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About 2,274 results

ALLMedicine™ Metabolic Alkalosis Center

Research & Reviews  617 results

Diagnosis and outpatient management of Gitelman syndrome from the first trimester of pr...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8118020
BMJ Case Reports; Lim M, Gannon D

May 13th, 2021 - A 32-year-old woman presented with an incidental finding of hypokalaemia on routine bloods at 9 weeks of a second pregnancy, on a background of lifelong salt craving. Her previous pregnancy was uncomplicated. She had no previous significant medica...

A rare case of ectopic ACTH syndrome with rhabdomyolysis.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8111963
BMC Endocrine Disorders; Qiang W, Song S et. al.

May 11th, 2021 - Manifestations of hypokalaemia in ectopic adrenocorticotropic hormonesyndrome(EAS) vary from mild muscle weakness to life-threatening arrhythmia. Herein, we present a rare case of EAS with concomitant rhabdomyolysis(RM) as a result of intractable ...

The molecular mechanism of CFTR- and secretin-dependent renal bicarbonate excretion.
https://doi.org/10.1113/JP281285
The Journal of Physiology; Berg P, Svendsen SL et. al.

May 8th, 2021 - This review summarizes the newly discovered molecular mechanism of secretin-stimulated urine HCO3 - excretion and the role of cystic fibrosis transmembrane conductance regulator (CFTR) in renal HCO3 - excretion. The secretin receptor is functional...

Hypokalaemic paralysis and metabolic alkalosis in a patient with Sjögren syndrome: a ca...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8086307
BMC Nephrology; Ranaweerage R, Perera S et. al.

May 1st, 2021 - Acquired Gitelman syndrome is a very rare disorder reported in association with autoimmune disorders, mostly Sjögren syndrome. It is characterized by the presence of hypokalaemic metabolic alkalosis, hypocalciuria, hypomagnesaemia and hyper-renina...

Type 3 antenatal Bartter syndrome presenting with mild polyuria.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8030685
BMJ Case Reports; Otsubo Y, Kano Y et. al.

Apr 8th, 2021 - Bartter syndrome (BS) is a well-recognised inherited tubular dysfunction that causes polyuria, metabolic alkalosis and hypokalaemia. Among BS cases, antenatal/neonatal BS (ABS) usually shows distinct polyhydramnios prenatally and presents features...

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Guidelines  2 results

Diagnosis and management of Bartter syndrome: executive summary of the consensus and re...
https://doi.org/10.1016/j.kint.2020.10.035
Kidney International; Konrad M, Nijenhuis T et. al.

Jan 29th, 2021 - Bartter syndrome is a rare inherited salt-losing renal tubular disorder characterized by secondary hyperaldosteronism with hypokalemic and hypochloremic metabolic alkalosis and low to normal blood pressure. The primary pathogenic mechanism is defe...

Dietary Chloride Deficiency Syndrome: Pathophysiology, History, and Systematic Literature Review
https://pubmed.ncbi.nlm.nih.gov/33182508/
Nutrients Signorelli GC, Bianchetti MG et. al.

Metabolic alkalosis may develop as a consequence of urinary chloride (and sodium) wasting, excessive loss of salt in the sweat, or intestinal chloride wasting, among other causes. There is also a likely underrecognized association between poor sal...

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Drugs  505 results see all →

Clinicaltrials.gov  1,139 results

Potassium chloride - potassium chloride tablet, extended release-American Health Packaging
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c1024e6d-1a91-4609-b1a8-e5ef898c15a4

May 16th, 2021 - BECAUSE OF REPORTS OF INTESTINAL AND GASTRIC ULCERATION AND BLEEDING WITH CONTROLLED-RELEASE POTASSIUM CHLORIDE PREPARATIONS, THESE DRUGS SHOULD BE RESERVED FOR THOSE PATIENTS WHO CANNOT TOLERATE OR REFUSE TO TAKE LIQUID OR EFFERVESCENT POTASSIUM ...

Diagnosis and outpatient management of Gitelman syndrome from the first trimester of pr...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8118020
BMJ Case Reports; Lim M, Gannon D

May 13th, 2021 - A 32-year-old woman presented with an incidental finding of hypokalaemia on routine bloods at 9 weeks of a second pregnancy, on a background of lifelong salt craving. Her previous pregnancy was uncomplicated. She had no previous significant medica...

A rare case of ectopic ACTH syndrome with rhabdomyolysis.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8111963
BMC Endocrine Disorders; Qiang W, Song S et. al.

May 11th, 2021 - Manifestations of hypokalaemia in ectopic adrenocorticotropic hormonesyndrome(EAS) vary from mild muscle weakness to life-threatening arrhythmia. Herein, we present a rare case of EAS with concomitant rhabdomyolysis(RM) as a result of intractable ...

Potassium chloride - potassium chloride capsule, extended release-Granules Pharmaceuticals Inc
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c1f4832d-4d5c-8c49-e053-2a95a90ac9fe

May 9th, 2021 - Potassium chloride extended-release capsules are indicated for the treatment and prophylaxis of hypokalemia in adults and children with or without metabolic alkalosis, in patients for whom dietary management with potassium-rich foods or diuretic d...

The molecular mechanism of CFTR- and secretin-dependent renal bicarbonate excretion.
https://doi.org/10.1113/JP281285
The Journal of Physiology; Berg P, Svendsen SL et. al.

May 8th, 2021 - This review summarizes the newly discovered molecular mechanism of secretin-stimulated urine HCO3 - excretion and the role of cystic fibrosis transmembrane conductance regulator (CFTR) in renal HCO3 - excretion. The secretin receptor is functional...

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News  11 results

A 5-Week-Old Boy With Progressive Nonbilious Vomiting: Osmosis USMLE Study Question
https://www.medscape.com/viewarticle/879904_2

Jun 22nd, 2017 - Answer: C. Hypochloremic hypokalemic metabolic alkalosis Infantile hypertrophic pyloric stenosis classically presents with progressive nonbilious projectile emesis and an enlarged pylorus (described as an "olive") upon abdominal examination. Prolo...

Acetazolamide doesn’t reduce duration of mechanical ventilation
https://www.mdedge.com/pulmonary-health-hub/article/106242/pulmonology/acetazolamide-doesnt-reduce-duration-mechanical
Mary Ann Moon

Feb 2nd, 2016 - Acetazolamide failed to reduce the duration of invasive mechanical ventilation in chronic obstructive pulmonary disease (COPD) patients who had pure or mixed metabolic alkalosis, according to results from a clinical trial published online Feb. 2 i.

Acetazolamide Fails to Reduce COPD Ventilation Time
https://www.medpagetoday.com/pulmonology/smokingcopd/55963

Feb 2nd, 2016 - Action Points Treatment with acetazolamide (Diamox) did not significantly reduce invasive mechanical ventilation times among hospitalized patients with chronic obstructive pulmonary disease and metabolic alkalosis, but the drug may still benefit t...

COPD Drug Does Not Significantly Reduce Ventilator Time
https://www.staging.medscape.com/viewarticle/858184

Feb 1st, 2016 - Acetazolamide, a drug that has been commonly used for chronic obstructive pulmonary disease (COPD), does not significantly reduce time on a ventilator for patients with the disease and metabolic alkalosis, new data show. However, the difference be...

COPD Drug Does Not Significantly Reduce Ventilator Time
https://www.medscape.com/viewarticle/858184

Feb 1st, 2016 - Acetazolamide, a drug that has been commonly used for chronic obstructive pulmonary disease (COPD), does not significantly reduce time on a ventilator for patients with the disease and metabolic alkalosis, new data show. However, the difference be...

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