About 15,293 results

ALLMedicine™ Fibrinogen Center

Research & Reviews  5,339 results

IgG-RBD Response Due to Inactivated SARS-CoV-2 Vaccine: Alteration in D-Dimer and Fibri...
Laboratory Medicine; Kaytaz M, Akkaya E et. al.

Jun 29th, 2022 - To examine the immunoglobulin G-receptor-binding domain (IgG-RBD) response and changes in fibrinogen and D-dimer concentrations in individuals with a past coronavirus infection and followed by CoronaVac. The study consisted of a total of 116 parti...

LAG3 ectodomain structure reveals functional interfaces for ligand and antibody recogni...
https://doi.org/10.1038/s41590-022-01238-7 10.1038/s41467-020-17670-y 10.1038/nrc.2016.36 10.1038/ni.2762 10.1038/nri3790 10.1038/s41590-018-0257-1 10.3390/ijms22010075 10.1084/jem.20100466 10.1126/sciimmunol.aah4569 10.1126/sciimmunol.abc2728 10.1038/s41467-021-25865-0 10.1056/NEJMoa2109970 10.1016/j.coi.2020.06.001 10.1038/ncomms11639 10.4049/jimmunol.1900823 10.1002/eji.1830250949 10.1136/jitc-2020-001014 10.1016/j.jim.2018.02.003 10.4049/jimmunol.169.10.5392 10.1074/jbc.RA119.007455 10.1002/eji.1830241246 10.1093/intimm/5.6.695 10.1038/s41590-018-0217-9 10.1073/pnas.94.11.5744 10.3389/fimmu.2020.615317 10.1016/j.cell.2018.11.010 10.1158/0008-5472.CAN-13-2690 10.1158/2326-6066.CIR-14-0150 10.1126/science.aah3374 10.1073/pnas.2011196118 10.1186/s12896-019-0559-x 10.1016/S0006-3495(85)83877-7 10.1093/protein/14.6.421 10.1073/pnas.191124098 10.4049/jimmunol.173.11.6806 10.1002/eji.1830261030 10.1002/eji.200324669 10.1002/eji.202048753 10.1182/blood-2003-05-1491 10.1107/S0907444904026460 10.1074/jbc.M113.520577 10.1073/pnas.1616166114 10.1016/j.biocel.2016.10.008 10.1126/science.aav7532 10.1038/ncomms8380 10.1073/pnas.1617800114 10.1002/1521-4141(2001010)31:10<2885::AID-IMMU2885>3.0.CO;2-2 10.1016/j.bbrc.2007.11.069 10.1016/S0076-6879(97)76066-X 10.1107/S0907444906019949 10.1107/S0021889807021206 10.1038/nprot.2015.053 10.1107/S0907444909052925 10.1107/S0907444904019158 10.1016/j.jmb.2007.05.022 10.1093/bioinformatics/btg137 10.1016/j.jmb.2015.09.014 10.3389/fmolb.2021.729513
Nature Immunology; Ming Q, Celias DP et. al.

Jun 28th, 2022 - The immune checkpoint receptor lymphocyte activation gene 3 protein (LAG3) inhibits T cell function upon binding to major histocompatibility complex class II (MHC class II) or fibrinogen-like protein 1 (FGL1). Despite the emergence of LAG3 as a ta...

Hyperbaric effects on cold stored whole blood following a military dive mission profile.
Transfusion Scheiber CJ, Spencer CM et. al.

Jun 25th, 2022 - Whole blood (WB) is carried by special operations forces as part of a remote damage control resuscitation strategy. The effects of an underwater mission on the quality and coagulation profile of WB were simulated by exposure to hyperbaric pressure...

In vitro quality and hemostatic function of cold-stored CPDA-1 whole blood after repeat...
Transfusion Sivertsen J, Hervig T et. al.

Jun 25th, 2022 - Blood products are frequently exposed to room temperature or higher for longer periods than permitted by policy. We aimed to investigate if this resulted in a measurable effect on common quality parameters and viscoelastic hemostatic function of c...

D-dimer and outcomes in hospitalized heart failure patients across the ejection fractio...
ESC Heart Failure; Huang L, Liang L et. al.

Jun 25th, 2022 - The prognostic significance of D-dimer in hospitalized heart failure (HF) patients is incompletely characterized. We aimed to assess the association of D-dimer levels on admission with adverse events at follow-up in patients hospitalized with HF a...

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Guidelines  3 results

Postpartum hemorrhage: guidelines for clinical practice from the French College of Gyna...
European Journal of Obstetrics, Gynecology, and Reproduct... Sentilhes L, Vayssière C et. al.

