ALLMedicine™ Antimitochondrial Antibody Center

Sep 15th, 2022 - Several autoantigens related to inflammatory myopathy have been identified. Antimitochondrial antibody M2 (AMA-M2) is known as one of the serologic hallmarks of primary biliary cholangitis (PBC). There have been several reports on the association ...

Aug 28th, 2022 - The ability to regulate B cell development has long been recognized to have therapeutic potential in a variety of autoimmune diseases. However, despite the presence of a classic autoantibody in primary biliary cholangitis (PBC), B cell depleting t...

Aug 2nd, 2022 - Primary biliary cholangitis (PBC) is an autoimmune chronic cholestatic liver disease characterized by progressive cholangiocyte and bile duct destruction leading to fibrosis and finally to liver cirrhosis. The presence of disease-specific serologi...

Jul 8th, 2022 - Practice Essentials Primary sclerosing cholangitis (PSC) is a chronic, progressive, inflammatory disease characterized by biliary inflammation and fibrosis leading to bile duct strictures and cirrhosis. PSC carries increased risk of hepatobiliary ...

Jul 8th, 2022 - Primary sclerosing cholangitis (PSC) is a chronic, progressive, inflammatory disease characterized by biliary inflammation and fibrosis leading to bile duct strictures and cirrhosis. PSC carries increased risk of hepatobiliary malignancies.[1] The...

Oct 6th, 2021 - Autoimmune liver diseases (AILD) are a group of immunologically induced hepatic damage that are either hepatocellular or cholestatic. The hepatocellular forms are characterized by a significant elevation of the serum alanine aminotransferase (ALT)...

Jul 12th, 2018 - To the Editor: A 38-year-old woman was diagnosed with common variable immune deficiency (CVID) by an immunologist at an outside institution 1 year prior to the current presentation. The diagnosis was based on history of severe recurrent sinopulmon.

Feb 1st, 2018 - THE CASE A 34-year-old woman was referred to the hepatology clinic for evaluation of an increased serum alkaline phosphatase (ALP) level. She was gravida 5 and in her 38th week of gestation.

Nov 15th, 2017 - The anti–tumor necrosis factor alpha agent infliximab is a beneficial option in the treatment of concurrent rheumatoid arthritis (RA) and primary biliary cholangitis (PBC), according to A. K.

Aug 24th, 2017 - Primary Biliary Cholangitis Guidelines on primary biliary cholangitis by the European Association for the Study of the Liver[13] Ultrasound is recommended as the first-line noninvasive imaging procedure to differentiate intrahepatic from extrahepa...

Jul 3rd, 2017 - THE CASE A 26-year-old healthy male veteran with bipolar disorder and post-traumatic stress disorder was referred for a gastroenterology consultation after a routine laboratory evaluation revealed elevated levels of aspartate aminotransferase (AST.