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About 6,003 results

ALLMedicine™ Hyperuricemia Center

Research & Reviews  1,846 results

Correlation of obesity, dietary patterns, and blood pressure with uric acid: data from ...
https://doi.org/10.1186/s12902-022-01112-5
BMC Endocrine Disorders; Yao J, Zhang Y et. al.

Aug 6th, 2022 - Prevalence rates of hyperuricemia and gout are increasing. Clinical investigations of hyperuricemia-related risk factors aid in the early detection, prevention, and management of hyperuricemia and gout. Ongoing research is examining the associatio...

Chronic kidney disease of nontraditional causes in central Panama.
https://doi.org/10.1186/s12882-022-02907-3
BMC Nephrology; Courville K, Bustamante N et. al.

Aug 6th, 2022 - Over the last three decades, the mesoamerican region has seen an increase in the frequency of patients diagnosed with Chronic Kidney Disease of nontraditional causes (CKDnt) also known as Meso-American Nephropathy (MeN). A region with an increased...

The safety and urate-lowering efficacy of febuxostat in patients undergoing peritoneal ...
https://doi.org/10.21037/apm-22-628
Annals of Palliative Medicine; Ma J, Huang J et. al.

Aug 5th, 2022 - Studies have shown that hyperuricemia (HUA) is an independent risk factor for all-cause death and residual kidney function loss in peritoneal dialysis (PD) patients. The control of blood uric acid (UA) is an important link to improve the prognosis...

Evaluation of serum uric acid and liver function tests among pregnant women with and wi...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352010
PloS One; Hassen FS, Malik T et. al.

Aug 5th, 2022 - Pre-eclampsia can be described as new-onset hypertension (blood pressure ≥140/90 mmHg) together with proteinuria (24-hr urinary protein ≥ 0.3 g) or any indication of end-organ damage after 20 weeks of gestation. Liver and kidney dysfunction, throm...

Hyperuricemia is Associated with the Presence of Metabolically Obese Normal-Weight and ...
https://doi.org/10.1080/07435800.2022.2108049
Endocrine Research; Guerrero-Romero F, Simental-Mendía LE

Aug 4th, 2022 - It is well-recognized that hyperuricemia is a common abnormality among individuals with metabolic syndrome. The objective of this study was to determine whether hyperuricemia is associated with the metabolically obese normal-weight (MONW) and meta...

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Guidelines  2 results

2021 Asia-Pacific League of Associations for Rheumatology clinical practice guideline f...
https://doi.org/10.1111/1756-185X.14266
International Journal of Rheumatic Diseases; Lorenzo JPP, Sollano MHMZ et. al.

Dec 22nd, 2021 - Gout is the most prevalent inflammatory arthritis in the Asia-Pacific region and worldwide. This clinical practice guideline (CPG) aims to provide recommendations based on systematically obtained evidence and values and preferences tailored to the...

Diagnosis and management of glycogen storage disease type I: a practice guideline of th...
https://doi.org/10.1038/gim.2014.128
Genetics in Medicine : Official Journal of the American C... Kishnani PS, Austin SL et. al.

Oct 31st, 2014 - Glycogen storage disease type I (GSD I) is a rare disease of variable clinical severity that primarily affects the liver and kidney. It is caused by deficient activity of the glucose 6-phosphatase enzyme (GSD Ia) or a deficiency in the microsomal ...

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Drugs  206 results see all →

Clinicaltrials.gov  158 results

Allopurinol in Acute Coronary Syndrome
https://clinicaltrials.gov/ct2/show/NCT03745729

Jul 27th, 2022 - The pathogenesis of coronary heart disease is closely related to inflammation. IL-1 beta is an effective target for anti-inflammatory treatment of coronary heart disease. Allopurinol is a drug used for treating hyperuricemia and gout for many year...

Risk Factors and Multiomics Study of Chronic Kidney Disease Caused by Metabolic Diseases
https://clinicaltrials.gov/ct2/show/NCT05476627

Jul 27th, 2022 - With the development of China's economy, people's living standard have improved, and the dietary structure have changed. Metabolic diseases, such as hypertension, diabetes, hyperuricemia and obesity have gradually become an important health burden...

Patients With Asymptomatic Hyperuricemia Have Stronger Local Inflammatory Response and Worse Outcome After Total Knee Arthroplasty
https://clinicaltrials.gov/ct2/show/NCT05476367

Jul 27th, 2022 - We identify all patients who had undergone primary total knee arthroplsty(TKA) from April 1, 2015, to March 30, 2016. Patients are grouped by uric acid level. The knee society score(KSS score) and the hospital for special surgery knee score (HSS s...

Febuxostat Versus Allopurinol on Hepatic Steatosis in MAFLD Patients
https://clinicaltrials.gov/ct2/show/NCT05474560

Jul 26th, 2022 - The aim of this study is to evaluate the effect of urate lowering therapy on improvement of steatosis in metabolic associated fatty liver disease (MAFLD) patients with hyperuricemia, by comparing two xanthine oxidase inhibitors allopurinol (100 mg...

Flow Mediated Dilation in Association With Hyperuricemia
https://clinicaltrials.gov/ct2/show/NCT05342285

Jul 20th, 2022 - Systemic lupus erythematosus (SLE) is a complex autoimmune disease that is characterized by multiple end-organ damage and predominantly affects premenopausal women. Cardiovascular disease is a major cause of morbidity and mortality in systemic lup...

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News  189 results

Benzbromarone Tops Febuxostat for Gout?
https://www.medscape.com/viewarticle/977100

Jul 13th, 2022 - Results from a randomized controlled trial conducted in China found low-dose benzbromarone to be more effective in lowering serum urate levels than low-dose febuxostat (Uloric), with a similar safety profile, in gout with renal uric acid underexcr...

Allopurinol Found Safe in Patients With Concomitant Gout, CKD
https://www.medscape.com/viewarticle/967202

Jan 25th, 2022 - Allopurinol treatment is not associated with increased mortality in patients with gout and chronic kidney disease even at 5 years after starting treatment, a study has found. Around 1 in 5 patients with gout also have chronic kidney disease, and p...

Another Study Confirms Gout Benefit With SGLT2 Inhibitors
https://www.medpagetoday.com/endocrinology/diabetes/95777

Nov 19th, 2021 - Patients with type 2 diabetes taking sodium-glucose cotransporter-2 (SGLT2) inhibitors saw a lower risk for gout, a Taiwanese cohort study found. Compared with patients taking DPP-4 inhibitors, those on an SGLT2 inhibitor had an 11% reduced risk f...

Rolling Submission Completed for Surufatinib in Advanced Neuroendocrine Tumors
https://www.onclive.com/view/rolling-submission-completed-for-surufatinib-in-advanced-neuroendocrine-tumors

May 3rd, 2021 - The rolling submission of a new drug application (NDA) to the FDA for surufatinib for the treatment of patients with pancreatic and non-pancreatic neuroendocrine tumors (NETs) has been completed, according to an announcement from Hutchinson China ...

Entrectinib Impresses in Certain Lung Cancers
https://www.medpagetoday.com/hematologyoncology/lungcancer/91513

Mar 5th, 2021 - A majority of patients with advanced or metastatic ROS1 fusion-positive non-small cell lung cancer (NSCLC) obtained durable remissions with the ROS1 inhibitor entrectinib (Rozlytrek), according to an updated integrated analysis of three clinical t...

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