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About 1,028 results

ALLMedicine™ Hypernatremia Center

Research & Reviews  359 results

Topiramate-induced severe electrolyte abnormalities and hypernatremia leading to centra...
https://doi.org/10.1136/bcr-2021-245870
BMJ Case Reports; Muaddi L, Osman O et. al.

Dec 2nd, 2021 - Central pontine myelinolysis (CPM) develops due to acute hypernatremia from a normal baseline serum sodium in the setting of electrolyte abnormalities induced by topiramate use. Topiramate is a commonly used medication with several indications inc...

Importance of Early Genetic Sequencing in Neonates Admitted to NICU with Recurrent Hype...
https://doi.org/10.1159/000519634
Neonatology Hu L, Yang L et. al.

Nov 22nd, 2021 - The genetic characteristics in neonates admitted to the NICU with recurrent hypernatremia remained unknown. We aimed to implement early genetic sequencing to identify possible genetic etiologies, optimize the treatment, and improve the outcome. We...

Effectiveness of a novel 1% glucose isotonic electrolyte solution for intraoperative fl...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8593312
The Journal of International Medical Research; Gao ZZ, Wang F et. al.

Nov 16th, 2021 - An appropriate electrolyte solution is important for safe intraoperative anesthesia management in children. This trial assessed the effectiveness of a novel 1% glucose isotonic electrolyte solution in intraoperative fluid therapy in children. This...

Association of early dysnatremia with mortality in the neonatal intensive care unit: re...
https://doi.org/10.1038/s41372-021-01260-x
Journal of Perinatology : Official Journal of the Califor... Basalely AM, Griffin R et. al.

Nov 15th, 2021 - To determine the association of dysnatremia in the first postnatal week and risk of acute kidney injury (AKI) and mortality. A secondary analysis of 1979 neonates in the AWAKEN cohort evaluated the association of dysnatremia with (1) AKI in the fi...

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Drugs  8 results see all →

Clinicaltrials.gov  15 results

Prospective Analysis Into Development of Hypernatremia in Critically Ill Patients
https://clinicaltrials.gov/ct2/show/NCT05085223

Oct 27th, 2021 - Hypernatremia is frequently encountered in patients admitted to the Intensive Care Unit (ICU) and associated with increased mortality and length of stay. Previous studies focused on predictors in the development and recovery of hypernatremia by in...

Efficacy and Safety of Rapid Intermittent Correction Compared With Slow Continuous Correction in Patients With Severe Hypernatremia
https://clinicaltrials.gov/ct2/show/NCT04949139

Jul 2nd, 2021 - Hypernatremia is defined as serum sodium (sNa) levels above 145 mmol/L and is caused by abnormalities in water balance, mainly in children, elderly, and critically ill patients. It occurs in 3% of hospitalized patients and in 9% of critically ill ...

Effect of Dexmedetomidine on the Minimum Alveolar Concentration of Sevoflurane
https://clinicaltrials.gov/ct2/show/NCT03384563

Jan 27th, 2021 - The anesthetic potency of an inhalational anesthetic is measured by the minimum alveolar concentration (MAC), or the dose required to suppress movement to a surgical stimulus in 50% of patients. This measure of potency may also be used to assess t...

Disturbance of Water and Sodium Metabolism After Surgery of Sellar Lesions, and Correspond Clinical Strategy
https://clinicaltrials.gov/ct2/show/NCT01406041

Mar 19th, 2020 - The fluid and electrolyte imbalance (FEI) is pretty common encountered during the clinical process of patients suffered sellar lesions. Moreover, if the patients are undergone the surgery for remove the lesion, FEI happens in all cases without exc...

Early Induced Hypernatremia for the Prevention and Management of Brain Edema
https://clinicaltrials.gov/ct2/show/NCT02798601

Mar 18th, 2020 - Severe traumatic brain injury is one of the main causes of death in young people. Additionally, it is considered a public health problem because of the high prevalence of motor and cognitive dysfunction in those who survive. One of the cornerstone...

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News  29 results

Bempegaldesleukin/Nivolumab Combo Upholds Durable Benefit in Metastatic Melanoma
https://www.onclive.com/view/bempegaldesleukin-nivolumab-combo-upholds-durable-benefit-in-metastatic-melanoma

Oct 6th, 2021 - November 13, 2020 - The combination of bempegaldesleukin (NKTR-214) and the PD-1 inhibitor nivolumab (Opdivo) elicited a confirmed best overall response rate (ORR) of 53% in efficacy-evaluable patients with metastatic melanoma, according to update...

Inpatient Sodium Imbalances Linked to Adverse COVID-19 Outcomes
https://www.medscape.com/viewarticle/947165

Mar 10th, 2021 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. Both high and low serum sodium levels are associated with adverse outcomes for hospitalized patients with COVID-19, new research suggests. In the ...

Isotonic Fluids Without Potassium Could Be Harmful for Some Acutely Ill Kids
https://www.medscape.com/viewarticle/939875

Oct 28th, 2020 - NEW YORK (Reuters Health) - A recent move to use isotonic rather than hypotonic intravenous fluids (IVFs) in acutely ill children could be boosting their risk of developing electrolyte disorders, a new trial suggests. "Commercially available isoto...

Fast Five Quiz: Heart Failure Presentation and Diagnosis
https://reference.medscape.com/viewarticle/912857_5

Apr 23rd, 2020 - BNP is the strongest predictor of heart failure vs other causes of dyspnea. High LV filling pressures stimulate the release of BNP, which exerts diuretic, natriuretic, and antihypertensive effects by inhibiting the renin-angiotensin-aldosterone sy...

Not All Stool Discussions Are Unproductive
https://www.mdedge.com/clinicianreviews/article/212851/pediatrics/not-all-stool-discussions-are-unproductive
David M. Lang, Esq.

Nov 26th, 2019 - On August 22, 2014, a baby girl was born healthy and at full term. She was discharged on August 24 after a routine hospital stay.

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