ALLMedicine™ Focal Segmental Glomerulosclerosis Center

Mar 29th, 2021 - Podocalyxin (PODXL) is a highly sialylated adhesion glycoprotein that plays an important role in podocyte's physiology. Recently, missense and nonsense dominant variants in the PODXL gene have been associated with focal segmental glomerulosclerosi...

Mar 10th, 2021 - A Case of Focal Segmental Glomerulosclerosis.|2021|Hogan JJ,|

Mar 1st, 2021 - Angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) are prescribed as conservative or adjunctive therapies for adult idiopathic nephrotic syndrome. However, studies on real-world practice patterns are scarce. ...

Mar 1st, 2021 - The G1 and G2 alleles of apolipoprotein L1 (APOL1) are common in the Black population and associated with increased risk of focal segmental glomerulosclerosis (FSGS). The molecular mechanisms linking APOL1 risk variants with FSGS are not clearly u...

Feb 17th, 2021 - From rat studies, human case reports and cohort studies, bisphosphonates seem to impair renal function. However, when critically reviewing the literature, zoledronate and pamidronate are more frequently involved in renal deterioration than other b...

Feb 5th, 2018 - HIV-positive individuals are at increased risk for kidney disease, including HIV-associated nephropathy, noncollapsing focal segmental glomerulosclerosis, immune-complex kidney disease, and comorbid kidney disease, as well as kidney injury resulti...

Mar 29th, 2021 - Podocalyxin (PODXL) is a highly sialylated adhesion glycoprotein that plays an important role in podocyte's physiology. Recently, missense and nonsense dominant variants in the PODXL gene have been associated with focal segmental glomerulosclerosi...

Mar 10th, 2021 - A Case of Focal Segmental Glomerulosclerosis.|2021|Hogan JJ,|

Mar 1st, 2021 - Angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) are prescribed as conservative or adjunctive therapies for adult idiopathic nephrotic syndrome. However, studies on real-world practice patterns are scarce. ...

Mar 1st, 2021 - The G1 and G2 alleles of apolipoprotein L1 (APOL1) are common in the Black population and associated with increased risk of focal segmental glomerulosclerosis (FSGS). The molecular mechanisms linking APOL1 risk variants with FSGS are not clearly u...

Feb 17th, 2021 - From rat studies, human case reports and cohort studies, bisphosphonates seem to impair renal function. However, when critically reviewing the literature, zoledronate and pamidronate are more frequently involved in renal deterioration than other b...

Dec 28th, 2016 - Bone Marrow-Derived Immature Myeloid Cells Are a Main Source of Circulating suPAR Contributing to Proteinuric Kidney Disease Hahm E, Wei C, Fernandez I, et al Nat Med. 2016 Dec 12. [Epub ahead of print] Remember when we first learned that many gas...

Nov 27th, 2016 -   CHICAGO — Sparsentan, which was developed for the treatment of hypertension, is emerging as a targeted therapy for primary focal segmental glomerulosclerosis (FSGS), research from the phase 2 DUET trial suggests. "Primary focal segmental glomeru...

Nov 27th, 2016 -   CHICAGO — Sparsentan, which was developed for the treatment of hypertension, is emerging as a targeted therapy for primary focal segmental glomerulosclerosis (FSGS), research from the phase 2 DUET trial suggests. "Primary focal segmental glomeru...

Nov 10th, 2012 - Action Points This study analyzed circulating soluble urokinase receptor levels in two cohorts of children and adults with biopsy proven primary focal segmental glomerulosclerosis. The investigators found significantly elevated levels in both grou...

Jan 5th, 2012 - Mycophenolate versus Azathioprine as Maintenance Therapy for Lupus Nephritis Dooley MA, Jayne D, Ginzler EM, ALMS Group, et al N Engl J Med. 2011;365:1886-1895 The treatment of lupus nephritis has long been controversial due to a number of factors...