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About 1,355 results

ALLMedicine™ Metabolic Alkalosis Center

Research & Reviews  271 results

Acquired autoimmune Bartter syndrome in a patient with primary hypothyroidism.
https://doi.org/10.1007/s00296-021-05042-8
Rheumatology International; Nasir N, Mohanty D et. al.

Nov 21st, 2021 - We describe an unusual clinical presentation of autoimmune Bartter syndrome in a patient with primary hypothyroidism. A 65-year-old female patient was admitted with neuromuscular weakness associated with hypokalemia and metabolic alkalosis. She ha...

Efficacy and complications of regional citrate anticoagulation during continuous renal ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576341
Journal of Critical Care; Khadzhynov D, von dem Berge U et. al.

Nov 13th, 2021 - We compared filter survival and citrate-induced complications during continuous renal replacement therapy (CRRT) with regional citrate anticoagulation (RCA) in COVID-19 and Non-COVID-19 patients. In this retrospective study we included all consecu...

Hypocalcemia as the Initial Presentation of Type 2 Bartter Syndrome - A Family Report.
https://doi.org/10.1210/clinem/dgab821
The Journal of Clinical Endocrinology and Metabolism; London S, A Levine M et. al.

Nov 10th, 2021 - Bartter syndrome (BS) is a group of rare autosomal-recessive tubulopathies characterized by hypokalemic, hypochloremic metabolic alkalosis in which the primary defect is a deficiency of transporters involved in sodium chloride reabsorption. Type 2...

Hypertrophic Pyloric Stenosis.
https://doi.org/10.1542/pir.2020-003277
Pediatrics in Review; Rich BS, Dolgin SE

Oct 3rd, 2021 - Hypertrophic pyloric stenosis is a common condition seen in the first 1 to 3 months after birth. Patients typically present with nonbilious projectile emesis after feeds that may result in hypokalemic, hypochloremic metabolic alkalosis. Although i...

A gastric outlet thickened mucosal fold associated with cytomegalovirus infection in an...
https://doi.org/10.1080/20469047.2021.1967626
Paediatrics and International Child Health; Tangirala S, Amboiram P et. al.

Sep 15th, 2021 - Non-bilious vomiting in preterm neonates discharged from neonatal intensive care units is a common complaint and is often associated with benign conditions such as gastro-oesophageal reflux. A neonate of 27 weeks gestation who presented later with...

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Guidelines  1 results

Diagnosis and management of Bartter syndrome: executive summary of the consensus and re...
https://doi.org/10.1016/j.kint.2020.10.035
Kidney International; Konrad M, Nijenhuis T et. al.

Jan 30th, 2021 - Bartter syndrome is a rare inherited salt-losing renal tubular disorder characterized by secondary hyperaldosteronism with hypokalemic and hypochloremic metabolic alkalosis and low to normal blood pressure. The primary pathogenic mechanism is defe...

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Drugs  247 results see all →

Clinicaltrials.gov  10 results

Metabolic Alkalosis in Heart Failure
https://clinicaltrials.gov/ct2/show/NCT04740242

Feb 5th, 2021 - Metabolic alkalosis (MA) is the most common acid-base disorder and when it's severe it can have effects on cellular function and contribute to an increase in mortality. MA is a common complication of heart failure (HF) especially when patients are...

The Influences of Dialysate Bicarbonate Concentrations on Hemodialysis Patients
https://clinicaltrials.gov/ct2/show/NCT04070690

Aug 28th, 2019 - Background: Patients with decreased kidney function are in the positive acid balance due to insufficient renal acid excretion. To correct the varying degrees of metabolic acidosis in these HD patients, a high concentration of HCO3 in the dialysate...

Acetazolamide (AZ) for Management of Alkalosis in Bartter Syndrome
https://clinicaltrials.gov/ct2/show/NCT03847571

Feb 20th, 2019 - Bartter syndrome is a hereditary salt-loosing tubulopathy caused by several gene mutations encoding the sodium reabsorption in the thick ascending limb of loop of Henle, with poor response to treatment. The effects of inhibition of proximal tubula...

Impact of NaHCO3- on Exercise Hyperpnea
https://clinicaltrials.gov/ct2/show/NCT03057535

Feb 20th, 2017 - The ventilatory response (V̇E) to exercise-induced increases in the rate of CO2 production (V̇CO2) depends on the regulated level of arterial PCO2 (PaCO2) and the dead space to tidal volume ratio (VD/VT). An abnormally high V̇E/V̇CO2 response to e...

Substitution of Acetate by Citrate in the Bicarbonate Based Hemodialysis
https://clinicaltrials.gov/ct2/show/NCT02745340

May 4th, 2016 - Acetate is the primary acidifying solution used in bicarbonate-based hemodialysis worldwide. It has been published in small trials or case series that the addition of acetate is associated with a rise in nitric oxide production of vascular smooth ...

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News  13 results

Correction of Dialysis-Induced Metabolic Alkalosis
https://www.mdedge.com/fedprac/article/238422/nephrology/correction-dialysis-induced-metabolic-alkalosis
Assad Mohammedzein, MD, Tarek Naguib, MD

Apr 9th, 2021 - Metabolic alkalosis, a disorder that causes elevations in serum bicarbonate and arterial pH, is a common metabolic abnormality found in nearly half of hospitalized patients but is rare in patients with end-stage renal disease (ESRD) on hemodialysi.

Gastric outlet obstruction: A red flag, potentially manageable
https://www.mdedge.com/ccjm/article/199619/gastroenterology/gastric-outlet-obstruction-red-flag-potentially-manageable?channel=133
Andree H. Koop, MD, William C. Palmer, MD et. al.

May 1st, 2019 - A 72-year-old woman presents to the emergency department with progressive nausea and vomiting. One week earlier, she developed early satiety and nausea with vomiting after eating solid food.

U.S. jury orders DaVita to pay $383.5 million in wrongful death lawsuits
https://www.reuters.com/article/us-davita-lawsuit/u-s-jury-orders-davita-to-pay-383-5-million-in-wrongful-death-lawsuits-idUSKBN1JO1S4

Jun 28th, 2018 - (Reuters) - A federal jury in Colorado has awarded $383.5 million to the families of three patients who said they suffered cardiac arrests and died soon after receiving dialysis treatments at clinics run by DaVita Inc. FILE PHOTO: The outdoor sign...

A 5-Week-Old Boy With Progressive Nonbilious Vomiting: Osmosis USMLE Study Question
https://www.medscape.com/viewarticle/879904_2

Jun 23rd, 2017 - Answer: C. Hypochloremic hypokalemic metabolic alkalosis Infantile hypertrophic pyloric stenosis classically presents with progressive nonbilious projectile emesis and an enlarged pylorus (described as an "olive") upon abdominal examination. Prolo...

A patient with altered mental status and an acid-base disturbance
https://www.mdedge.com/ccjm/article/126539/critical-care/patient-altered-mental-status-and-acid-base-disturbance?channel=327
Shylaja Mani, MD, Gregory W. Rutecki, MD

Jan 1st, 2017 - A 78-year-old black woman with a history of osteoarthrosis and chronic diffuse joint pain presents with altered mental status and tachypnea, which began 3 hours earlier. She lives alone, and her family suspects she abuses both alcohol and her pain.

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