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ALLMedicine™ Aldolase Center

Research & Reviews  271 results

Sometimes You Can’t Blame the Sun
https://www.mdedge.com/clinicianreviews/article/250758/womens-health/sometimes-you-cant-blame-sun
Joe R. Monroe, MPAS, PA

Jan 14th, 2022 - ANSWER The correct answer is all of the above (choice “e”). DISCUSSION Most cases of dermatomyositis, which the patient’s presentation and lab results suggested, require nerve conduction studies, a check of serum aldolase levels, and skin and musc.

The POU2F1-ALDOA axis promotes the proliferation and chemoresistance of colon cancer ce...
https://doi.org/10.1038/s41388-021-02148-y
Oncogene Lin J, Xia L et. al.

Jan 9th, 2022 - Cancer metabolic reprogramming enhances its malignant behaviors and drug resistance, which is regulated by POU domain transcription factors. This study explored the effect of POU domain class 2 transcription factor 1 (POU2F1) on metabolic reprogra...

Schwartz-Jampel Syndrome
http://emedicine.medscape.com/article/1172013-overview

Jan 6th, 2022 - Background Schwartz-Jampel syndrome (SJS) is a term now applied to 2 different inherited, autosomal recessive conditions, sometimes termed SJS type I and SJS type II. Both are very rare. SJS type I has 2 recognized subtypes, IA and IB, which are s...

Muscular sarcoidosis in the eyes of 18 F-FDG PET/CT.
https://doi.org/10.1002/jcu.23120
Journal of Clinical Ultrasound : JCU; Milojevic IG, Sobic-Saranovic D et. al.

Dec 25th, 2021 - The aim of this study was to determine the frequency, symptoms, activity and pattern of muscle sarcoidosis, correlation with laboratory parameters, and to assess its therapy response with 18 F-FDG PET/CT. Study included 90 patients with biopsy con...

A cryo-electron microscopy support film formed by 2D crystals of hydrophobin HFBI.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671466
Nature Communications; Fan H, Wang B et. al.

Dec 16th, 2021 - Cryo-electron microscopy (cryo-EM) has become a powerful tool to resolve high-resolution structures of biomacromolecules in solution. However, air-water interface induced preferred orientations, dissociation or denaturation of biomacromolecules du...

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Clinicaltrials.gov  1 results

Evaluating Safety & Efficacy of Apremilast in the Treatment of Cutaneous Disease in Patients With Recalcitrant Dermatomyositis
https://clinicaltrials.gov/ct2/show/NCT03529955

Jul 8th, 2021 - Sponsor Name (PI): Carole Bitar, MD Sub-PI: Erin Boh, MD, PhD; Brittany Stumpf, MD; Collaborator: Nakhle Saba, MD # of Participants Sites: 1, Tulane University 4: Participant Countries: United States II. PRODUCT INFORMATION Study Title: A phase 2,...

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News  10 results

Sometimes You Can’t Blame the Sun
https://www.mdedge.com/clinicianreviews/article/250758/womens-health/sometimes-you-cant-blame-sun
Joe R. Monroe, MPAS, PA

Jan 14th, 2022 - ANSWER The correct answer is all of the above (choice “e”). DISCUSSION Most cases of dermatomyositis, which the patient’s presentation and lab results suggested, require nerve conduction studies, a check of serum aldolase levels, and skin and musc.

The Use of Autoantibody Testing in a Postpartum Patient at Risk for Malignancy-Associated Dermatomyositis
https://www.medscape.com/viewarticle/950202

May 4th, 2021 - This article originally appeared on the Hospital for Special Surgery website. Case Report In May 2019, a 32-year-old woman developed a rash on her face, chest, and knuckles, initially thought to be contact dermatitis. She saw a second dermatologis...

Myositis mimics: Clues for making the right diagnosis
https://www.mdedge.com/rheumatology/article/195405/lupus-connective-tissue-diseases/myositis-mimics-clues-making-right
Sharon Worcester

Feb 28th, 2019 - A number of conditions can mimic myositis, but clues that can point to the correct diagnosis are often present in cases involving the mimics, according to Lisa Christopher-Stine, MD. Dr.

Anti-TIF1-Ab-Positive Dermatomyositis Linked to Higher Cancer Risk
https://www.medpagetoday.com/rheumatology/generalrheumatology/76902

Dec 13th, 2018 - Action Points Anti-TNF1-Ab positive dermatomyositis (DM) is linked to an elevated risk of cancer, especially ovarian cancer. This risk is present approximately 3 years on either side of DM onset. The link between DM and cancer is present for patie...

CPG Sec. 400.335 Fructose-Containing Drugs
http://www.fda.gov/regulatory-information/search-fda-guidance-documents/cpg-sec-400335-fructose-containing-drugs

Issued by: Guidance Issuing Office Office of Regulatory Affairs BACKGROUND: Hereditary fructose intolerance is a metabolic error due to the deficiency of fructose 1-phosphate aldolase in the liver. It is thought to be inherited as an autosomal rec...

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