×
About 22,718 results

ALLMedicine™ Proteinuria Center

Research & Reviews  7,145 results

Analyses of Proteinuria, Renal Infiltration of Leukocytes, and Renal Deposition of Prot...
https://doi.org/10.3791/63506
Journal of Visualized Experiments : JoVE; Cabana-Puig X, Luo XM

Jun 28th, 2022 - Systemic lupus erythematosus (SLE) is an autoimmune disorder with no known cure and is characterized by persistent inflammation in many organs, including the kidneys. Under such circumstances, the kidney loses its ability to clean waste from the b...

Results from a national-wide retrospective cohort measure the impact of C3 and soluble ...
https://doi.org/10.1016/j.kint.2022.05.027
Kidney International; Chauvet S, Hauer JJ et. al.

Jun 26th, 2022 - C3 glomerulopathy (C3G) is a rare complement-mediated disease. Specific treatments are not yet available and factors predictive of kidney survival such as age, kidney function and proteinuria are not specific to C3G. The prognostic value of biomar...

Increased glucocorticoid metabolism in diabetic kidney disease.
https://doi.org/10.1371/journal.pone.0269920
PloS One; Ackermann D, Vogt B et. al.

Jun 25th, 2022 - Glomerular damage indicated by proteinuria is a main symptom in diabetic nephropathy. Mineralocorticoid receptor (MR) antagonists (MRAs) are beneficial irrespective of aldosterone availability. Thus, we hypothesized an alternatively activated MR t...

A Phase 1 Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ManNAc in Subjects With Primary Podocyte Diseases
https://clinicaltrials.gov/ct2/show/NCT02639260

Jun 24th, 2022 - Background. ManNAc (N-acetyl D-mannosamine) is an uncharged monosaccharide that is the biologic precursor of N-acetyl neuraminic acid (Neu5Ac, sialic acid). Sialic acids are the negatively charged, terminal monosaccharides of carbohydrate chains t...

see more →

Guidelines  8 results

Management of congenital nephrotic syndrome: consensus recommendations of the ERKNet-ES...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8128706
Nature Reviews. Nephrology; Boyer O, Schaefer F et. al.

Jan 31st, 2021 - Congenital nephrotic syndrome (CNS) is a heterogeneous group of disorders characterized by nephrotic-range proteinuria, hypoalbuminaemia and oedema, which manifest in utero or during the first 3 months of life. The main cause of CNS is genetic def...

IPNA clinical practice recommendations for the diagnosis and management of children wit...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316686
Pediatric Nephrology (Berlin, Germany); Trautmann A, Vivarelli M et. al.

May 10th, 2020 - Idiopathic nephrotic syndrome newly affects 1-3 per 100,000 children per year. Approximately 85% of cases show complete remission of proteinuria following glucocorticoid treatment. Patients who do not achieve complete remission within 4-6 weeks of...

2019 Update of the Joint European League Against Rheumatism and European Renal Associat...
https://doi.org/10.1136/annrheumdis-2020-216924
Annals of the Rheumatic Diseases; Fanouriakis A, Kostopoulou M et. al.

Mar 30th, 2020 - To update the 2012 EULAR/ERA-EDTA recommendations for the management of lupus nephritis (LN). Following the EULAR standardised operating procedures, a systematic literature review was performed. Members of a multidisciplinary Task Force voted inde...

Management of hepatitis C virus infection in patients with chronic kidney disease: posi...
https://doi.org/10.1007/s40620-018-0523-1 10.1111/ctr.12941 10.1111/tid.12696
Journal of Nephrology; Minutolo R, Aghemo A et. al.

Sep 27th, 2018 - Hepatitis C virus (HCV) infection is now considered a systemic disease due to the occurrence of extra-hepatic manifestations. Among these, the renal involvement is frequent. HCV infection, in fact, is strongly associated with proteinuria and chron...

A best-practice position statement on pregnancy after kidney transplantation: focusing ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182355
Journal of Nephrology; Cabiddu G, Spotti D et. al.

Jun 28th, 2018 - Kidney transplantation (KT) is often considered to be the method best able to restore fertility in a woman with chronic kidney disease (CKD). However, pregnancies in KT are not devoid of risks (in particular prematurity, small for gestational age ...

see more →

Drugs  609 results see all →

Clinicaltrials.gov  731 results

A Phase 1 Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ManNAc in Subjects With Primary Podocyte Diseases
https://clinicaltrials.gov/ct2/show/NCT02639260

Jun 24th, 2022 - Background. ManNAc (N-acetyl D-mannosamine) is an uncharged monosaccharide that is the biologic precursor of N-acetyl neuraminic acid (Neu5Ac, sialic acid). Sialic acids are the negatively charged, terminal monosaccharides of carbohydrate chains t...

