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About 2,728 results

ALLMedicine™ Acid Phosphatase Center

Research & Reviews  1,030 results

Bone Turnover Marker Profiling and Fracture Risk in Older Women: Fracture Risk from Age...
https://doi.org/10.1007/s00223-022-00996-8 10.1007/s11657-020-00871-9 10.1373/clinchem.2004.043901 10.1373/clinchem.2005.055541 10.1515/CCLM.2011.602 10.1007/s00223-014-9842-y 10.1359/JBMR.0301244 10.1359/jbmr.091006 10.1016/S2213-8587(17)30184-5 10.1007/s00198-010-1501-1 10.1007/s12020-016-0900-2 10.1016/S8756-3282(00)00325-2 10.1359/jbmr.2000.15.8.1526 10.1359/JBMR.041207 10.1210/jc.2006-2079 10.1136/ard.2007.077941 10.1359/jbmr.090526 10.1007/s00198-012-2106-7 10.1210/jc.2014-2646 10.1016/j.bone.2015.06.016 10.1007/s00198-014-2823-1 10.1302/0301-620X.89B12.18946 10.3109/17453674.2014.920987 10.1007/s00198-014-2951-7 10.1136/jech.48.5.489 10.1007/s00198-007-0543-5 10.1093/clinchem/46.3.332 10.1530/EC-15-0022 10.1515/cclm-2012-0531 10.1002/jbmr.2017 10.1016/j.jocd.2017.06.020 10.1210/jc.2015-3951 10.1002/jbmr.3471 10.1007/s00198-019-05043-1 10.1210/jc.2010-2878 10.1002/jbmr.3953 10.1007/s00198-012-2048-0 10.1002/jbmr.5650111021 10.1530/EJE-17-0585 10.1007/s11914-011-0059-y 10.1007/s11914-013-0158-z 10.1007/s00198-017-3976-5 10.1210/jc.2007-1508 10.1007/s00774-004-0537-8 10.1016/j.bone.2005.02.009
Calcified Tissue International; Ivaska KK, McGuigan FE et. al.

Jun 25th, 2022 - A major challenge in osteoporosis is to identify individuals at high fracture risk. We investigated six bone turnover markers (BTMs) to determine association with specific fracture types; the time-frame for risk prediction and whether these are in...

NLRC5 modulates bone metabolism and plays a role in periodontitis.
https://doi.org/10.1111/jre.13027
Journal of Periodontal Research; Wang W, Liu W et. al.

Jun 24th, 2022 - NOD-like receptor C5 (NLRC5) plays a significant role in the immune system, and is one of the largest members of the pattern recognition receptor family. Previous studies have found that NLRC5 might be involved in the regulation of various disease...

lncRNA SNHG15 as a ceRNA modulates Osteoclast Differentiation, Proliferation, and Metas...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9206997
Journal of Immunology Research; Wang Y, Zhu G et. al.

Jun 24th, 2022 - A growing number of studies have shown that long noncoding RNAs play an important role in osteoclast differentiation. However, there are few studies on the roles of lncRNA small nucleolar RNA host gene 15 (SNHG15) in osteoclast differentiation. Th...

A WNT protein therapeutic accelerates consolidation of a bone graft substitute in a pre...
https://doi.org/10.1111/jcpe.13674
Journal of Clinical Periodontology; Coyac BR, Wolf BJ et. al.

Jun 18th, 2022 - Autologous bone grafts consolidate faster than bone graft substitutes (BGSs) but resorb over time, which compromises implant support. We hypothesized that differences in consolidation rates affected the mechanical properties of grafts and implant ...

Adaptation of prelimbic cortex mediated by IL-6/STAT3/Acp5 pathway contributes to the c...
https://doi.org/10.1186/s12974-022-02503-0 10.2741/3598 10.1016/j.jad.2010.10.022 10.4088/JCP.08m04114 10.1016/j.expneurol.2016.08.010 10.3389/fncir.2019.00074 10.1016/0006-8993(89)91144-X 10.1016/j.jpain.2017.03.008 10.1126/science.1190287 10.1016/j.neuroscience.2017.08.049 10.1038/nrn1033 10.1038/s41593-019-0429-9 10.1038/nrn1519 10.1124/pr.113.008144 10.1176/appi.ajp.2015.15020152 10.1097/ALN.0000000000002130 10.1016/S0304-3959(00)00331-6 10.1053/eujp.2000.0177 10.1017/S0033291700032712 10.1111/j.1365-2036.2007.03316.x 10.1016/j.jpsychires.2006.05.013 10.1002/hup.717 10.1002/mrm.1910340409 10.1016/S0304-3959(00)00276-1 10.1016/j.jneumeth.2018.06.026 10.1097/j.pain.0000000000000805 10.1038/nprot.2007.44 10.1016/j.neuropharm.2017.10.038 10.1016/j.nicl.2017.07.014 10.1016/j.jneumeth.2008.04.012 10.1038/s41467-019-12049-0 10.31887/DCNS.2017.19.1/fdacquisto 10.3389/fnins.2019.00384 10.1177/0091270010394852 10.1016/j.autrev.2020.102504 10.1038/srep09009 10.1016/j.biopsych.2020.11.018 10.1016/j.biopsych.2019.10.021 10.1016/j.braindev.2006.10.001 10.1503/jpn.160225 10.1074/jbc.RA119.007533 10.1038/ncomms8660 10.2220/biomedres.38.123 10.1177/002215540104900312 10.1177/002215540004800207 10.1038/mp.2009.91 10.1186/1742-2094-7-43 10.1073/pnas.1408023111
Journal of Neuroinflammation; Zhao YT, Deng J et. al.

