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About 890 results

ALLMedicine™ Aldolase Center

Research & Reviews  332 results

Biochemical and Chemical Myopathy as Isolated Initial Manifestation of a Mitochondrial ...
https://doi.org/10.1097/CND.0000000000000406
Journal of Clinical Neuromuscular Disease; Finsterer J

Nov 22nd, 2022 - Isolated and asymptomatic elevation of creatine kinase (hyper-CKemia) can be one of the initial manifestations of a mitochondrial disorder (MID). We present an asymptomatic patient with accidently detected isolated hyper-CKemia and respiratory cha...

Unexpected false-negative result in a traveller's malaria diagnosis.
https://doi.org/10.1093/jtm/taac124
Journal of Travel Medicine; Perez-Ugarte A, Maturana CR et. al.

Oct 28th, 2022 - A four-year-old traveller returned from Senegal with symptoms compatible with malaria. Plasmodium falciparum HRP-2 antigen detection was negative while panmalarial aldolase was positive. Microscopy confirmed the presence of P. falciparum trophozoi...

Polybrominated diphenyl ethers interact with the key protein involved in carbohydrate m...
https://doi.org/10.1016/j.envpol.2022.120466
Environmental Pollution (Barking, Essex : 1987); Liu Q, Liu N et. al.

Oct 21st, 2022 - Rice exposed to organic pollutants such as polybrominated diphenyl ethers (PBDEs) usually experiences reduced biomass and increased soluble sugar content. This study showed that 2, 2', 4, 4'-tetrabromodiphenyl ether (BDE-47) led to increased gluco...

Eosinophilic Fasciitis Workup
https://emedicine.medscape.com/article/329515-workup

Oct 10th, 2022 - Laboratory Studies Characteristic laboratory findings of eosinophilic fasciitis (EF) include the following: Peripheral blood eosinophilia is present in 61%-83% of patients. The degree of eosinophilia is variable over time, even in the absence of s...

Self-assembling protein nanoparticles and virus like particles correctly display β-barr...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9480994
PloS One; Cappelli L, Cinelli P et. al.

Sep 17th, 2022 - Recombinant protein-based vaccines are a valid and safer alternative to traditional vaccines based on live-attenuated or killed pathogens. However, the immune response of subunit vaccines is generally lower compared to that elicited by traditional...

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Clinicaltrials.gov  7 results

Combined Antioxidant Therapy on Oxidative Stress, Mitochondrial Dysfunction Markers in Diabetic Retinopathy
https://clinicaltrials.gov/ct2/show/NCT03702374

Apr 1st, 2022 - Diabetic retinopathy is a diabetes microvascular complication due to an insufficient oxygen supply to its endothelial cells in states of constant hyperglycemia. This entity is classified in two main categories: non-proliferative diabetic retinopat...

Evaluating Safety & Efficacy of Apremilast in the Treatment of Cutaneous Disease in Patients With Recalcitrant Dermatomyositis
https://clinicaltrials.gov/ct2/show/NCT03529955

Jul 8th, 2021 - Sponsor Name (PI): Carole Bitar, MD Sub-PI: Erin Boh, MD, PhD; Brittany Stumpf, MD; Collaborator: Nakhle Saba, MD # of Participants Sites: 1, Tulane University 4: Participant Countries: United States II. PRODUCT INFORMATION Study Title: A phase 2,...

Defining Normal Postoperative Magnetic Resonance Imaging After Total Knee Arthroplasty
https://clinicaltrials.gov/ct2/show/NCT04821245

May 25th, 2021 - In 2016, 3 sentinel cases of presumed local anesthetic-induced myotoxicity were reported after TKA with associated continuous adductor canal block (CACB) analgesia. The diagnosis was made based on its consistency with animal and human descriptions...

Fructose Supplementation in Carriers for Hereditary Fructose Intolerance
https://clinicaltrials.gov/ct2/show/NCT03545581

Apr 22nd, 2019 - A high fructose intake also increases blood lactate and uric acid concentrations. It has been proposed that uric acid may contribute to insulin resistance by impairing endothelium-dependent vasodilation, promoting pro-inflammatory effects and dysl...

Validation of RealAmp Method for the Diagnosis of Malaria in Endemic Areas of Brazil
https://clinicaltrials.gov/ct2/show/NCT02371395

Oct 23rd, 2018 - Worldwide, approximately 2 billion people live in areas at risk for malaria with morbidity surpassing 250 million cases, with approximately 800,000 deaths, per year. Of the four species of malaria parasites that cause human infection, P. falciparu...

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News  17 results

Sometimes You Can’t Blame the Sun
https://www.mdedge.com/clinicianreviews/article/250758/womens-health/sometimes-you-cant-blame-sun
Joe R. Monroe, MPAS, PA

Jan 14th, 2022 - ANSWER The correct answer is all of the above (choice “e”). DISCUSSION Most cases of dermatomyositis, which the patient’s presentation and lab results suggested, require nerve conduction studies, a check of serum aldolase levels, and skin and musc.

Verrucous Scalp Plaque and Widespread Eruption
https://www.mdedge.com/dermatology/article/245017/dermatopathology/verrucous-scalp-plaque-and-widespread-eruption
Lauren L. Beal, BA, James Robert Duncan, MD et. al.

Aug 31st, 2021 - The Diagnosis: Pemphigus Foliaceous Laboratory workup including a complete blood cell count with differential, comprehensive metabolic panel, antinuclear antibodies, Sjögren syndrome A and B antibodies, hepatitis profile, rapid plasma reagin, HIV.

Persistent Panniculitis in Dermatomyositis
https://www.mdedge.com/dermatology/article/243864/rare-diseases/persistent-panniculitis-dermatomyositis
Kayla M. Babbush, MD, Ranon E. Mann, MD et. al.

Aug 3rd, 2021 - To the Editor: A 62-year-old woman with a history of dermatomyositis (DM) presented to dermatology clinic for evaluation of multiple subcutaneous nodules. Two years prior to the current presentation, the patient was diagnosed by her primary care p.

The Use of Autoantibody Testing in a Postpartum Patient at Risk for Malignancy-Associated Dermatomyositis
https://www.medscape.com/viewarticle/950202

May 4th, 2021 - This article originally appeared on the Hospital for Special Surgery website. Case Report In May 2019, a 32-year-old woman developed a rash on her face, chest, and knuckles, initially thought to be contact dermatitis. She saw a second dermatologis...

Myositis mimics: Clues for making the right diagnosis
https://www.mdedge.com/rheumatology/article/195405/lupus-connective-tissue-diseases/myositis-mimics-clues-making-right
Sharon Worcester

Feb 28th, 2019 - A number of conditions can mimic myositis, but clues that can point to the correct diagnosis are often present in cases involving the mimics, according to Lisa Christopher-Stine, MD. Dr.

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