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About 12,918 results

ALLMedicine™ Vitamin K Center

Research & Reviews  4,122 results

The international normalized ratio - Great for prediction of bleeding in patients takin...
https://doi.org/10.1111/jth.15756
Journal of Thrombosis and Haemostasis : JTH; Giannini EG, Lisman T

Jun 27th, 2022 - The international normalized ratio - Great for prediction of bleeding in patients taking vitamin K antagonists, useless for prediction of bleeding in patients with chronic liver disease.|2022|Giannini EG,Lisman T,|

Time-Trends of Drug-Drug Interactions among Elderly Outpatients in the Piedmont Region ...
https://doi.org/10.3390/ijerph19127353
International Journal of Environmental Research and Publi... Galai E, Scotti L et. al.

Jun 25th, 2022 - Adverse drug reactions (ADRs) are a major health problem in the primary care setting, particularly among the elderly population. While the high frequency of ADRs in the elderly has several causes, a major and common determinant is polypharmacy, wh...

Warfarin resistance: possibilities to solve this problem. A case report.
https://doi.org/10.1177/03000605221103959
The Journal of International Medical Research; Mostbauer H, Nishkumay O et. al.

Jun 25th, 2022 - Effective prevention of thromboembolism is essential for patients with mechanical prosthetic heart valves. For this group of patients, vitamin K antagonists (VKAs) remain the drug group of choice despite the widespread use of new anticoagulants in...

Structural and cellular basis of vitamin K antagonism.
https://doi.org/10.1111/jth.15800
Journal of Thrombosis and Haemostasis : JTH; Liu S, Shen G et. al.

Jun 25th, 2022 - Vitamin K antagonists (VKAs), such as warfarin, are oral anticoagulants widely used to treat and prevent thromboembolic diseases. Therapeutic use of these drugs requires frequent monitoring and dose adjustments, whereas overdose often cause severe...

Plasmatic Factor V as a Predictor of Graft Dysfunction After Liver Transplantation
https://clinicaltrials.gov/ct2/show/NCT03396016

Jun 24th, 2022 - There is no widely accepted biomarker to assess hepatic function after Liver Transplantation (LT). Factor V is a coagulation cofactor that is primarily produced by the liver. Factor V has a short half-life and its production does not depend on vit...

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Guidelines  16 results

American College of Gastroenterology-Canadian Association of Gastroenterology Clinical ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8966740
The American Journal of Gastroenterology; Abraham NS, Barkun AN et. al.

Mar 18th, 2022 - We conducted systematic reviews of predefined clinical questions and used the Grading of Recommendations, Assessment, Development and Evaluations approach to develop recommendations for the periendoscopic management of anticoagulant and antiplatel...

Regional anaesthesia in patients on antithrombotic drugs: Joint ESAIC/ESRA guidelines.
https://doi.org/10.1097/EJA.0000000000001600
European Journal of Anaesthesiology; Kietaibl S, Ferrandis R et. al.

Jan 5th, 2022 - Bleeding is a potential complication after neuraxial and peripheral nerve blocks. The risk is increased in patients on antiplatelet and anticoagulant drugs. This joint guideline from the European Society of Anaesthesiology and Intensive Care and t...

American Society of Hematology 2020 guidelines for management of venous thromboembolism...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556153
Blood Advances; Ortel TL, Neumann I et. al.

Oct 3rd, 2020 - Venous thromboembolism (VTE), which includes deep vein thrombosis (DVT) and pulmonary embolism (PE), occurs in ∼1 to 2 individuals per 1000 each year, corresponding to ∼300 000 to 600 000 events in the United States annually. These evidence-based ...

2018 Focused Update of the Canadian Cardiovascular Society Guidelines for the Managemen...
https://doi.org/10.1016/j.cjca.2018.08.026
The Canadian Journal of Cardiology; Andrade JG, Verma A et. al.

Nov 9th, 2018 - The Canadian Cardiovascular Society (CCS) Atrial Fibrillation Guidelines Committee provides periodic reviews of new data to produce focused updates that address clinically important advances in atrial fibrillation (AF) management. This 2018 Focuse...

THE USE OF VITAMINS AND MINERALS IN SKELETAL HEALTH: AMERICAN ASSOCIATION OF CLINICAL E...
https://doi.org/10.4158/PS-2018-0050
Endocrine Practice : Official Journal of the American Col... Hurley DL, Binkley N et. al.

