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About 6,367 results

ALLMedicine Creatinine Clearance Center

Research & Reviews  2,935 results

A simple scoring method to predict augmented renal clearance in haematologic malignancies.
https://doi.org/10.1111/jcpt.13193
Journal of Clinical Pharmacy and Therapeutics REFERENCES; Saito K, Kamio S et. al.

Jun 4th, 2020 - Augmented renal clearance (ARC; hyperfiltration with over 130 mL/min/1.73 m2 of creatinine clearance (CLcr )) commonly occurs in critically ill patients. Recent reports indicate that ARC also occurs in haematologic malignancies. However, the risk ...

An open-label, pharmacokinetic study of lenalidomide and dexamethasone therapy in previ...
https://doi.org/10.1080/10428194.2020.1747064
Leukemia & Lymphoma; Chen CI, Cao Y et. al.

May 30th, 2020 - Lenalidomide is a backbone agent in the treatment of multiple myeloma, but dose adjustment is required for those with renal impairment (RI). We evaluated the pharmacokinetics (PK) and safety of lenalidomide and dexamethasone as frontline pre-trans...

Salidroside protects against Diabetes Mellitus-induced kidney injury and renal fibrosis...
https://doi.org/10.1111/1440-1681.13355
Clinical and Experimental Pharmacology & Physiology; Shati AA, Alfaifi MY et. al.

May 29th, 2020 - This study evaluated if the nephroprotective effect of Salidroside in type 1 diabetes mellitus (T1DM) involves modulation of Wnt/β-catenin signaling pathways. Control or Streptozotocin (STZ, 50 mg/kg, i.v.)-induced T1DM adult male Wister rats were...

Outcomes associated with apixaban vs warfarin in patients with renal dysfunction.
https://doi.org/10.1182/bloodadvances.2019000972
Blood Advances; Hanni C, Petrovitch E et. al.

May 28th, 2020 - Apixaban in patients with impaired renal function is supported by limited data. Landmark clinical trials evaluating apixaban in patients with atrial fibrillation and/or acute venous thromboembolism excluded patients with creatinine clearance (CrCl...

Kolliphor® HS 15-Cyclodextrin Complex for the Delivery of Voriconazole: Preparation, Ch...
https://doi.org/10.2174/1389200221666200520085915
Current Drug Metabolism; Li Y, Zhu C et. al.

May 20th, 2020 - This study aimed to reduce the amount of sulfobutylether-β-cyclodextrin (SBECD) used in the marketed voriconazole injections to meet the clinical needs of patients with moderateto-severe renal impairment (creatinine clearance rate < 50 mL/min). Th...

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Guidelines  1 results

KDIGO 2012 Clinical Practice Guideline CKD classification rules out creatinine clearanc...
https://doi.org/10.1016/j.clinbiochem.2015.07.030
Clinical Biochemistry; Ognibene A, Grandi G et. al.

Aug 1st, 2015 - The recent guideline for the evaluation and management of Chronic Kidney Disease recommends assessing GFR employing equations based on serum creatinine; despite this, creatinine clearance 24-hour urine collection is used routinely in many settings...

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Drugs  51 results see all →

Clinicaltrials.gov  3,175 results

A simple scoring method to predict augmented renal clearance in haematologic malignancies.
https://doi.org/10.1111/jcpt.13193
Journal of Clinical Pharmacy and Therapeutics REFERENCES; Saito K, Kamio S et. al.

Jun 4th, 2020 - Augmented renal clearance (ARC; hyperfiltration with over 130 mL/min/1.73 m2 of creatinine clearance (CLcr )) commonly occurs in critically ill patients. Recent reports indicate that ARC also occurs in haematologic malignancies. However, the risk ...

An open-label, pharmacokinetic study of lenalidomide and dexamethasone therapy in previ...
https://doi.org/10.1080/10428194.2020.1747064
Leukemia & Lymphoma; Chen CI, Cao Y et. al.

