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About 1,997 results

ALLMedicine™ Vitamin C Center

Research & Reviews  809 results

Transport of vitamin C in cancer.
https://doi.org/10.1089/ars.2020.8166
Antioxidants & Redox Signaling; Muñoz-Montesino C, Peña E et. al.

Feb 20th, 2021 - Vitamin C is a powerful antioxidant that has an intricate relationship with cancer, studied for more than 60 years. However, the specific mechanisms that allow malignant cells to uptake, metabolize and compartmentalize vitamin C remains unclear. I...

Combination and efficiency: preparation of dissolving microneedles array loaded with tw...
https://doi.org/10.1016/j.ejps.2021.105749
European Journal of Pharmaceutical Sciences : Official Jo... Wang YS, Yang WH et. al.

Feb 13th, 2021 - Hyperpigmentation is a common skin disorder caused by excessive melanogenesis and uneven dispersion of melanin in the skin. To combine multiple active agents with an efficient transdermal drug delivery system is an effective strategy to combat UV ...

Safety and effectiveness of high-dose vitamin C in patients with COVID-19: a randomized...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877333
European Journal of Medical Research; JamaliMoghadamSiahkali S, Zarezade B et. al.

Feb 12th, 2021 - Vitamin C is an essential water-soluble nutrient that functions as a key antioxidant and has been proven to be effective for boosting immunity. In this study, we aimed to assess the efficacy of adding high-dose intravenous vitamin C (HDIVC) to the...

A Stabilizing Agent, PCA/DTPA, Improves Plasma Storage Life for the Chromsystems Vitami...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884199
Annals of Laboratory Medicine; Collie JT, Hudson EP et. al.

Feb 4th, 2021 - The commonly used Chromsystems vitamin C (ascorbate) assay (Munich, Germany) has a sample storage life of five days at -20°C. Stabilizing agents have been successfully used to increase longevity; however, their suitability with this commercial ass...

Molecular mechanism for vitamin C-derived C5-glyceryl-methylcytosine DNA modification c...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7854593
Nature Communications; Li W, Zhang T et. al.

Feb 3rd, 2021 - C5-glyceryl-methylcytosine (5gmC) is a novel DNA modification catalyzed by algal TET homologue CMD1 using vitamin C (VC) as co-substrate. Here, we report the structures of CMD1 in apo form and in complexes with VC or/and dsDNA. CMD1 exhibits compa...

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Guidelines  3 results

High-dose vitamin C enhances cancer immunotherapy
https://stm.sciencemag.org/content/12/532/eaay8707
Science Translational Medicine; Magri A,et al

Feb 19th, 2020 - Vitamin C (VitC) is known to directly impair cancer cell growth in preclinical models, but there is little clinical evidence on its antitumoral efficacy. In addition, whether and how VitC modulates anticancer immune responses is mostly unknown. He...

Vitamin C - Fact Sheet for Health Professionals
https://ods.od.nih.gov/factsheets/VitaminC-HealthProfessional/
National Institutes of Health (NIH)

Vitamin C, also known as L-ascorbic acid, is a water-soluble vitamin that is naturally present in some foods, added to others, and available as a dietary supplement. Humans, unlike most animals, are unable to synthesize vitamin C endogenously, so ...

High-Dose Vitamin C (PDQ®)–Health Professional Version
https://www.cancer.gov/about-cancer/treatment/cam/hp/vitamin-c-pdq?cid=eb_govdel
National Cancer Institute

This cancer information summary provides an overview of the use of high-dose vitamin C (also known as ascorbate or L-ascorbic acid) as a treatment for people with cancer. This summary includes a brief history of early clinical trials of high-dose ...

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Drugs  165 results see all →

Clinicaltrials.gov  997 results

More Disappointing Results for Vitamin C, Thiamine and Hydrocortisone in Sepsis
https://www.medscape.com/viewarticle/946309

Feb 24th, 2021 - NEW YORK (Reuters Health) - Among critically ill patients with sepsis, treatment with hydrocortisone, vitamin C (ascorbic acid) and thiamine (HAT) did not improve outcome in the randomized controlled VICTAS trial. "Our study suggested that the lar...

