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ALLMedicine™ Clot Retraction Center

Research & Reviews  85 results

Clot Retraction
http://emedicine.medscape.com/article/2085066-overview

May 17th, 2022 - Reference Range Normal clot retraction time is 0-2 hours. If the weight of the clot or the percent of extruded serum is used as the end measure, the result depends on the volume of the specimen used, which varies from laboratory to laboratory. [1]...

Inhibition of HIF prolyl hydroxylase modulates platelet function.
https://doi.org/10.1055/a-1837-7797
Thrombosis and Haemostasis; Gu W, Qi J et. al.

Apr 28th, 2022 - Hypoxia-inducible factors-1α (HIF-1α) involves in redox reaction. Considering the role of reactive oxygen species (ROS) in platelet function, whether it regulates platelet function remains unclear. Using an inhibitor of HIF prolyl hydroxylase IOX-...

Platelet-inspired nanomedicine in hemostasis thrombosis and thromboinflammation.
https://doi.org/10.1111/jth.15734
Journal of Thrombosis and Haemostasis : JTH; Raghunathan S, Rayes J et. al.

Apr 19th, 2022 - Platelets are anucleate cell-fragments derived predominantly from megakaryocytes in the bone marrow and released in the blood circulation, with a normal count of 150 000-40 000 per μl and a lifespan of approximately 10 days in humans. A primary ro...

Cucurbitacins elicit anti-platelet activity via perturbation of the actin cytoskeleton ...
https://doi.org/10.1055/a-1788-5322
Thrombosis and Haemostasis; Kriek N, Nock S et. al.

Mar 8th, 2022 - Cucurbitacins are dietary compounds that have been shown to elicit a range of anti-tumour, anti-inflammatory and anti-atherosclerotic activities. Originally identified as STAT inhibitors, a variety of mechanisms of action have since been described...

Platelet binding to polymerizing fibrin is avidity driven and requires activated αIIbβ3...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945615
Blood Advances; Buitrago L, Lefkowitz S et. al.

Oct 15th, 2021 - The molecular basis of platelet-fibrin interactions remains poorly understood despite the predominance of fibrin in thrombi. We have studied the interaction of platelets with polymerizing fibrin by adding thrombin to washed platelets in the presen...

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