May 30th, 2020 - Lenalidomide is a backbone agent in the treatment of multiple myeloma, but dose adjustment is required for those with renal impairment (RI). We evaluated the pharmacokinetics (PK) and safety of lenalidomide and dexamethasone as frontline pre-trans...

Salidroside protects against Diabetes Mellitus-induced kidney injury and renal fibrosis...
https://doi.org/10.1111/1440-1681.13355
Clinical and Experimental Pharmacology & Physiology; Shati AA, Alfaifi MY et. al.

May 29th, 2020 - This study evaluated if the nephroprotective effect of Salidroside in type 1 diabetes mellitus (T1DM) involves modulation of Wnt/β-catenin signaling pathways. Control or Streptozotocin (STZ, 50 mg/kg, i.v.)-induced T1DM adult male Wister rats were...

Outcomes associated with apixaban vs warfarin in patients with renal dysfunction.
https://doi.org/10.1182/bloodadvances.2019000972
Blood Advances; Hanni C, Petrovitch E et. al.

May 28th, 2020 - Apixaban in patients with impaired renal function is supported by limited data. Landmark clinical trials evaluating apixaban in patients with atrial fibrillation and/or acute venous thromboembolism excluded patients with creatinine clearance (CrCl...

Calcitriol - calcitriol capsule, liquid filled-Bryant Ranch Prepack
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7e0574e0-3a41-486a-be37-92ab56b7f81f

May 21st, 2020 - Calcitriol is indicated in the management of secondary hyperparathyroidism and resultant metabolic bone disease in patients with moderate to severe chronic renal failure (Ccr 15 to 55 mL/min) not yet on dialysis. In children, the creatinine cleara...

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News  205 results

Cath Lab Recap: 'Ultra-Low' Contrast for PCI; Stroke Tx Reperfusion Overestimated
https://www.medpagetoday.com/cardiology/pci/74854

Aug 29th, 2018 - Percutaneous coronary intervention can be performed with "ultra-low" contrast volume -- less than or equal to the patient's estimated creatinine clearance -- when the individual is at high risk of acute kidney injury. (Catheterization and Cardiova...

How to choose between highly effective HBV therapies
https://www.mdedge.com/familymedicine/article/166121/infectious-diseases/how-choose-between-highly-effective-hbv-therapies/page/0/3
Internal Medicine News;

May 19th, 2018 - Conversely, entecavir, an older and less expensive drug than TAF, deserves priority in a patient with no prior exposure to a nucleoside, no HIV coinfection, or in an individual with a creatinine clearance below 15 mL/min after dose adjustment. TAF.

Management of Patients with HIV and Hepatitis B Coinfection
https://www.mdedge.com/jcomjournal/article/149688/infectious-diseases/management-patients-hiv-and-hepatitis-b-coinfection/page/0/3

Oct 18th, 2017 - • When should HBV treatment be started in patients with coinfection? An ART regimen containing TDF (creatinine clearance > 50 mL/min) or TAF (creatinine clearance > 30 mL/min) with lamivudine or emtricitabine should be used in all HIV/HBV patients.

Higher Allopurinol Dose Can Safely Lower SU in Gout
https://www.medpagetoday.com/rheumatology/generalrheumatology/64322

Apr 4th, 2017 - Action Points Higher than creatinine clearance (CrCL)-based doses of allopurinol can effectively lower serum urate (SU) levels to treatment target in most people with gout, and the allopurinol dose escalation is well tolerated. Recognize that whil...

More Frequent Creatinine Checks for Some Patients on Oral Anticoagulation?
https://www.medscape.com/viewarticle/873113

Dec 8th, 2016 - BOSTON, MA — Among patients on long-term warfarin therapy seen in an anticoagulation clinic, those with CAD or moderate renal impairment when therapy was started were most likely to develop severe renal impairment—defined as creatinine clearance (...

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