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About 2,373 results

ALLMedicine™ Transferrin Receptor Center

Research & Reviews  882 results

The Effect of Human Milk Oligosaccharides and Galacto-oligosaccharides on Iron Absorption in Kenyan Infants
https://clinicaltrials.gov/ct2/show/NCT04163406

Jun 23rd, 2022 - Iron absorption from differently labelled iron-fortified maize-based test meals will be measured in 55 infants. At baseline a venipuncture blood sample will be collected from all infants for the determination of the following iron and inflammation...

Screening for Biomarkers Associated with Left Ventricular Function During Follow-up Aft...
https://doi.org/10.1007/s12265-022-10285-2 10.1093/eurheartj/ehw128 10.1161/01.CIR.66.3.527 10.7326/0003-4819-134-6-200103200-00009 10.1016/j.jacc.2008.08.067 10.1016/j.jchf.2014.10.007 10.1038/nrm2970 10.2174/1566524033361537 10.1007/s11897-010-0044-2 10.1152/physrev.00012.2007 10.1016/j.jacc.2016.01.073 10.1161/01.RES.0000261924.76669.36 10.1038/nm1574 10.1002/ejhf.431 10.1016/j.cardfail.2015.07.017 10.2217/bmm.15.12 10.1002/ejhf.980 10.1111/jch.12849 10.1161/hc0102.101396 10.1093/ehjci/jex260 10.1136/heartjnl-2014-305538 10.1080/03009734.2017.1407849 10.1016/j.thromres.2018.10.011 10.1093/eurheartj/ehy421 10.1371/journal.pone.0095192 10.1093/ehjci/jev014 10.1093/ehjci/jeu184 10.1002/sim.4067 10.1002/ejhf.754 10.1016/j.lfs.2014.09.014 10.1161/01.HYP.33.2.663 10.1016/S1388-9842(01)00237-9 10.1161/CIRCHEARTFAILURE.107.746172 10.1016/j.lab.2004.08.007 10.1002/jcp.28820 10.1016/j.cardiores.2006.02.025 10.1093/eurheartj/ehu235 10.1007/s00395-020-0782-6 10.1093/ehjci/jey101 10.1016/j.ijcard.2011.08.006 10.1007/s11427-016-0131-4 10.1093/eurheartj/ehz680 10.1002/ejhf.49 10.1182/blood-2002-03-0778 10.1016/j.jchf.2016.12.008 10.1055/s-0039-1696973 10.1160/TH16-08-0600 10.1016/j.ijcard.2018.07.130 10.1038/nm.3284 10.1016/j.jacc.2012.08.1003 10.1111/1440-1681.13048
Journal of Cardiovascular Translational Research; Christersson C, Baron T et. al.

Jun 22nd, 2022 - A proportion of patients with the acute coronary syndrome (ACS) will suffer progressive remodeling of the left ventricular (LV). The aim was to screen for important biomarkers from a large-scale protein profiling in 420 ACS patients and define bio...

Secondary ferroptosis promotes thrombogenesis after venous injury in rats.
https://doi.org/10.1016/j.thromres.2022.06.002
Thrombosis Research; Ma H, Yan X et. al.

Jun 20th, 2022 - Iron accumulation significantly accelerates thrombosis after vascular injury. The role of the ferroptosis pathway induced by iron overload in thrombosis has not been previously elucidated. In this study, we answer certain obscure questions regardi...

Transferrin receptor-mediated liposomal drug delivery: recent trends in targeted therap...
https://doi.org/10.1080/17425247.2022.2083106
Expert Opinion on Drug Delivery; Mojarad-Jabali S, Mahdinloo S et. al.

Jun 15th, 2022 - Compared to normal cells, malignant cancer cells require more iron for their growth and rapid proliferation, which can be supplied by a high expression level of transferrin receptor (TfR). It is well known that the expression of TfR on the tumor c...

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Guidelines  1 results

EASL clinical practice guidelines for HFE hemochromatosis.
https://doi.org/10.1016/j.jhep.2010.03.001
Journal of Hepatology;

May 18th, 2010 - Iron overload in humans is associated with a variety of genetic and acquired conditions. Of these, HFE hemochromatosis (HFE-HC) is by far the most frequent and most well-defined inherited cause when considering epidemiological aspects and risks fo...

