About 635 results

ALLMedicine™ Aldolase Center

Research & Reviews  247 results

Climbing fiber-mediated spillover transmission to interneurons is regulated by EAAT4.
The Journal of Neuroscience : the Official Journal of The... Malhotra S, Banumurthy G et. al.

Aug 18th, 2021 - Neurotransmitter spillover is a form of communication not readily predicted by anatomical structure. In the cerebellum, glutamate spillover from climbing fibers recruits molecular layer interneurons in the absence of conventional synaptic connecti...

Homocitrullination of lysine residues mediated by myeloid-derived suppressor cells in t...
Journal for Immunotherapy of Cancer; Cook KW, Xue W et. al.

Jul 30th, 2021 - Homocitrullination is the post-translational modification of lysine that is recognized by T cells. This study identified homocitrullinated peptides from aldolase, enolase, cytokeratin and binding immunoglobulin protein and used human leukocyte ant...

Fructose-1,6-Bisphosphate Aldolase B Depletion Promotes Hepatocellular Carcinogenesis T...
Hepatology (Baltimore, Md.); Liu G, Wang N et. al.

Jul 23rd, 2021 - Insulin receptor (IR) transduces cell surface signal through phosphoinositide 3-kinase (PI3K)-AKT pathways or translocates to the nucleus and binds to the promoters to regulate genes associated with insulin actions, including de novo lipogenesis (...

Primary Hyperoxaluria Type 3 Can Also Result in Kidney Failure: A Case Report.
American Journal of Kidney Diseases : the Official Journa... Singh P, Granberg CF et. al.

Jul 11th, 2021 - Primary hyperoxaluria (PH) is a group of genetic disorders that result in an increased hepatic production of oxalate. PH type 3 (PH3) is the most recently identified subtype and results from mutations in the mitochondrial 4-hydroxy-2-oxoglutarate ...

The moonlighting protein fructose 1,6-bisphosphate aldolase as a potential vaccine cand...
Developmental and Comparative Immunology; Pham TH, Rao S et. al.

Jun 30th, 2021 - Vaccination is the most effective, safe, and environmentally friendly method to prevent the outbreak of Photobacterium damselae subsp. piscicida (Phdp), a dangerous pathogen in aquaculture worldwide. Here, recombinant proteins of catalase, superox...

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News  7 results

Anti-TIF1-Ab-Positive Dermatomyositis Linked to Higher Cancer Risk

Dec 13th, 2018 - Action Points Anti-TNF1-Ab positive dermatomyositis (DM) is linked to an elevated risk of cancer, especially ovarian cancer. This risk is present approximately 3 years on either side of DM onset. The link between DM and cancer is present for patie...

Gottron Papules Mimicking Dermatomyositis: An Unusual Manifestation of Systemic Lupus Erythematosus
Ji Won Ahn, MD, Sherry Yang, MD et. al.

Jul 26th, 2018 - To the Editor: An 11-year-old girl presented to the dermatology clinic with an asymptomatic rash on the bilateral forearms, dorsal hands, and ears of 1 month’s duration. Recent history was notable for persistent low-grade fevers, dizziness, headac.

Amyopathic Dermatomyositis With Plantar Keratoderma Responding to Methotrexate Therapy

Aug 24th, 2017 - Comment Amyopathic DM is a subset of DM that accounts for 10% to 20% of DM cases. 1,2 Sontheimer’s3 diagnostic criteria for ADM require histopathologic confirmation of the hallmark skin findings of classic DM and lack of muscle weakness or muscle e.

CPG Sec. 400.335 Fructose-Containing Drugs

Issued by: Guidance Issuing Office Office of Regulatory Affairs BACKGROUND: Hereditary fructose intolerance is a metabolic error due to the deficiency of fructose 1-phosphate aldolase in the liver. It is thought to be inherited as an autosomal rec...

Widespread Poikilodermatous Dermatomyositis Associated With Chronic Lymphocytic Leukemia
Daniel J. Ventarola, MD, Paul C. Contard, MD, PhD et. al.

Feb 8th, 2017 - To the Editor: Dermatomyositis represents a rare idiopathic inflammatory process presenting with cutaneous lesions and muscular weakness. It often represents a paraneoplastic syndrome.

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