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About 2,640 results

ALLMedicine™ Antiphospholipid Antibodies Center

Research & Reviews  951 results

Antiphospholipid syndrome-mediated acute cerebrovascular diseases and long-term outcomes.
https://doi.org/10.1177/09612033221074178
Lupus García-Grimshaw M, Posadas-Pinto DR et. al.

Jan 20th, 2022 - The antiphospholipid syndrome (APS) is an autoimmune disease associated with thrombotic and non-thrombotic neurologic manifestations. APS is classified as primary (PAPS) or secondary (SAPS) when it co-exists with another autoimmune disease. We aim...

Antiphospholipid antibodies increase endometrial stromal cell decidualization, senescen...
https://doi.org/10.1002/art.42068
Arthritis & Rheumatology (Hoboken, N.J.); Tong M, Kayani T et. al.

Jan 20th, 2022 - Miscarriage affects one in seven pregnancies and antiphospholipid autoantibodies (aPL) are one of the biggest risk factors for recurrent pregnancy loss. While aPL target the endometrial stroma, little is known about their impact. Endometrial strom...

Antiphospholipid antibodies do not cause retargeting of placental extracellular vesicle...
https://doi.org/10.1016/j.placenta.2022.01.008
Placenta Tsai BW, Lau S et. al.

Jan 19th, 2022 - Antiphospholipid antibodies (aPL) are autoantibodies that cause pregnancy disorders by a poorly defined mechanism that involves the placenta. The human placenta is covered by a single multinucleated cell, the syncytiotrophoblast, which extrudes va...

Antiphospholipid antibodies in the obstetric antiphospholipid syndrome: Detection and a...
https://doi.org/10.1111/jog.15143
The Journal of Obstetrics and Gynaecology Research; Khefacha L, Rassas R et. al.

Jan 19th, 2022 - This study aimed to implement lupus anticoagulant (LAC) detection techniques according to the International Society on Thrombosis and Hemostasis (ISTH) recommendations, in the Biological Laboratory of the Maternity and Neonatal Medicine Center (Mo...

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Guidelines  3 results

Practice Bulletin No. 132: Antiphospholipid syndrome.
https://doi.org/10.1097/01.AOG.0000423816.39542.0f
Obstetrics and Gynecology;

Nov 22nd, 2012 - Antiphospholipid syndrome (APS) is an autoimmune disorder defined by the presence of characteristic clinical features and specified levels of circulating antiphospholipid antibodies (Box 1 and Box 2). Diagnosis requires that at least one clinical ...

EULAR recommendations for the management of systemic lupus erythematosus with neuropsyc...
https://doi.org/10.1136/ard.2010.130476
Annals of the Rheumatic Diseases; Bertsias GK, Ioannidis JP et. al.

Aug 21st, 2010 - To develop recommendations for the diagnosis, prevention and treatment of neuropsychiatric systemic lupus erythematosus (NPSLE) manifestations. The authors compiled questions on prevalence and risk factors, diagnosis and monitoring, therapy and pr...

EFNS guideline on the treatment of cerebral venous and sinus thrombosis in adult patients.
https://doi.org/10.1111/j.1468-1331.2010.03011.x
European Journal of Neurology; Einhäupl K, Stam J et. al.

Apr 21st, 2010 - Cerebral venous and sinus thrombosis (CVST) is a rather rare disease which accounts for <1% of all strokes. Diagnosis is still frequently overlooked or delayed as a result of the wide spectrum of clinical symptoms and the often subacute or lingeri...

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Clinicaltrials.gov  16 results

Observational Study of the Performance of Cephen Reagents in the Context of Research Into Lupus Anticoagulants
https://clinicaltrials.gov/ct2/show/NCT05172778

Dec 29th, 2021 - Lupus anticoagulants (are antiphospholipid antibodies (PSA), the screening of which is done by demonstrating prolongation of coagulation times corrected by the intake of phospholipids (PL). Learned societies (ISTH, CLSI) thus recommend, for the re...

Genetic Risk Factors Associated With Antiphospholipid Antibody Syndrome
https://clinicaltrials.gov/ct2/show/NCT00482794

Aug 10th, 2021 - APS is an autoimmune disorder that causes an increased risk for developing a venous or arterial thromboembolism, as well as recurrent miscarriages. APS frequently occurs in people with lupus, and is referred to as secondary APS in this case. Many ...

Sequelae of Sars-CoV-2 Infections
https://clinicaltrials.gov/ct2/show/NCT04442789

Apr 28th, 2021 - Coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 requires hospitalization in a significant amount of patients. The hospitalization rate and disease severity increases in the elderly and patients with comorbidities such as diabetes, arteria...

The Lupus prEGnAnCY Cohort: An International Prospective Cohort of Lupus Pregnancies
https://clinicaltrials.gov/ct2/show/NCT03746028

Feb 24th, 2021 - Systemic lupus erythematosus (SLE) predominantly affects women during their reproductive years. As SLE is associated with substantial fetal and maternal morbidity during pregnancy and beyond it is crucial to identify predictors of adverse pregnanc...

Low Dose Prednisone Therapy in Women With Recurrent Pregnancy Loss
https://clinicaltrials.gov/ct2/show/NCT04558268

Sep 22nd, 2020 - Recurrent pregnancy loss (RPL) was defined recently by the European society of human reproduction and embryology (ESHRE) as the loss of two or more pregnancies that occur after spontaneous conception and assisted reproductive technology excluding ...

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News  86 results

Low Preconception Complement Levels Linked to Adverse Pregnancy Outcomes in Antiphospholipid Syndrome
https://www.medscape.com/viewarticle/960632

Oct 11th, 2021 - Low serum levels of two complement proteins are linked to worse pregnancy outcomes in women with antiphospholipid syndrome (APS), the results of a multicenter study appear to confirm. The study evaluated preconception complement levels in 260 preg...

An otherwise healthy 1-month-old female presents with lesions on the face, scalp, and chest
https://www.mdedge.com/pediatrics/article/241532/dermatology/otherwise-healthy-1-month-old-female-presents-lesions-face
Catalina Matiz, MD, Ayan Kusari

Jun 15th, 2021 - A potassium hydroxide preparation (KOH) from skin scrapings from the scalp lesions demonstrated no fungal elements. Further laboratory work up revealed a normal blood cell count, normal liver enzymes, an antinuclear antibody (ANA) titer of less th.

Relapsing Lupus Nephritis and Cutaneous Vasculitis: A Race to Contain B Cells
https://www.medscape.com/viewarticle/949863

Apr 28th, 2021 - This article originally appeared on the Hospital for Special Surgery's website. Case Report A 45-year-old woman with a history of systemic lupus erythematosus (SLE) since 2006 came to the Hospital for Special Surgery in 2014 for continued manageme...

Managing Diffuse Peripheral Ischemia in Antiphospholipid Syndrome: Anticoagulation, Immunosuppression, or Vasodilation?
https://www.medscape.com/viewarticle/948988

Apr 14th, 2021 - This article originally appeared on Hospital for Special Surgery's website. Case Report A 39-year-old man with a history of well-controlled type 1 diabetes (T1D) since childhood and migraine presented with 1 week of pain and cyanosis of the finger...

Managing Diffuse Peripheral Ischemia in Antiphospholipid Syndrome: Anticoagulation, Immunosuppression, or Vasodilation?
https://www.medscape.com/viewarticle/948988?src=sapfe

Apr 14th, 2021 - This article originally appeared on Hospital for Special Surgery's website. Case Report A 39-year-old man with a history of well-controlled type 1 diabetes (T1D) since childhood and migraine presented with 1 week of pain and cyanosis of the finger...

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