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About 901 results

ALLMedicine™ Aldolase Center

Research & Reviews  447 results

Sucrose Toxicity in Infants.
https://doi.org/10.1002/hep.31669
Hepatology (Baltimore, Md.); Moon JH, Stormon MO

Dec 5th, 2020 - Hereditary fructose intolerance (HFI) is an autosomal recessive disorder caused by mutation in the ALDOB gene, which leads to aldolase B deficiency. Fructose ingestion results in accumulation of substrates fructose 1-phosphate and fructose 1,6-bip...

The melanoma brain metastatic microenvironment: aldolase C partakes in shaping the mali...
https://doi.org/10.1002/1878-0261.12872
Molecular Oncology References; Izraely S, Ben-Menachem S et. al.

Dec 4th, 2020 - Previous studies indicated that microglia cells upregulate the expression of aldolase C (ALDOC) in melanoma cells. The present study using brain-metastasizing variants from three human melanomas explores the functional role of ALDOC in the formati...

Design of Epitope-Based Peptide Vaccine against Pseudomonas aeruginosa Fructose Bisphos...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666636
Journal of Immunology Research; Elhag M, Alaagib RM et. al.

Nov 18th, 2020 - Pseudomonas aeruginosa is a common pathogen that is responsible for serious hospital-acquired infections, ventilator-associated pneumonia, and various sepsis syndromes. Also, it is a multidrug-resistant pathogen recognized for its ubiquity and its...

Aldolase deployed for surveilling glucose.
https://doi.org/10.1038/s41580-020-00305-x
Nature Reviews. Molecular Cell Biology; Lin SC

Oct 16th, 2020 - Aldolase deployed for surveilling glucose.|2020|Lin SC,|

Hereditary Fructose Intolerance Diagnosed in Adulthood.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817925
Gut and Liver; Kim MS, Moon JS et. al.

Oct 8th, 2020 - Hereditary fructose intolerance (HFI) is an autosomal recessive disorder caused by a mutation in the aldolase B gene. HFI patients exhibit nausea, vomiting, abdominal pain, hypoglycemia, and elevated liver enzymes after dietary fructose exposure. ...

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Clinicaltrials.gov  451 results

Sucrose Toxicity in Infants.
https://doi.org/10.1002/hep.31669
Hepatology (Baltimore, Md.); Moon JH, Stormon MO

Dec 5th, 2020 - Hereditary fructose intolerance (HFI) is an autosomal recessive disorder caused by mutation in the ALDOB gene, which leads to aldolase B deficiency. Fructose ingestion results in accumulation of substrates fructose 1-phosphate and fructose 1,6-bip...

The melanoma brain metastatic microenvironment: aldolase C partakes in shaping the mali...
https://doi.org/10.1002/1878-0261.12872
Molecular Oncology References; Izraely S, Ben-Menachem S et. al.

Dec 4th, 2020 - Previous studies indicated that microglia cells upregulate the expression of aldolase C (ALDOC) in melanoma cells. The present study using brain-metastasizing variants from three human melanomas explores the functional role of ALDOC in the formati...

Design of Epitope-Based Peptide Vaccine against Pseudomonas aeruginosa Fructose Bisphos...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666636
Journal of Immunology Research; Elhag M, Alaagib RM et. al.

Nov 18th, 2020 - Pseudomonas aeruginosa is a common pathogen that is responsible for serious hospital-acquired infections, ventilator-associated pneumonia, and various sepsis syndromes. Also, it is a multidrug-resistant pathogen recognized for its ubiquity and its...

Aldolase deployed for surveilling glucose.
https://doi.org/10.1038/s41580-020-00305-x
Nature Reviews. Molecular Cell Biology; Lin SC

Oct 16th, 2020 - Aldolase deployed for surveilling glucose.|2020|Lin SC,|

Hereditary Fructose Intolerance Diagnosed in Adulthood.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817925
Gut and Liver; Kim MS, Moon JS et. al.

Oct 8th, 2020 - Hereditary fructose intolerance (HFI) is an autosomal recessive disorder caused by a mutation in the aldolase B gene. HFI patients exhibit nausea, vomiting, abdominal pain, hypoglycemia, and elevated liver enzymes after dietary fructose exposure. ...

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News  2 results

Amyopathic Dermatomyositis With Plantar Keratoderma Responding to Methotrexate Therapy
https://www.mdedge.com/dermatology/article/145236/rare-diseases/amyopathic-dermatomyositis-plantar-keratoderma-responding/page/0/1

Aug 24th, 2017 - Comment Amyopathic DM is a subset of DM that accounts for 10% to 20% of DM cases. 1,2 Sontheimer’s3 diagnostic criteria for ADM require histopathologic confirmation of the hallmark skin findings of classic DM and lack of muscle weakness or muscle e.

CPG Sec. 400.335 Fructose-Containing Drugs
http://www.fda.gov/regulatory-information/search-fda-guidance-documents/cpg-sec-400335-fructose-containing-drugs

Issued by: Guidance Issuing Office Office of Regulatory Affairs BACKGROUND: Hereditary fructose intolerance is a metabolic error due to the deficiency of fructose 1-phosphate aldolase in the liver. It is thought to be inherited as an autosomal rec...

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Patient Education  1 results see all →