Jun 12th, 2022 - The adaption of brain region is fundamental to the development and maintenance of nervous system disorders. The prelimbic cortex (PrL) participates in the affective components of the pain sensation. However, whether and how the adaptation of PrL c...

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Drugs  3 results see all →

Clinicaltrials.gov  22 results

pTVG-HP and Nivolumab in Patients With Non-Metastatic PSA-Recurrent Prostate Cancer
https://clinicaltrials.gov/ct2/show/NCT03600350

Feb 8th, 2022 - The purpose of this study is to evaluate the safety of an investigational DNA vaccine, pTVG-HP, a plasmid DNA encoding human prostatic acid phosphatase (PAP), in combination with nivolumab, and the efficacy of this combination in decreasing serum ...

Assessment of TRACP-5b in Primary and Secondary Osteoporosis
https://clinicaltrials.gov/ct2/show/NCT05103592

Nov 15th, 2021 - Osteoporosis is a disease characterized by low bone density and a deterioration of bone microarchitecture that reduces bone strength and increases the risk of fracture. The hallmark of osteoporosis is the loss of both bone mineral and bone matrix....

Vaccine Therapy and Pembrolizumab in Treating Patients With Hormone-Resistant, Metastatic Prostate Cancer
https://clinicaltrials.gov/ct2/show/NCT02499835

Sep 29th, 2021 - PRIMARY OBJECTIVES: I. To evaluate the safety of pembrolizumab in combination with pTVG-HP (pTVG-HP plasmid DNA vaccine) in patients with castration-resistant, metastatic prostate cancer. II. To determine the 6-month progression-free survival and ...

Radiation Therapy in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer Receiving Sipuleucel-T
https://clinicaltrials.gov/ct2/show/NCT01833208

Aug 5th, 2021 - PRIMARY OBJECTIVES: I. To assess whether radiation therapy (RT) increases the immunogenic potential or sipuleucel-T in participants with castration recurrent prostate cancer. II. To assess systemic changes to the immune system and genetic changes ...

Two-Arm Study of a DNA Vaccine Encoding Prostatic Acid Phosphatase (PAP) in Patients With Non-Metastatic Castrate-Resistant Prostate Cancer
https://clinicaltrials.gov/ct2/show/NCT00849121

Nov 21st, 2019 - The investigators are trying to find new methods to treat prostate cancer. The approach is to try to enhance patients' own immune response against the cancer. In this study, the investigators will be testing the safety of a vaccine that may be abl...

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News  36 results

Immune Correlates May Indicate Responsiveness to Ipilimumab in mCRPC
https://www.onclive.com/view/immune-correlates-may-indicate-responsiveness-to-ipilimumab-in-mcrpc

Oct 6th, 2021 - Sumit Subudhi, MD, PhD A subset of patients with metastatic castration-resistant prostate cancer (mCRPC) who have low tumor mutational burden (TMB) may benefit from checkpoint inhibition with ipilimumab (Yervoy) if the tumor has a high density of...

Vogelzang Disputes 'Weak' Guideline Rating for Sipuleucel-T
https://www.onclive.com/view/vogelzang-disputes-weak-guideline-rating-for-sipuleucel-t

Oct 6th, 2021 - Nicholas J. Vogelzang, MD In a recent guideline for the treatment of men with metastatic castration-resistant prostate cancer (mCRPC), the American Society of Clinical Oncology (ASCO) and Cancer Care Ontario (CCO) shared their thoughts on the imp...

Sipuleucel-T Helps ADT Boost Prostate Cancer Immunity
https://www.onclive.com/view/sipuleucel-t-helps-adt-boost-prostate-cancer-immunity

Oct 6th, 2021 - Emmanuel S. Antonarakis, MBBCh Sipuleucel-T (Provenge) is effective when given either before or after androgen deprivation therapy (ADT) in men with biochemically recurrent prostate cancer (BRPC) who face a high risk of developing metastases, a s...

Robust Sipuleucel-T Immune Activity Is Detailed in Pooled Data Analysis
https://www.onclive.com/view/robust-sipuleucel-t-immune-activity-is-detailed-in-pooled-data-analysis

Oct 6th, 2021 - Daniel P. Petrylak, MD Professor, Medical Oncology Director, Prostate Cancer Research Group Yale Cancer Center Leader, Genitourinary Cancers Medical Oncology Team Smilow Cancer Hospital at Yale-New Haven New Haven, CT Patients who rece...

Diagnostic and Therapeutic Applications of PSMA in Prostate Cancer
https://www.onclive.com/view/diagnostic-and-therapeutic-applications-of-psma-in-prostate-cancer

Jul 30th, 2021 - Neal Shore, MD: Interestingly, to think about PSMA [prostate-specific membrane antigen] now as an antigenic expression, we have to go back and look historically at how we were wedded to acid phosphatase as the key expressive assay back in the 1970...

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