Jul 24th, 2018 - 25(OH)D = 25-hydroxyvitamin D; BMD = bone mineral density; CV = cardiovascular; GI = gastrointestinal; IOM = Institute of Medicine; PTH = parathyroid hormone; RCT = randomized controlled trial; αTF = α-tocopherol; ucOC = undercarboxylated osteocal...

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Drugs  77 results see all →

Clinicaltrials.gov  409 results

Plasmatic Factor V as a Predictor of Graft Dysfunction After Liver Transplantation
https://clinicaltrials.gov/ct2/show/NCT03396016

Jun 24th, 2022 - There is no widely accepted biomarker to assess hepatic function after Liver Transplantation (LT). Factor V is a coagulation cofactor that is primarily produced by the liver. Factor V has a short half-life and its production does not depend on vit...

CHAMPION-AF Clinical Trial
https://clinicaltrials.gov/ct2/show/NCT04394546

Jun 22nd, 2022 - This study is a prospective, randomized, multi-center global investigation. Subjects will be randomized to either the WATCHMAN FLX Left Atrial Appendage Closure Device ("Device Group") or a commercially available non-vitamin K oral anticoagulant (...

The InterVitaminK Trial - Effects of Vitamin K Supplementation on Cardiovascular, Metabolic, and Bone Health
https://clinicaltrials.gov/ct2/show/NCT05259046

Jun 22nd, 2022 - Background: Research suggest that vitamin K may have protective effects against non-communicable and age-related diseases as diverse as cardiovascular disease (CVD), osteoporosis, and type 2 diabetes (T2D). However, there is a need for larger stud...

A Study to Gather Information About Rivaroxaban in Patients in Sweden With Cancer Who Also Have Thrombosis (OSCAR-SE)
https://clinicaltrials.gov/ct2/show/NCT05150938

Jun 21st, 2022 - This is an observational study in which patient data from the past on venous thromboembolism (VTE) in patients with cancer is studied. VTE is a condition in which a patient has problems due to the formation of blood clots in the veins. Blood clots...

Study to Gather Information About the Safety of Oral Anticoagulation Drugs and How Well These Drugs Work in Real World for Patients With Non-valvular Atrial Fibrillation (Irregularly Heart Beats Wh...
https://clinicaltrials.gov/ct2/show/NCT04249401

Jun 21st, 2022 - Oral anticoagulant (OAC) treatment with either vitamin K antagonists (VKAs) or non-vitamin K antagonist oral anticoagulants (NOACs) is essential in patients with atrial fibrillation for the prevention of stroke or systemic embolism (SE) a conditio...

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News  540 results

Recurrent Stroke Risk High in AF, Even With Anticoagulants
https://www.medscape.com/viewarticle/973963

May 13th, 2022 - Patients with atrial fibrillation (AF) who suffer an ischemic stroke while taking direct oral anticoagulants (DOACs) or vitamin K antagonists (VKA) have a dangerously high risk of recurrent stroke and death, a new study shows. Researchers found a ...

Retiform Purpura on the Legs
https://www.mdedge.com/dermatology/article/254484/dermatopathology/retiform-purpura-legs
Mark C. Marchitto, MD, Liesl Grenier, MD et. al.

May 10th, 2022 - The Diagnosis: Calciphylaxis Histopathology revealed epidermal and dermal necrosis, a perivascular neutrophilic infiltrate, and scattered microcalcifications within small- and medium-sized subcutaneous vessels, consistent with a diagnosis of calci.

Extended Therapy for VTE: Does Anticoagulant Choice Matter?
https://www.medpagetoday.com/cardiology/prevention/97663

Mar 15th, 2022 - For those considering extended anticoagulation after initial therapy for venous thromboembolism (VTE), prescription claims databases showed that apixaban (Eliquis) could be a better choice than warfarin. People prescribed the direct oral anticoagu...

Fast Five Quiz: Anticoagulation in Older Patients With Atrial Fibrillation
https://www.medscape.com/viewarticle/966147

Mar 9th, 2022 - Older patients with atrial fibrillation (AF) are included in the group of patients at high risk for stroke. A multidisciplinary approach to managing AF in older patients can mitigate risk for stroke. Oral anticoagulation is the cornerstone of mana...

Are Thrombolytics for Stroke Safe for Patients on NOACs?
https://www.medscape.com/viewarticle/969163

Feb 25th, 2022 - Recent use of non-vitamin K antagonist oral anticoagulants (NOACs) is not associated with increased risk for bleeding following treatment with intravenous alteplase for ischemic stroke, new data suggest. In a prespecified, retrospective analysis o...

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Patient Education  3 results see all →