Jan 17th, 2016 - Postpartum haemorrhage (PPH) is defined as blood loss ≥500mL after delivery and severe PPH as blood loss ≥1000mL, regardless of the route of delivery (professional consensus). The preventive administration of uterotonic agents just after delivery ...

General mechanisms of coagulation and targets of anticoagulants (Section I). Position P...
Thrombosis and Haemostasis; De Caterina R, Husted S et. al.

Mar 1st, 2013 - Contrary to previous models based on plasma, coagulation processes are currently believed to be mostly cell surface-based, including three overlapping phases: initiation, when tissue factor-expressing cells and microparticles are exposed to plasma...

Guidelines for the diagnosis and management of disseminated intravascular coagulation. ...
British Journal of Haematology; Levi M, Toh CH et. al.

Feb 19th, 2009 - The diagnosis of disseminated intravascular coagulation (DIC) should encompass both clinical and laboratory information. The International Society for Thrombosis and Haemostasis (ISTH) DIC scoring system provides objective measurement of DIC. Wher...

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Drugs  29 results see all →

Clinicaltrials.gov  510 results

Association of Cathelicidin and Vitamin D Levels With the Category and Course of COPD

Jun 24th, 2022 - Interventional prospective research design. The study will be conducted on patients with moderate and severe COPD. The material for the study will be the blood and sputum of patients with COPD. Research methods: biochemical, enzyme immunoassay, ba...

MK-7075 (Miransertib) in Proteus Syndrome

Jun 24th, 2022 - Study Description: The primary objective of this study is to determine the response rate of miransertib as measured by the change in CCTN involvement of the plantar surface from baseline, using blinded independent central review of lesional photog...

Effectiveness of Low Level Laser Therapy on Insulin Resistance and Inflammatory Biomarkers

Jun 21st, 2022 - PURPOSE: To determine the effectiveness of low level laser therapy on insulin resistance and inflammatory biomarkers in obese postmenopausal breast cancer risk women BACKGROUND: The American Obesity Association (2002, 2003) defines obesity as 'a c...

Rotational Thromboelastometry Guided Blood Component Use in Children With Cirrhosis Undergoing Invasive Procedures: A Randomized Controlled Trial

Jun 15th, 2022 - Children with cirrhosis listed for invasive procedures and with deranged INR or deranged platelet count will be included in the study and will be block randomized into two groups. To prevent bleeding during the procedure, one group will receive pr...

Efficacy of Ursodeoxycholic Acid (UDCA) in Patients With Type 2 Diabetes

Jun 13th, 2022 - This is a Phase 3, randomized, double-blind, placebo-controlled, evaluation of the efficacy of UDCA on oxidative stress, inflammation, and endothelial dysfunction in combination with metformin after 8 weeks in patients with T2DM who did not meet H...

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News  236 results

24-year-old female presents with a 3-month history of nonpruritic rash
Lynette Xu, Brooke Resh Sateesh, MD

Apr 19th, 2022 - Purpura annularis telangiectodes of Majocchi (PATM) or Majocchi’s disease, is an uncommon subtype of pigmented purpuric dermatosis (PPD) or capillaritis, typically characterized by symmetrical, nonblanching, purpuric, telangiectatic, and atrophic.

Leukemia Cutis Manifesting as Nonpalpable Purpura
Julianne Clowry, MB, BCh, BAO, Laura Nestor, MB, BCh, BAO et. al.

Feb 24th, 2022 - To the Editor: A 72-year-old man presented with symptomatic anemia and nonpalpable purpura of the legs, abdomen, and arms of 2 weeks’ duration (Figure 1). There were no associated perifollicular papules.

Tenecteplase for Stroke Thrombolysis Up to 24 Hours?

Feb 16th, 2022 - The thrombolytic tenecteplase may have a role in reestablishing blood flow in patients with large-vessel acute ischemic stroke up to 24 hours after stroke onset selected by perfusion imaging, a new trial from China suggests. The phase 2a CHABLIS t...

A Starter Guide to Immunofluorescence Testing in Dermatology
Margaret Maria Cocks, MD, PhD

Dec 1st, 2021 - Direct immunofluorescence (DIF) is the go-to diagnostic test when evaluating vesiculobullous eruptions, connective tissue disease, and vasculitis. This specialized test allows visualization of autoantibodies and their reaction products in the epid.

ICH a ffects survival in nonpromyelocytic AML patients receiving intensive chemotherapy

Dec 1st, 2021 - Key clinical point: Intracranial hemorrhage (ICH) is still a deadly complication affecting survival in patients with newly diagnosed nonacute promyelocytic acute myeloid leukemia (AML) receiving intensive induction chemotherapy (IIC) despite routi.

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