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About 932 results

ALLMedicine™ Methylmalonic Acid Center

Research & Reviews  455 results

EXPRESS: Personalising laboratory medicine in the âreal worldâ: assessing clinical util...
https://doi.org/10.1177/00045632211003605
Annals of Clinical Biochemistry; Murphy MJ, Brandie F et. al.

Mar 15th, 2021 - Assessing the pre and post test probability of disease in the context of routine health care is challenging. We wished to study how test performance parameters relating to clinical utility vary by clinical indication in a âreal worldâ setting. The...

Maternal Vitamin B12 Status and Risk of Cleft Lip and Cleft Palate Birth Defects in Tam...
https://doi.org/10.1177/1055665621998394
The Cleft Palate-craniofacial Journal : Official Publicat... Munger RG, Kuppuswamy R et. al.

Mar 9th, 2021 - The causal role of maternal nutrition in orofacial clefts is uncertain. We tested hypotheses that low maternal vitamin B12 and low folate status are each associated with an increased risk of isolated cleft lip with or without cleft palate (CL±P) i...

Methylmalonic acid, vitamin B12, renal function, and risk of all-cause mortality in the...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7726887
BMC Medicine; Riphagen IJ, Minović I et. al.

Dec 10th, 2020 - Methylmalonic acid (MMA) is best known for its use as a functional marker of vitamin B12 deficiency. However, MMA concentrations not only depend on adequate vitamin B12 status, but also relate to renal function and endogenous production of propion...

Test utilization for the diagnosis of vitamin B12 and folate deficiency in local clinic...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7676195
Journal of Clinical Laboratory Analysis; Choi R, Oh Y et. al.

Nov 6th, 2020 - Current guidelines pertaining to diagnosing macrocytic anemia in association with vitamin B12 and folate deficiency recommend that vitamin B12, folate, homocysteine, and methylmalonic acid assays should be assessed concurrently due to their close ...

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Guidelines  1 results

Guidelines for the diagnosis and treatment of cobalamin and folate disorders.
https://doi.org/10.1111/bjh.12959
British Journal of Haematology; Devalia V, Hamilton MS et. al.

Jun 19th, 2014 - The clinical picture is the most important factor in assessing the significance of test results assessing cobalamin status because there is no 'gold standard' test to define deficiency. Serum cobalamin currently remains the first-line test, with a...

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Clinicaltrials.gov  465 results

EXPRESS: Personalising laboratory medicine in the âreal worldâ: assessing clinical util...
https://doi.org/10.1177/00045632211003605
Annals of Clinical Biochemistry; Murphy MJ, Brandie F et. al.

Mar 15th, 2021 - Assessing the pre and post test probability of disease in the context of routine health care is challenging. We wished to study how test performance parameters relating to clinical utility vary by clinical indication in a âreal worldâ setting. The...

Maternal Vitamin B12 Status and Risk of Cleft Lip and Cleft Palate Birth Defects in Tam...
https://doi.org/10.1177/1055665621998394
The Cleft Palate-craniofacial Journal : Official Publicat... Munger RG, Kuppuswamy R et. al.

Mar 9th, 2021 - The causal role of maternal nutrition in orofacial clefts is uncertain. We tested hypotheses that low maternal vitamin B12 and low folate status are each associated with an increased risk of isolated cleft lip with or without cleft palate (CL±P) i...

Methylmalonic acid, vitamin B12, renal function, and risk of all-cause mortality in the...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7726887
BMC Medicine; Riphagen IJ, Minović I et. al.

Dec 10th, 2020 - Methylmalonic acid (MMA) is best known for its use as a functional marker of vitamin B12 deficiency. However, MMA concentrations not only depend on adequate vitamin B12 status, but also relate to renal function and endogenous production of propion...

Test utilization for the diagnosis of vitamin B12 and folate deficiency in local clinic...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7676195
Journal of Clinical Laboratory Analysis; Choi R, Oh Y et. al.

Nov 6th, 2020 - Current guidelines pertaining to diagnosing macrocytic anemia in association with vitamin B12 and folate deficiency recommend that vitamin B12, folate, homocysteine, and methylmalonic acid assays should be assessed concurrently due to their close ...

see more →

News  11 results

Treating Vitamin B12 Deficiency: What Formulation Is Best?
https://www.medscape.com/viewarticle/926301_1

Mar 8th, 2020 - An 82-year-old woman complaining of fatigue has a hemoglobin level of 8 g/dL with a mean corpuscular volume of 114 fL. Her B12 level is 90 pg/mL (normal level: > 200). Folic acid level is normal. Methylmalonic acid level is high.

Treating Vitamin B12 Deficiency: What Formulation Is Best?
https://www.medscape.com/viewarticle/926301

Mar 8th, 2020 - An 82-year-old woman complaining of fatigue has a hemoglobin level of 8 g/dL with a mean corpuscular volume of 114 fL. Her B12 level is 90 pg/mL (normal level: > 200). Folic acid level is normal. Methylmalonic acid level is high. You must Log In t...

Vitamin B12 deficiency
https://www.mdedge.com/ccjm/article/100685/gastroenterology/vitamin-b12-deficiency?channel=234
Kenneth R. Phillips, MS, MD, FCCP

Jan 1st, 2016 - To the Editor: In the article “ An unusual cause of vitamin B 12 and iron deficiency ,”1 the diagnosis of vitamin B 12 deficiency was made only by a vitamin B 12 level of 108 pg/mL. According to Harrison’s Principles of Internal Medicine, 18th edi.

EASD: Metformin-induced B12 deficiency linked to diabetic neuropathy
https://www.mdedge.com/neurology/article/103171/diabetes/easd-metformin-induced-b12-deficiency-linked-diabetic-neuropathy
Sara Freeman

Sep 30th, 2015 - STOCKHOLM – Clinicians might want to consider more routinely monitoring levels of vitamin B12 in their diabetic patients who are using metformin, according to new data from the HOME (Hyperinsulinaemia: the Outcome of Its Metabolic Effects) randomi.

Metformin-induced B12 Deficiency Linked to Diabetic Neuropathy
https://www.mdedge.com/clinicianreviews/article/103255/diabetes/metformin-induced-b12-deficiency-linked-diabetic-neuropathy
Sara Freeman

Sep 30th, 2015 - STOCKHOLM – Clinicians might want to consider more routinely monitoring levels of vitamin B12 in their diabetic patients who are using metformin, according to new data from the HOME (Hyperinsulinaemia: the Outcome of Its Metabolic Effects) randomi.

see more →