ALLMedicine™ Nephrotoxicity Center

Dec 2nd, 2021 - In recent years, nuclear medicine imaging and therapy for prostate cancer have radically changed through the introduction of radiolabeled prostate-specific membrane antigen (PSMA)-binding peptides. However, these small molecular probes have some i...

Dec 2nd, 2021 - Nephrotoxicity is an indication for the damage of kidney-specific detoxification and excretion mechanisms by exogenous or endogenous toxicants. Exposure to vancomycin predominantly results in renal damage and losing the control of body homeostasis...

Nov 30th, 2021 - Nephrotoxicity: A growing problem or an exaggerated fear with unpredictable dimensions?|2021|Koç NS,Arici M,|

Nov 26th, 2021 - Nephrotoxicity is one of the concerns of prolonged maintenance therapy with pemetrexed. No reversible risk factors for pemetrexed-induced nephrotoxicity have been identified in previous studies. Identification of such factors would be clinically m...

Nov 23rd, 2021 - Among v-raf murine sarcoma viral oncogene homolog B1 inhibitors, vemurafenib causes a higher incidence of nephrotoxicity. Bai et al. reported that vemurafenib-induced nephrotoxicity is not directly caused by viral oncogene homolog B1 inhibition bu...

Apr 1st, 2020 - Recent vancomycin PK/PD and toxicodynamic studies enable a reassessment of the current dosing and monitoring guideline in an attempt to further optimize the efficacy and safety of vancomycin therapy. The area-under-the-curve to minimum inhibitory ...

Nov 16th, 2021 - Several studies suggest that the micronutrient status determines the progression of the HIV infection to AIDS. This phenomenon may be explained by a vicious cycle of malnutrition and infection. Here, the immune system needs energy and micronutrien...

Nov 10th, 2021 - Pulmonary mucormycosis is a relatively a rare disease with a high mortality. The angioinvasion associated with mucormycosis prevents efficient drug delivery at the diseased site. Inhaled amphotericin B achieves drug levels in lung tissue and has b...

Oct 25th, 2021 - Assess the risk of vancomycin-associated nephrotoxicity and outcomes associated with continuous infusions (CI) versus II dosing in the outpatient parenteral antibiotic therapy (OPAT) setting

Oct 14th, 2021 - Why is MRI important in the management of brain AVMs i.e. over conventional catheter angiography? The "gold standard" for evaluation of brain AVMs is catheter angiography. However, the procedure is invasive, involves ionizing radiation, exposure t...

Sep 8th, 2021 - Immunosuppressive therapy with the calcineurin inhibitors (CNI) cyclosporine (CsA) and Tacrolimus (Tac), have radically changed the field of organ transplantation. Ironically, although extensively and effectively used for kidney transplantation an...

Nov 24th, 2021 - The FDA approved the first drug for refractory post-transplant cytomegalovirus (CMV), in patients ages 12 and older, the agency announced late on Tuesday. Maribavir (Livtencity), an oral antiviral, was approved for children and adults who weigh at...

Oct 29th, 2021 - Mrs. C, age 68, is experiencing worsening paranoid delusions.

Aug 11th, 2021 - Topical vancomycin powder failed to reduce periprosthetic joint infection after hip and knee arthroplasty, based on data from approximately 5000 patients. Periprosthetic joint infection (PJI) remains a common complication of hip and knee arthropla...

Jun 1st, 2021 - Lithium is one of the most widely used mood stabilizers and is considered a first-line treatment for bipolar disorder because of its proven antimanic and prophylactic effects. 1 This medication also can reduce the risk of suicide in patients with b.

May 4th, 2021 - Lobaplatin-based induction plus chemoradiation was as effective as, and safer than, a cisplatin-based regimen in a phase 3 trial of more than 500 patients with advanced nasopharyngeal carcinoma. The lobaplatin regimen proved to be a "promising alt...