Transport of vitamin C in cancer.
https://doi.org/10.1089/ars.2020.8166
Antioxidants & Redox Signaling; Muñoz-Montesino C, Peña E et. al.

Feb 20th, 2021 - Vitamin C is a powerful antioxidant that has an intricate relationship with cancer, studied for more than 60 years. However, the specific mechanisms that allow malignant cells to uptake, metabolize and compartmentalize vitamin C remains unclear. I...

Combination and efficiency: preparation of dissolving microneedles array loaded with tw...
https://doi.org/10.1016/j.ejps.2021.105749
European Journal of Pharmaceutical Sciences : Official Jo... Wang YS, Yang WH et. al.

Feb 13th, 2021 - Hyperpigmentation is a common skin disorder caused by excessive melanogenesis and uneven dispersion of melanin in the skin. To combine multiple active agents with an efficient transdermal drug delivery system is an effective strategy to combat UV ...

Safety and effectiveness of high-dose vitamin C in patients with COVID-19: a randomized...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877333
European Journal of Medical Research; JamaliMoghadamSiahkali S, Zarezade B et. al.

Feb 12th, 2021 - Vitamin C is an essential water-soluble nutrient that functions as a key antioxidant and has been proven to be effective for boosting immunity. In this study, we aimed to assess the efficacy of adding high-dose intravenous vitamin C (HDIVC) to the...

A Stabilizing Agent, PCA/DTPA, Improves Plasma Storage Life for the Chromsystems Vitami...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884199
Annals of Laboratory Medicine; Collie JT, Hudson EP et. al.

Feb 4th, 2021 - The commonly used Chromsystems vitamin C (ascorbate) assay (Munich, Germany) has a sample storage life of five days at -20°C. Stabilizing agents have been successfully used to increase longevity; however, their suitability with this commercial ass...

see more →

News  23 results

More Disappointing Results for Vitamin C, Thiamine and Hydrocortisone in Sepsis
https://www.medscape.com/viewarticle/946309

Feb 24th, 2021 - NEW YORK (Reuters Health) - Among critically ill patients with sepsis, treatment with hydrocortisone, vitamin C (ascorbic acid) and thiamine (HAT) did not improve outcome in the randomized controlled VICTAS trial. "Our study suggested that the lar...

High-dose vitamin C enhances cancer immunotherapy
https://stm.sciencemag.org/content/12/532/eaay8707
Science Translational Medicine; Magri A,et al

Feb 19th, 2020 - Vitamin C (VitC) is known to directly impair cancer cell growth in preclinical models, but there is little clinical evidence on its antitumoral efficacy. In addition, whether and how VitC modulates anticancer immune responses is mostly unknown. He...

Vitamin C regulates HSCs, curbs AML development
https://www.mdedge.com/hematology-oncology/article/185475/leukemia-myelodysplasia-transplantation/vitamin-c-regulates-hscs-curbs-aml
HT Staff

Aug 24th, 2017 - Image by Lance Liotta AML cells Researchers have described a molecular mechanism that could help explain the link between low vitamin C (ascorbate) levels and acute myeloid leukemia (AML). The team found that mice with low levels of ascorbate in t.

Gout: No Help From Vitamin C
https://www.staging.medscape.com/viewarticle/804343

May 15th, 2013 - Vitamin C added little to the urate-lowering effect of standard gout treatment and was clinically ineffective when used alone, according to a small randomized trial published online May 16 in Arthritis & Rheumatism. According to lead author Lisa S...

Gout: No Help From Vitamin C
https://www.medscape.com/viewarticle/804343

May 15th, 2013 - Vitamin C added little to the urate-lowering effect of standard gout treatment and was clinically ineffective when used alone, according to a small randomized trial published online May 16 in Arthritis & Rheumatism. According to lead author Lisa S...

see more →