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About 1,730 results

ALLMedicine™ Haptoglobin Center

Research & Reviews  645 results

Transcatheter Para-Valvular Leak Closure: An International Prospective Multicentre Registry
https://clinicaltrials.gov/ct2/show/NCT05089136

Nov 19th, 2021 - Prosthetic paravalvular leaks (PVL) are associated with congestive heart failure and haemolysis, for which the standard treatment is open-heart surgery with the attendant risks to the patient. Transcatheter closure has emerged as an alternative. P...

Haptoglobin Phenotype Modifies the Effect of Fenofibrate on Risk of Coronary Event: ACC...
https://doi.org/10.2337/dc21-1429
Diabetes Care; Warren RA, Carew AS et. al.

Nov 18th, 2021 - The haptoglobin (Hp)2-2 phenotype (∼35-40% of people) is associated with increased oxidation and dysfunctional HDL in hyperglycemia and may explain why drugs designed to pharmacologically raise HDL cholesterol and lower triglycerides have not reli...

The Automatically Analyzed (AA) ColonView (CV) Quick Test for Fecal Occult Blood Shows ...
https://doi.org/10.21873/anticanres.15365
Anticancer Research; Meklin J, Eskelinen M et. al.

Nov 5th, 2021 - The present study compared the accuracy of visually analyzed (VA) and automatically analyzed (AA) ColonView (CV) quick test; a new-generation fecal immunochemical test (FIT) for hemoglobin (Hb) and hemoglobin/haptoglobin (Hb/Hp) (Biohit Oyj, Helsi...

Methemoglobinemia Workup
https://emedicine.medscape.com/article/204178-workup

Nov 5th, 2021 - Laboratory Studies Investigations to rule out hemolysis (complete blood count [CBC], reticulocyte count, peripheral smear review, lactate dehydrogenase [LDH], bilirubin, haptoglobin and Heinz body preparation) and end-organ dysfunction or failure ...

Methemoglobinemia Workup
http://emedicine.medscape.com/article/204178-workup

Nov 5th, 2021 - Laboratory Studies Investigations to rule out hemolysis (complete blood count [CBC], reticulocyte count, peripheral smear review, lactate dehydrogenase [LDH], bilirubin, haptoglobin and Heinz body preparation) and end-organ dysfunction or failure ...

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Clinicaltrials.gov  21 results

Transcatheter Para-Valvular Leak Closure: An International Prospective Multicentre Registry
https://clinicaltrials.gov/ct2/show/NCT05089136

Nov 19th, 2021 - Prosthetic paravalvular leaks (PVL) are associated with congestive heart failure and haemolysis, for which the standard treatment is open-heart surgery with the attendant risks to the patient. Transcatheter closure has emerged as an alternative. P...

A Study With Iron Sucrose in Healthy Volunteers and Chronic Kidney Disease Stage 3-4 Subjects
https://clinicaltrials.gov/ct2/show/NCT04072432

Oct 6th, 2021 - This is a Phase 1b single-center, dose-escalating study to evaluate the pharmacodynamic effect of FeS in healthy volunteers and in subjects with stage 3-4 CKD. The following biomarkers will be used as surrogate measures of protective activity: Hap...

The Impact of Age-dependent Haptoglobin Deficiency on Plasma Free Hemoglobin Levels During Extracorporeal Membrane Oxygenation Support
https://clinicaltrials.gov/ct2/show/NCT03472768

Jan 14th, 2021 - Newborns and children with life-threatening heart and lung failure may require support with ECMO (extracorporeal membrane oxygenation). With ECMO, oxygen and carbon dioxide are exchanged and circulated throughout the body even if the heart is unab...

RBT-1 Phase 1b Clinical Trial in Healthy Volunteers and Subjects With CKD
https://clinicaltrials.gov/ct2/show/NCT03630029

May 11th, 2020 - This is a Phase 1b, single-center, dose-escalating study to evaluate the safety, tolerability, and pharmacodynamic effect of RBT-1 in healthy volunteers and in subjects with stage 3b-4 CKD. The following biomarkers will be used as surrogate measur...

Blood Flow Effects on Silicon Substrates
https://clinicaltrials.gov/ct2/show/NCT03241667

Feb 28th, 2020 - For patient safety, the investigators will measure the following labs: Blood tests (routine safety and frequency). CBC/platelets: q 1 hr, at HD next day ABGs, including lactate: Q 1 hr x 6 Na, K, Cl, Bicarb, BUN, Creatinine, Ca, ionized Ca, Mg, Ph...

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News  26 results

Evans’ Syndrome in Undiagnosed Small Lymphocytic Lymphoma: Case Report and Literature Review
https://www.mdedge.com/fedprac/avaho/article/245949/lymphoma-plasma-cell-disorders/evans-syndrome-undiagnosed-small
Faith Opeyemi Abodunrin ([email protected]), Abubakar Tauseef

Sep 10th, 2021 - Background Evans’ syndrome is a rare entity characterized by concomitant or sequential multilineage cytopenia particularly autoimmune hemolytic anemia, ITP and very rarely autoimmune neutropenia. Although more common in young adults, it can occur.

Transplant-Associated Thrombotic Microangiopathy: New Insights, Emerging Treatments
https://www.onclive.com/view/transplant-associated-thrombotic-microangiopathy-new-insights-emerging-treatments

Jul 22nd, 2021 - Transplant-associated thrombotic microangiopathy (TA-TMA) is a complication of stem cell transplants that can occur with peripherally mobilized stem cells or bone marrow-derived stem cells. TA-TMA remains a difficult complication to address, with ...

FDA Extends Review Period for Narsoplimab for HSCT-TMA
https://www.onclive.com/view/fda-extends-review-period-for-narsoplimab-for-hsct-tma

May 21st, 2021 - The FDA has announced that it will need more time to review the biologics license application (BLA) for narsoplimab as a potential therapeutic option in patients with hematopoietic stem cell transplant–associated thrombotic microangiopathy (HSCT-T...

Diagnosis and Management of Kidney Injury Following HSCT Refined
https://www.onclive.com/view/diagnosis-and-management-of-kidney-injury-following-hsct-refined

Dec 4th, 2020 - Sangeeta R. Hingorani, MD, MPH Kidney complications often occur following successful hematopoietic stem cell transplantation (HSCT) from a myriad of underlying etiologies, according to up-to-date information provided during an educational session...

Expert Provides Guidelines for Diagnosis and Management of TA-TMA
https://www.onclive.com/view/expert-provides-guidelines-for-diagnosis-and-management-of-ta-tma

Dec 4th, 2020 - Sonata Jodele, MD While complex, criteria for diagnosing transplant-associated thrombotic microangiopathy (TA-TMA) following hematopoietic stem cell transplantation (HSCT) should be closely followed and should begin with screening, according to a...

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