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About 10,981 results

ALLMedicine™ Nephrotoxicity Center

Research & Reviews  5,413 results

Long-Term Immunosuppression Management: Opportunities and Uncertainties.
https://doi.org/10.2215/CJN.15040920
Clinical Journal of the American Society of Nephrology : ... Wojciechowski D, Wiseman A

Apr 15th, 2021 - The long-term management of maintenance immunosuppression in kidney transplant recipients remains complex. The vast majority of patients are treated with the calcineurin inhibitor tacrolimus as the primary agent in combination with mycophenolate, ...

Trimetazidine Protects from Mercury-Induced Kidney Injury.
https://doi.org/10.1159/000514843
Pharmacology Hazelhoff MH, Bulacio RP et. al.

Apr 13th, 2021 - The presence of mercury in the environment is a worldwide concern. Inorganic mercury is present in industrial materials, is employed in medical devices, is widely used in batteries, is a component of fluorescent light bulbs, and it has been associ...

Thymoquinone supplementation ameliorates cisplatin-induced hepatic pathophysiology.
https://doi.org/10.1177/09603271211003645
Human & Experimental Toxicology; Shahid F, Farooqui Z et. al.

Apr 9th, 2021 - Hepatotoxicity is a major dose-limiting side effect of CP chemotherapy besides nephrotoxicity and gastrointestinal dysfunction. TQ, a principal Nigella sativa seed oil constituent, has been shown to improve hepatic functions in various in vivo mod...

MiR-34a/Sirt1/p53 signaling pathway contributes to cadmium-induced nephrotoxicity: A pr...
https://doi.org/10.1016/j.envpol.2021.117029
Environmental Pollution (Barking, Essex : 1987); Hao R, Song X et. al.

Apr 6th, 2021 - Cadmium (Cd), as an environmental pollutant, can lead to nephrotoxicity. However, its nephrotoxicological mechanisms have not been fully elucidated. In this study, Cd (1.5 mg/kg body weight, gavaged for 4 weeks) was found to induce the renal damag...

Low regulatory T-cells: A distinct immunological subgroup in minimal change nephrotic s...
https://doi.org/10.1016/j.trsl.2021.03.019
Translational Research : the Journal of Laboratory and Cl... Chang-Yien C, Teo S et. al.

Apr 3rd, 2021 - Rituximab is an important second line therapy in difficult nephrotic syndrome (NS), especially given toxicity of long-term glucocorticoid or calcineurin inhibitor (CNI) use. However, clinical response to rituximab is heterogenous. We hypothesized ...

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Guidelines  1 results

Prevention of cisplatin nephrotoxicity: state of the art and recommendations from the E...
https://doi.org/10.1007/s00280-008-0711-0
Cancer Chemotherapy and Pharmacology; Launay-Vacher V, Rey JB et. al.

Mar 4th, 2008 - Antineoplastic drugs used in the treatment of cancers present with variable renal tolerance profiles. Among drugs with a potential for renal toxicity, platinum salts, and especially cisplatin is a well-known agent that may induce acute and chronic...

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Drugs  3 results see all →

Clinicaltrials.gov  5,479 results

Long-Term Immunosuppression Management: Opportunities and Uncertainties.
https://doi.org/10.2215/CJN.15040920
Clinical Journal of the American Society of Nephrology : ... Wojciechowski D, Wiseman A

Apr 15th, 2021 - The long-term management of maintenance immunosuppression in kidney transplant recipients remains complex. The vast majority of patients are treated with the calcineurin inhibitor tacrolimus as the primary agent in combination with mycophenolate, ...

Trimetazidine Protects from Mercury-Induced Kidney Injury.
https://doi.org/10.1159/000514843
Pharmacology Hazelhoff MH, Bulacio RP et. al.

Apr 13th, 2021 - The presence of mercury in the environment is a worldwide concern. Inorganic mercury is present in industrial materials, is employed in medical devices, is widely used in batteries, is a component of fluorescent light bulbs, and it has been associ...