A Study to Learn More About How Well the Study Treatment Finerenone Works, How Safe it is, How it Moves Into, Through, and Out of the Body, and the Effects it Has on the Body When Taken With an ACE...
https://clinicaltrials.gov/ct2/show/NCT05196035

Jun 24th, 2022 - Researchers are looking for a better way to treat children who have chronic kidney disease (CKD), which is long-term kidney disease, and proteinuria, a condition in which a person´s kidneys leak protein into the urine. The kidneys filter waste and...

Impact of Donor-Specific Antibodies in (Highly-) Immunized Living Donor Kidney Transplant Recipients
https://clinicaltrials.gov/ct2/show/NCT05431712

Jun 24th, 2022 - Kidney transplantation is the preferred treatment for end-stage renal disease. Alongside limited availability of donors, rejection and premature graft loss are main barriers to kidney transplantation. Donor-specific antibodies pre-transplantation ...

Rituximab Plus Cyclosporine in Idiopathic Membranous Nephropathy
https://clinicaltrials.gov/ct2/show/NCT00977977

Jun 24th, 2022 - This is a pilot intervention study to evaluate preliminary evidence of the safety and effectiveness of a novel combination immunosuppressive regimen, Rituximab plus cyclosporine, in the treatment of idiopathic membranous nephropathy. Membranous ne...

TAB008 Compared to Avastin® in Patients With EGFR Wild-type Non-squamous Non-small Cell Lung Cancer
https://clinicaltrials.gov/ct2/show/NCT05427305

Jun 22nd, 2022 - This randomized, double-blind, equivalence study was conducted in China. Treatment naïve, EGFR wild-type (by PCR or NGS) nsNSCLC patients were enrolled. Patients had to be between 18-75 years of age; stage IIIB to IV pathology confirmed nsNSCLC; E...

see more →

News  587 results

Which CRC Regimens Are More Likely to Harm Kidneys?
https://www.medscape.com/viewarticle/974095

May 17th, 2022 - The study was published on researchsquare.com as a preprint and has not yet been peer reviewed. Key Takeaways Among the various chemotherapy options for metastatic colorectal cancer (CRC), FOLFIRI + bevacizumab is the most likely to cause acute ki...

43-year-old male • fatigue • unintentional weight loss • pancytopenia • Dx?
https://www.mdedge.com/familymedicine/article/254462/musculoskeletal-disorders
MDedge Family Medicine; Isabella Buzzo Bellon Brout, MD, Caitlin A. Nicholson, MD et. al.

May 10th, 2022 - THE CASE A 43-year-old Black male presented to his primary care physician with an 8-month history of progressive fatigue, weakness, and unintentional weight loss. The patient’s history also included antiphospholipid antibody syndrome (APS) with pr.

FDA Issues Complete Response Letter to Toripalimab for Nasopharyngeal Carcinoma
https://www.onclive.com/view/fda-issues-complete-response-letter-to-toripalimab-for-nasopharyngeal-carcinoma

May 2nd, 2022 - The FDA has issued a complete response letter (CRL) to the biologics license application (BLA) seeking the approval of toripalimab for use in combination with gemcitabine and cisplatin in the frontline treatment of patients with advanced recurrent...

FDA Issues Complete Response Letter to Surufatinib for Advanced Neuroendocrine Tumors
https://www.onclive.com/view/fda-issues-complete-response-letter-to-surufatinib-for-advanced-neuroendocrine-tumors

May 2nd, 2022 - The FDA has issued a complete response letter (CRL) to the new drug application (NDA) seeking the approval of surufatinib for the treatment of patients with pancreatic and extra-pancreatic neuroendocrine tumors (NETs), according to an announcement...

Normalized Hypothyroidism Linked With Improved Kidney Function
https://www.medscape.com/viewarticle/972275

Apr 18th, 2022 - The study covered in this summary was published on Research Square as a preprint and has not yet been peer reviewed. Key Takeaway In a single-center, retrospective study of 52 patients with overt hypothyroidism — defined as having low levels of fr...

see more →

Patient Education  7 results see all →