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Clinicaltrials.gov  56 results

The Effect of Human Milk Oligosaccharides and Galacto-oligosaccharides on Iron Absorption in Kenyan Infants
https://clinicaltrials.gov/ct2/show/NCT04163406

Jun 23rd, 2022 - Iron absorption from differently labelled iron-fortified maize-based test meals will be measured in 55 infants. At baseline a venipuncture blood sample will be collected from all infants for the determination of the following iron and inflammation...

Effects of Replacing Red Meat With Legumes on Biomarkers of Chronic Diseases in Healthy Men (Leg4Life)
https://clinicaltrials.gov/ct2/show/NCT04599920

May 18th, 2022 - A human intervention study with healthy volunteers will be carried out to investigate the effects of partial replacement of red meat with legume-based foods on gut metabolism and markers for colorectal cancer as well as biomarkers for cardiovascul...

Anemia in Patients With Endocarditis
https://clinicaltrials.gov/ct2/show/NCT04840225

Apr 26th, 2022 - Anemia is an adverse prognostic marker in both cardiac diseases and infectious diseases. In patients with bacterial endocarditis (IE), anemia has a prevalence of 55-80%. In a sub-study to our POET I trial (RCT with 400 patients with IE, published ...

Intravenous Iron Infusion on Chemotherapy-induced Anemia
https://clinicaltrials.gov/ct2/show/NCT05299411

Mar 29th, 2022 - FOLFOX, the first-line regimen based on 5-FU and oxaliplatin, is adjuvant chemotherapy for pathologic stage II/III colorectal cancer patients. Among various side effects of FOLFOX, chemotherapy-induced anemia occurs in about 30% of patients with F...

Determinants of Neonatal Anemia in Women Carrying Multiples
https://clinicaltrials.gov/ct2/show/NCT01582802

Mar 25th, 2022 - Pregnant women (n=100-125) carrying multiples (twins and triplets) will be identified when entering prenatal care. Women will be invited to participate in a longitudinal study of Fe homeostasis across pregnancy and at delivery in the maternal / ne...

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News  10 results

CD71-Directed Probody-Drug Conjugate Shows Safety, Signals of Activity in Advanced Solid Tumors
https://www.onclive.com/view/cd71directed-probodydrug-conjugate-shows-safety-signals-of-activity-in-advanced-solid-tumors

Dec 20th, 2020 - Melissa Johnson, MD The CD71-directed probody-drug conjugate (PDC) of monomethyl auristatin E (MMAE) CX-2029 showed tolerability and antitumor activity in patients with advanced cancer, according to findings from the first-in-human phase 1/2 PROC...

Gene plays key role in iron homeostasis
https://www.mdedge.com/hematology-oncology/article/185638/anemia/gene-plays-key-role-iron-homeostasis
HT Staff

Jun 1st, 2017 - Red blood cells A gene known to prevent autoimmune diseases is a key regulator in iron uptake, according to research published in Cell Reports. “We found previously that, when mice lack the gene Regnase-1, they suffer from severe autoimmune diseas.

Iron deficiency may explain persistent hypothyroidism symptoms
https://www.mdedge.com/endocrinology/article/104350/pituitary-thyroid-adrenal-disorders/iron-deficiency-may-explain
Sharon Worcester

Nov 12th, 2015 - LAKE BUENA VISTA, FLA. – Between 30% and 50% of hypothyroid patients with persistent symptoms despite adequate levothyroxine therapy may have covert iron deficiency, findings from a small study suggest.

Hemochromatosis: More Common Than You Think?
https://www.medscape.com/viewarticle/772578_1

Oct 22nd, 2012 - Hereditary HFE Hemochromatosis Hereditary HFE hemochromatosis accounts for most cases of excess body iron that result from increased iron absorption. Clinical disease in HFE hemochromatosis has variable penetrance; women are less likely to develop...

Hemochromatosis: More Common Than You Think?
https://www.medscape.com/viewarticle/772578_3

Oct 22nd, 2012 - Screening and Diagnosis of Hemochromatosis At the present time, screening of all patients for hemochromatosis is not recommended. However, patients with liver disease and those who have a positive family history, suggestive symptoms, or abnormal i...

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