Thymoquinone supplementation ameliorates cisplatin-induced hepatic pathophysiology.
https://doi.org/10.1177/09603271211003645
Human & Experimental Toxicology; Shahid F, Farooqui Z et. al.

Apr 9th, 2021 - Hepatotoxicity is a major dose-limiting side effect of CP chemotherapy besides nephrotoxicity and gastrointestinal dysfunction. TQ, a principal Nigella sativa seed oil constituent, has been shown to improve hepatic functions in various in vivo mod...

MiR-34a/Sirt1/p53 signaling pathway contributes to cadmium-induced nephrotoxicity: A pr...
https://doi.org/10.1016/j.envpol.2021.117029
Environmental Pollution (Barking, Essex : 1987); Hao R, Song X et. al.

Apr 6th, 2021 - Cadmium (Cd), as an environmental pollutant, can lead to nephrotoxicity. However, its nephrotoxicological mechanisms have not been fully elucidated. In this study, Cd (1.5 mg/kg body weight, gavaged for 4 weeks) was found to induce the renal damag...

Low regulatory T-cells: A distinct immunological subgroup in minimal change nephrotic s...
https://doi.org/10.1016/j.trsl.2021.03.019
Translational Research : the Journal of Laboratory and Cl... Chang-Yien C, Teo S et. al.

Apr 3rd, 2021 - Rituximab is an important second line therapy in difficult nephrotic syndrome (NS), especially given toxicity of long-term glucocorticoid or calcineurin inhibitor (CNI) use. However, clinical response to rituximab is heterogenous. We hypothesized ...

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News  85 results

Allopurinol reduces risk of renal decline in gout patients
https://www.mdedge.com/familymedicine/article/176618/nephrology/allopurinol-reduces-risk-renal-decline-gout-patients
Internal Medicine News; Will Pass

Oct 8th, 2018 - In patients with gout, at least 300 mg of allopurinol daily may reduce the risk of renal function decline, according to a new study. London_England/Thinkstock Since no evidence supports allopurinol nephrotoxicity and usage does not appear to worse.

Repurposing With a Purpose
https://www.mdedge.com/fedprac/article/168444/hiv/repurposing-purpose
Jan Dyer

Jun 22nd, 2018 - Cryptococcal meningitis is one of the most common mycoses in patients with HIV/AIDS. In developed countries, mortality rates due to the disease hover around 9%—in poor and underdeveloped regions, the number leaps to 70%.

Reducing Nephrotoxicity in Cancer Patients Undergoing CT
https://www.medscape.com/viewarticle/884278

Aug 14th, 2017 - In frail patients with cancer who are to undergo contrast-enhanced CT, the choice of iodated contrast medium can be key to reducing risk for impaired renal function and the development of contrast-induced nephropathy (CIN). In a head-to-head compa...

Paclitaxel + carboplatin should be standard option for advanced cervical cancer
https://www.mdedge.com/obgyn/article/97636/gynecologic-cancer/paclitaxel-carboplatin-should-be-standard-option-advanced
Mary Ann Moon

Mar 3rd, 2015 - Paclitaxel plus carboplatin was noninferior to paclitaxel plus cisplatin in extending overall survival in incurable metastatic or recurrent cervical cancer in a multicenter open-label randomized phase III clinical trial published online March 3 in.

Pain control with ketorolac appears safe after pediatric heart surgery
https://www.mdedge.com/cardiology/article/96819/geriatrics/pain-control-ketorolac-appears-safe-after-pediatric-heart
M. Alexander Otto

Feb 1st, 2015 - PHOENIX – The NSAID ketorolac is safe to use in very young children after cardiac surgery, and dramatically decreases the length of intubation and ICU stay as well as the use of opioids, according to a retrospective cohort study from the Cohen Chi.

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