyme disease patients shows potential for identifying the disease sooner than current methods and possibly tracking response to therapy and recurrence, res...

Mixed Results for Oral Lupus Drug in Phase II

Mar 16th, 2022 - What could be the first oral medication specific for systemic lupus erythematosus (SLE) was more effective than placebo in a randomized phase II trial, though the results were something less than a home run. With 288 patients assigned to three dos...

Low Preconception Complement Levels Linked to Adverse Pregnancy Outcomes in Antiphospholipid Syndrome

Oct 11th, 2021 - Low serum levels of two complement proteins are linked to worse pregnancy outcomes in women with antiphospholipid syndrome (APS), the results of a multicenter study appear to confirm. The study evaluated preconception complement levels in 260 preg...

An otherwise healthy 1-month-old female presents with lesions on the face, scalp, and chest
Catalina Matiz, MD, Ayan Kusari

Jun 15th, 2021 - A potassium hydroxide preparation (KOH) from skin scrapings from the scalp lesions demonstrated no fungal elements. Further laboratory work up revealed a normal blood cell count, normal liver enzymes, an antinuclear antibody (ANA) titer of less th.

Relapsing Lupus Nephritis and Cutaneous Vasculitis: A Race to Contain B Cells

Apr 28th, 2021 - This article originally appeared on the Hospital for Special Surgery's website. Case Report A 45-year-old woman with a history of systemic lupus erythematosus (SLE) since 2006 came to the Hospital for Special Surgery in 2014 for continued manageme...

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Patient Education  2 results see all →